| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Saw 3D | $49,598 | - | 8 | - | $6,199 | $66,166 | 1 | ACME | true | false |
| 2 | 1 | Despicable Me | $44,738 | -39.1% | 16 | - | $2,796 | $356,424 | 3 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | Eat Pray Love | $15,170 | -42.7% | 6 | -1 | $2,528 | $201,783 | 4 | ACME | false | false |
| 4 | - | The Switch | $11,665 | - | 4 | - | $2,916 | $17,223 | 1 | ACME | true | false |
| 5 | 3 | The Social Network | $10,850 | -45.6% | 6 | -1 | $1,808 | $67,381 | 2 | ACME | false | false |
| 6 | 4 | RED | $9,524 | -27.8% | 4 | - | $2,381 | $59,262 | 3 | ACME | false | false |
| 7 | 5 | The Town | $5,854 | -39.4% | 4 | - | $1,463 | $46,807 | 3 | - | false | false |
| 8 | 6 | Devil | $4,778 | -37% | 2 | - | $2,389 | $21,750 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 8 | Buried | $3,791 | -19.2% | 3 | -2 | $1,263 | $88,490 | 5 | Incognito Films | false | false |
| 10 | 7 | Legend of the Guardians: The Owls of Ga'Hoole | $3,170 | -46.8% | 5 | -2 | $634 | $132,136 | 5 | - | false | false |
| 11 | 11 | Inception | $2,214 | -4% | 3 | -1 | $738 | $361,507 | 15 | - | false | false |
| 12 | 9 | A Turtle's Tale: Sammy's Adventures | $1,838 | -43.2% | 2 | -2 | $919 | $97,601 | 7 | ACME | false | false |
| 13 | 13 | The Other Guys | $1,618 | -12.3% | 1 | -2 | $1,618 | $67,774 | 5 | ACME | false | false |
| 14 | 12 | Stone | $792 | -57.3% | 3 | -1 | $264 | $23,149 | 4 | Incognito Films | false | false |
| 15 | 15 | The Girl with the Dragon Tattoo | $617 | -42.4% | 2 | - | $308 | $28,011 | 11 | Incognito Films | false | false |
| 16 | 20 | Soul Kitchen | $579 | -0.9% | 1 | - | $579 | $10,554 | 10 | - | false | false |
| 17 | 14 | Hong Kong Confidential | $487 | -62.6% | 1 | -1 | $487 | $123,505 | 7 | MEED Films | false | false |
| 18 | 21 | Going the Distance | $453 | +14.7% | 1 | - | $453 | $69,211 | 8 | - | false | false |
| 19 | 16 | Avatar | $358 | -56.4% | 2 | -1 | $179 | $1,490,564 | 46 | 20th Century Fox International | false | false |
| 20 | 27 | Marmaduke | $354 | +723.3% | 3 | +1 | $118 | $29,611 | 10 | Universal Pictures International (UPI) | false | false |
| 21 | - | The Last Airbender | $253 | - | 1 | - | $253 | $157,856 | 11 | Universal Pictures International (UPI) | false | false |
| 22 | 22 | All That I Love | $209 | -5.4% | 1 | - | $209 | $157,856 | 6 | - | false | false |
| 23 | 19 | Of Love and Other Demons | $56 | -91.4% | 2 | - | $28 | $18,396 | 6 | Incognito Films | false | false |
| 24 | 26 | Prince of Persia: The Sands of Time | $6 | -90.8% | 1 | - | $6 | $183,030 | 23 | Universal Pictures International (UPI) | false | false |
