| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Despicable Me | $992,106 | +72.3% | 123 | - | $8,065 | $2,566,582 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 3 | Zot van A. | $575,006 | +9.5% | 36 | - | $15,972 | $2,457,301 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 3 | - | Due Date | $465,279 | - | 48 | - | $9,693 | $465,279 | 1 | Warner Bros. | true | false |
| 4 | 2 | The Social Network | $324,357 | -39% | 41 | - | $7,911 | $1,145,358 | 2 | Sony Pictures Releasing | false | false |
| 5 | 8 | Arthur 3: The War of the Two Worlds | $287,806 | +94.3% | 56 | - | $5,139 | $952,107 | 3 | Belga Films | false | false |
| 6 | 7 | Legend of the Guardians: The Owls of Ga'Hoole | $275,669 | +80.1% | 75 | -5 | $3,675 | $1,246,606 | 4 | Warner Bros. | false | false |
| 7 | 4 | Paranormal Activity 2 | $269,980 | -36.9% | 20 | - | $13,499 | $1,126,274 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Little White Lies | $244,668 | +6.8% | 24 | - | $10,194 | $894,047 | 3 | Cinéart | false | false |
| 9 | - | Jackass 3D | $196,655 | - | 19 | - | $10,350 | $225,931 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 5 | The American | $196,617 | -23.9% | 35 | - | $5,617 | $597,738 | 2 | Benelux Film Distributors | false | false |
| 11 | - | Sinterklaas en het pakjesmysterie | $158,252 | - | 19 | - | $8,329 | $162,815 | 1 | N/A | true | false |
| 12 | - | Buried | $150,015 | - | 28 | - | $5,357 | $251,855 | 1 | Belga Films | true | false |
| 13 | 9 | Eat Pray Love | $84,287 | -33.3% | 40 | - | $2,107 | $1,275,762 | 5 | Sony Pictures Releasing | false | false |
| 14 | 18 | A Turtle's Tale: Sammy's Adventures | $82,370 | +159.4% | 36 | +1 | $2,288 | $2,211,634 | 14 | Kinepolis Film Distribution (KFD) | false | false |
| 15 | 10 | The Town | $73,177 | -34.1% | 21 | -4 | $3,484 | $1,169,300 | 6 | Warner Bros. | false | false |
| 16 | 11 | Vampires Suck | $61,335 | -32.9% | 30 | -10 | $2,044 | $972,504 | 5 | 20th Century Fox International | false | false |
| 17 | 12 | Sarah's Key | $58,416 | -13.1% | 20 | -2 | $2,920 | $399,150 | 4 | Benelux Film Distributors | false | false |
| 18 | 22 | You Will Meet a Tall Dark Stranger | $53,042 | +144.9% | 21 | - | $2,525 | $298,376 | 3 | Paradiso Entertainment | false | false |
| 19 | - | The Princess of Montpensier | $43,530 | - | 14 | - | $3,109 | $44,879 | 1 | Universal Pictures International (UPI) | true | false |
| 20 | 17 | Inception | $25,667 | -22.9% | 12 | -5 | $2,138 | $6,124,857 | 16 | Warner Bros. | false | false |
| 21 | 14 | Wall Street: Money Never Sleeps | $24,093 | -47.5% | 15 | -15 | $1,606 | $1,242,394 | 7 | 20th Century Fox International | false | false |
| 22 | 21 | Marmaduke | $23,126 | +1.4% | 7 | -17 | $3,303 | $1,294,323 | 12 | 20th Century Fox International | false | false |
| 23 | 16 | Oxygen | $22,045 | -34.5% | 19 | -2 | $1,160 | $856,794 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 24 | 19 | Turquaze | $20,407 | -34.2% | 8 | -4 | $2,550 | $329,934 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 25 | - | Black Venus | $16,320 | - | 8 | - | $2,040 | $19,036 | 1 | N/A | true | false |
| 26 | 15 | Resident Evil: Afterlife | $15,689 | -65.5% | 13 | -17 | $1,206 | $956,383 | 6 | Belga Films | false | false |
| 27 | 20 | Grown Ups | $14,531 | -42.7% | 16 | -9 | $908 | $939,889 | 9 | Sony Pictures Releasing | false | false |
| 28 | - | Kill Me Please | $13,657 | - | 7 | - | $1,951 | $37,028 | 1 | N/A | true | false |
| 29 | 23 | I Am Love | $13,458 | -30.7% | 8 | - | $1,682 | $276,362 | 6 | Cinéart | false | false |
| 30 | - | Briefgeheim | $11,135 | - | 4 | - | $2,783 | $11,135 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 31 | 27 | Poetry | $6,831 | -13.4% | 5 | - | $1,366 | $22,065 | 2 | Benelux Film Distributors | false | false |
| 32 | 25 | Tamara Drewe | $6,569 | -17.8% | 9 | - | $729 | $310,108 | 8 | Cinéart | false | false |
| 33 | 29 | The Expendables | $6,480 | -3.7% | 2 | -9 | $3,240 | $2,686,544 | 12 | Benelux Film Distributors | false | false |
| 34 | 24 | Illégal | $5,781 | -51.9% | 10 | -4 | $578 | $111,288 | 5 | N/A | false | false |
| 35 | 38 | Step Up 3D | $5,152 | +65.4% | 3 | -3 | $1,717 | $3,569,515 | 14 | Belga Films | false | false |
| 36 | 36 | Piranha 3D | $5,096 | +27.2% | 3 | -4 | $1,698 | $1,101,948 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 37 | 35 | Salt | $3,548 | -21.5% | 1 | - | $3,548 | $1,774,641 | 14 | Sony Pictures Releasing | false | false |
| 38 | 26 | The Last Exorcism | $3,415 | -57.2% | 5 | -1 | $683 | $279,455 | 8 | Cinéart | false | false |
| 39 | - | The Big Picture | $2,419 | - | 12 | - | $201 | $4,242 | 1 | N/A | true | false |
| 40 | 30 | Twelve | $2,187 | -61.7% | 4 | -3 | $546 | $186,347 | 7 | Benelux Film Distributors | false | false |
| 41 | 46 | Furry Vengeance | $1,521 | +496.5% | 3 | - | $507 | $210,344 | 16 | Belga Films | false | false |
| 42 | 37 | Exam | $1,496 | -57.6% | 1 | - | $1,496 | $26,113 | 4 | Benelux Film Distributors | false | false |
| 43 | 28 | The Sorcerer's Apprentice | $1,282 | -81.9% | 1 | -4 | $1,282 | $2,089,916 | 13 | Walt Disney Pictures | false | false |
| 44 | 44 | Five Minutes of Heaven | $308 | -43.8% | 2 | -20 | $154 | $2,480 | 3 | Benelux Film Distributors | false | false |
| 45 | 49 | The Disappearance of Alice Creed | $268 | +75.2% | 2 | +1 | $134 | $69,862 | 8 | Benelux Film Distributors | false | false |
| 46 | 48 | Women Without Men | $239 | +13.3% | 2 | - | $119 | $27,954 | 10 | Benelux Film Distributors | false | false |
| 47 | 50 | Four Lovers | $201 | +32.2% | 1 | -3 | $201 | $33,232 | 7 | Benelux Film Distributors | false | false |
| 48 | 47 | The Ghost Writer | $24 | -88.8% | 1 | -4 | $24 | $933,211 | 33 | Benelux Film Distributors | false | false |
