| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Despicable Me | $2,954,228 | -27.4% | 697 | - | $4,238 | $21,234,530 | 4 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Conference of Animals | $2,205,439 | -19% | 643 | - | $3,429 | $9,349,653 | 3 | Constantin Film | false | false |
| 3 | - | Wall Street: Money Never Sleeps | $2,099,349 | - | 353 | - | $5,947 | $2,280,495 | 1 | 20th Century Fox International | true | false |
| 4 | - | Life as We Know It | $1,679,256 | - | 403 | - | $4,166 | $2,016,450 | 1 | Warner Bros. | true | false |
| 5 | 3 | The Social Network | $1,196,096 | -39.9% | 389 | +22 | $3,074 | $7,387,619 | 3 | Sony Pictures Releasing | false | false |
| 6 | 4 | The Other Guys | $1,155,005 | -37.4% | 365 | +13 | $3,164 | $3,760,526 | 2 | Sony Pictures Releasing | false | false |
| 7 | 6 | Legend of the Guardians: The Owls of Ga'Hoole | $865,991 | -23.4% | 455 | +20 | $1,903 | $2,593,400 | 2 | Warner Bros. | false | false |
| 8 | 5 | Eat Pray Love | $855,554 | -37.8% | 511 | -8 | $1,674 | $12,196,332 | 5 | Sony Pictures Releasing | false | false |
| 9 | 7 | Young Goethe in Love | $692,115 | -27% | 262 | +12 | $2,641 | $2,173,304 | 2 | Warner Bros. | false | false |
| 10 | 8 | Piranha 3D | $501,264 | -41.2% | 320 | +8 | $1,566 | $1,679,465 | 2 | Kinowelt Filmverleih | false | false |
| 11 | 9 | Resident Evil: Afterlife | $325,283 | -39% | 287 | -32 | $1,133 | $15,724,330 | 6 | Constantin Film | false | false |
| 12 | 11 | Single by Contract | $228,885 | -29.9% | 391 | -7 | $585 | $4,737,477 | 6 | Walt Disney Pictures | false | false |
| 13 | 10 | Charlie St. Cloud | $216,139 | -54.9% | 262 | -7 | $824 | $1,958,321 | 3 | Universal Pictures International (UPI) | false | false |
| 14 | 13 | The End Is My Beginning | $187,729 | -13.4% | 88 | +9 | $2,133 | $843,771 | 3 | Universum Film (UFA) | false | false |
| 15 | 12 | Twelve | $143,897 | -55.8% | 111 | - | $1,296 | $679,382 | 2 | TOBIS Film | false | false |
| 16 | 14 | Furry Vengeance | $139,641 | -34.6% | 201 | -5 | $694 | $470,273 | 2 | Concorde Filmverleih | false | false |
| 17 | 17 | The Sandman and the Lost Sand of Dreams | $133,552 | -32.9% | 394 | -8 | $338 | $991,944 | 4 | Falcom Media | false | false |
| 18 | - | Scott Pilgrim vs. the World | $132,831 | - | 79 | - | $1,681 | $194,533 | 1 | Universal Pictures International (UPI) | true | false |
| 19 | 15 | Gainsbourg: A Heroic Life | $130,537 | -36.4% | 97 | -1 | $1,345 | $432,290 | 2 | Prokino Filmverleih | false | false |
| 20 | 19 | Inception | $128,015 | -30.6% | 135 | -30 | $948 | $36,402,211 | 13 | Warner Bros. | false | false |
| 21 | - | Exit Through the Gift Shop | $105,450 | - | 41 | - | $2,571 | $147,002 | 1 | Alamode Film | true | false |
| 22 | 16 | The Town | $94,257 | -53.5% | 168 | -5 | $561 | $2,590,284 | 5 | Warner Bros. | false | false |
| 23 | 18 | The American | $86,841 | -53.3% | 190 | -40 | $457 | $3,660,762 | 6 | TOBIS Film | false | false |
| 24 | - | Ondine | $83,280 | - | 59 | - | $1,411 | $87,307 | 1 | Concorde Filmverleih | true | false |
| 25 | 20 | The Sorcerer's Apprentice | $69,402 | -42.3% | 171 | -56 | $405 | $5,962,935 | 8 | Walt Disney Pictures | false | false |
| 26 | 23 | Little Nicholas | $67,215 | -26.3% | 146 | - | $460 | $1,822,763 | 9 | Central Film | false | false |
| 27 | - | Cehennem 3D | $52,861 | - | 55 | - | $961 | $52,861 | 1 | N/A | true | false |
| 28 | 21 | Vampires Suck | $52,512 | -55.7% | 195 | -115 | $269 | $8,064,054 | 7 | 20th Century Fox International | false | false |
| 29 | 22 | The Last Exorcism | $48,642 | -56.3% | 119 | -74 | $408 | $999,537 | 4 | Kinowelt Filmverleih | false | false |
| 30 | 25 | Ramona and Beezus | $39,806 | -32.8% | 52 | +1 | $765 | $136,292 | 2 | 20th Century Fox International | false | false |
| 31 | 28 | Honey | $37,481 | -18% | 40 | - | $937 | $774,256 | 7 | Piffl Medien | false | false |
| 32 | 26 | Step Up 3D | $37,325 | -26.9% | 62 | -13 | $602 | $13,869,503 | 9 | Constantin Film | false | false |
| 33 | 32 | Diary of a Wimpy Kid | $36,968 | -12.1% | 45 | -7 | $821 | $439,034 | 6 | 20th Century Fox International | false | false |
| 34 | 24 | The Road | $36,742 | -41.9% | 56 | +1 | $656 | $314,013 | 3 | Senator Film | false | false |
| 35 | 27 | Mammuth | $35,280 | -30.7% | 54 | +5 | $653 | $949,861 | 6 | X Verleih AG | false | false |
| 36 | 38 | Avatar | $28,221 | -21.2% | 33 | -5 | $855 | $156,284,974 | 45 | 20th Century Fox International | false | false |
| 37 | 37 | Kinshasa Symphony | $28,067 | -22.6% | 21 | -1 | $1,336 | $243,774 | 5 | N/A | false | false |
| 38 | 30 | The Concert | $27,781 | -34.4% | 110 | -19 | $252 | $3,026,562 | 13 | Concorde Filmverleih | false | false |
| 39 | 35 | Lebanon | $26,031 | -31.3% | 32 | +2 | $813 | $83,586 | 2 | Central Film | false | false |
| 40 | 31 | Jew Suss: Rise and Fall | $24,126 | -42.7% | 79 | -4 | $305 | $795,735 | 5 | Concorde Filmverleih | false | false |
| 41 | 41 | Grown Ups | $12,633 | -48.5% | 55 | -20 | $229 | $18,258,688 | 12 | Sony Pictures Releasing | false | false |
