Spanish 2010 Weekend 42
October 15-17, 2010
Key:New This Week
| Rank | LW | Release | Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | Despicable Me | $2,241,592 | -34.8% | 542 | +166 | $4,135 | $8,218,564 | 2 | United International Pictures |
| 2 | - | The Social Network | $1,809,205 | - | 339 | - | $5,336 | $1,809,205 | 1 | Sony Pictures Releasing |
| 3 | 2 | Wall Street: Money Never Sleeps | $1,111,488 | -50.4% | 347 | +9 | $3,203 | $4,721,196 | 2 | 20th Century Fox International |
| 4 | 3 | Saw VI | $594,560 | -52.7% | 212 | +1 | $2,804 | $2,592,243 | 2 | DeAPlaneta |
| 5 | 4 | Vampires Suck | $535,673 | -56.9% | 319 | -9 | $1,679 | $4,157,054 | 3 | 20th Century Fox International |
| 6 | - | Di Di Hollywood | $523,886 | - | 234 | - | $2,238 | $523,886 | 1 | Warner Bros. |
| 7 | 5 | Eat Pray Love | $420,577 | -50.6% | 296 | -20 | $1,420 | $6,008,241 | 4 | Sony Pictures Releasing |
| 8 | 6 | Buried | $351,847 | -45.4% | 200 | - | $1,759 | $2,568,341 | 3 | Warner Bros. |
| 9 | 7 | Letters to Juliet | $296,022 | -49.1% | 258 | - | $1,147 | $1,255,835 | 2 | TriPictures |
| 10 | - | Black Bread | $216,578 | - | 75 | - | $2,887 | $216,578 | 1 | N/A |
| 11 | 9 | Charlie St. Cloud | $154,996 | -63.6% | 194 | -64 | $798 | $1,612,617 | 3 | United International Pictures |
| 12 | - | The New Daughter | $150,781 | - | 52 | - | $2,899 | $150,781 | 1 | N/A |
| 13 | 8 | Machete | $148,135 | -66.1% | 204 | -50 | $726 | $1,911,519 | 3 | Sony Pictures Releasing |
| 14 | 10 | The Sorcerer's Apprentice | $142,047 | -58.8% | 175 | -56 | $811 | $8,571,107 | 7 | Walt Disney Pictures |
| 15 | 11 | Amador | $141,669 | -53.9% | 139 | -1 | $1,019 | $663,485 | 2 | Alta Films |
| 16 | 13 | Avatar 2010 Special Edition | $127,815 | -54.2% | 118 | -14 | $1,083 | $1,847,247 | 4 | 20th Century Fox International |
| 17 | 14 | Inception | $123,370 | -47.2% | 86 | -39 | $1,434 | $22,361,002 | 11 | Warner Bros. |
| 18 | 12 | The American | $105,953 | -65.2% | 124 | -107 | $854 | $4,538,704 | 5 | United International Pictures |
| 19 | 15 | The Outlaw | $74,754 | -48.4% | 92 | -50 | $812 | $4,883,182 | 7 | 20th Century Fox International |
| 20 | 17 | Tinker Bell and the Great Fairy Rescue | $60,680 | -47% | 83 | -5 | $731 | $1,839,719 | 7 | Walt Disney Pictures |
| 21 | 19 | Carancho | $54,149 | -50.5% | 41 | -11 | $1,320 | $704,397 | 4 | Golem Distribución |
| 22 | 16 | Resident Evil: Afterlife | $51,385 | -57.8% | 110 | -33 | $467 | $7,769,633 | 6 | Sony Pictures Releasing |
| 23 | 18 | You Will Meet a Tall Dark Stranger | $48,764 | -57.3% | 48 | -22 | $1,015 | $6,022,328 | 8 | Alta Films |
| 24 | 21 | Step Up 3D | $38,615 | -61.1% | 72 | -35 | $536 | $2,544,440 | 5 | Walt Disney Pictures |
| 25 | - | The Stoning of Soraya M. | $37,974 | - | 42 | - | $904 | $37,974 | 1 | N/A |
| 26 | 22 | Toy Story 3 | $35,857 | -58.7% | 95 | -85 | $377 | $33,885,866 | 13 | Walt Disney Pictures |
| 27 | 20 | The Karate Kid | $32,874 | -67.3% | 102 | -63 | $322 | $11,700,397 | 8 | Sony Pictures Releasing |
| 28 | 24 | Astro Boy | $28,818 | -55.1% | 83 | -36 | $347 | $635,393 | 4 | DeAPlaneta |
| 29 | - | Louise hires a contract killer | $27,942 | - | 16 | - | $1,746 | $27,942 | 1 | Karma Films |
| 30 | 25 | Bicicleta, cullera, poma | $23,252 | -60.1% | 20 | -4 | $1,162 | $239,638 | 3 | Sagrera TV |
| 31 | 23 | The Great Vazquez | $22,369 | -72.2% | 42 | -57 | $532 | $1,153,243 | 4 | Alta Films |
| 32 | 27 | My Afternoons with Margueritte | $17,058 | -29.6% | 17 | -3 | $1,003 | $968,818 | 9 | Golem Distribución |
| 33 | - | How Much Does Your Building Weigh, Mr Foster? | $14,086 | - | 5 | - | $2,817 | $59,985 | 2 | N/A |
| 34 | 28 | Abel | $10,316 | -53.7% | 16 | -8 | $644 | $106,098 | 3 | Alta Films |
| 35 | 26 | Salt | $7,000 | -74.5% | 29 | -21 | $241 | $8,018,310 | 9 | Sony Pictures Releasing |
| 36 | 35 | The Extraordinary Adventures of Adèle Blanc-Sec | $6,540 | -40.5% | 16 | -13 | $408 | $1,221,401 | 6 | TriPictures |
| 37 | 32 | Todo lo que tú quieras | $5,756 | -56.1% | 9 | -6 | $639 | $534,182 | 6 | Wanda Visión S.A. |
| 38 | 30 | Blood Money | $5,708 | -61.5% | 40 | +5 | $142 | $32,294 | 2 | N/A |
| 39 | 34 | Ramona and Beezus | $5,352 | -53.3% | 10 | -3 | $535 | $144,607 | 5 | 20th Century Fox International |
| 40 | 31 | Undertow | $5,081 | -65.6% | 13 | -8 | $390 | $192,329 | 5 | Karma Films |
| 41 | 33 | Heaven on Earth 2010 Re-release | $5,002 | -59.4% | 14 | - | $357 | $59,756 | 3 | Karma Films |
| 42 | 37 | Bright Star | $2,984 | -30.2% | 5 | +1 | $596 | $413,959 | 7 | Vértigo Films |
| 43 | 36 | Grown Ups | $2,949 | -62.6% | 17 | +2 | $173 | $8,498,213 | 12 | Sony Pictures Releasing |
| 44 | 41 | Going the Distance | $2,489 | +77.7% | 2 | -9 | $1,244 | $1,139,447 | 6 | Warner Bros. |
| 45 | 29 | You Again | $1,462 | -90.7% | 8 | -2 | $182 | $27,190 | 2 | Walt Disney Pictures |
| 46 | 40 | Cats & Dogs: The Revenge of Kitty Galore | $603 | -70.4% | 5 | -6 | $120 | $2,688,106 | 9 | Warner Bros. |
| 47 | - | The Expendables | $506 | - | 2 | - | $253 | $6,065,276 | 10 | United International Pictures |
| 48 | 43 | Free Rainer 2010 Re-release | $331 | -64.3% | 5 | +2 | $66 | $70,329 | 8 | N/A |
| 49 | 45 | The Secret of Kells | $161 | -68.6% | 1 | - | $161 | $62,407 | 9 | Karma Films |
