| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Paranormal Activity 2 | $2,621,408 | - | 185 | - | $14,169 | $2,649,923 | 1 | Paramount Pictures International | true | false |
| 2 | - | Life as We Know It | $1,902,782 | - | 229 | - | $8,309 | $2,011,240 | 1 | Warner Bros. | true | false |
| 3 | 2 | The Town | $1,464,263 | -27.5% | 226 | -34 | $6,479 | $4,148,015 | 2 | Warner Bros. | false | false |
| 4 | 1 | Eat Pray Love | $1,210,081 | -43.7% | 328 | -2 | $3,689 | $9,068,767 | 3 | Sony Pictures Releasing | false | false |
| 5 | 3 | Resident Evil: Afterlife | $800,882 | -57% | 188 | +2 | $4,260 | $3,288,527 | 2 | Sony Pictures Releasing | false | false |
| 6 | - | Les Misérables in Concert: The 25th Anniversary | $332,703 | - | 83 | - | $4,008 | $332,703 | 1 | Rialto Distribution | true | false |
| 7 | 4 | Despicable Me | $296,165 | -44.4% | 233 | -84 | $1,271 | $21,271,801 | 8 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Legend of the Guardians: The Owls of Ga'Hoole | $208,289 | -44% | 166 | -114 | $1,254 | $4,331,769 | 4 | Roadshow Films | false | false |
| 9 | 5 | Let Me In | $195,645 | -52% | 151 | +1 | $1,295 | $733,890 | 2 | Icon Film Distribution | false | false |
| 10 | 13 | The Girl Who Played with Fire | $178,286 | -26.6% | 96 | -3 | $1,857 | $2,457,429 | 5 | Rialto Distribution | false | false |
| 11 | 8 | Wall Street: Money Never Sleeps | $169,625 | -53.3% | 106 | -56 | $1,600 | $5,890,381 | 5 | 20th Century Fox International | false | false |
| 12 | 6 | Dinner for Schmucks | $163,387 | -58.9% | 124 | -72 | $1,317 | $3,158,846 | 4 | Paramount Pictures International | false | false |
| 13 | 9 | Tomorrow, When the War Began | $134,984 | -51.8% | 121 | -47 | $1,115 | $13,052,523 | 8 | Paramount Pictures International | false | false |
| 14 | 11 | The Other Guys | $127,876 | -51.2% | 99 | -39 | $1,291 | $10,128,701 | 7 | Sony Pictures Releasing | false | false |
| 15 | 10 | Easy A | $125,116 | -52.6% | 93 | -25 | $1,345 | $5,577,265 | 6 | Sony Pictures Releasing | false | false |
| 16 | 15 | Diary of a Wimpy Kid | $101,420 | -45.8% | 116 | -53 | $874 | $5,076,181 | 5 | 20th Century Fox International | false | false |
| 17 | 12 | Buried | $96,991 | -61.6% | 100 | -38 | $969 | $1,289,137 | 3 | Icon Film Distribution | false | false |
| 18 | 14 | The Last Airbender | $86,685 | -57.6% | 87 | -65 | $996 | $9,601,631 | 6 | Paramount Pictures International | false | false |
| 19 | 16 | Cats & Dogs: The Revenge of Kitty Galore | $67,236 | -50.5% | 77 | -124 | $873 | $6,340,703 | 6 | Roadshow Films | false | false |
| 20 | - | Summer Coda | $63,254 | - | 24 | - | $2,635 | $77,769 | 1 | Jump Street Films | true | false |
| 21 | - | Jhootha Hi Sahi | $19,465 | - | 11 | - | $1,769 | $19,465 | 1 | Mind Blowing Films | true | false |
| 22 | - | La Danse: The Paris Opera Ballet | $10,475 | - | 4 | - | $2,618 | $10,475 | 1 | Madman Entertainment | true | false |
| 23 | - | Road Kill | $5,964 | - | 7 | - | $852 | $5,964 | 1 | N/A | true | false |
| 24 | - | The Housemaid | $4,337 | - | 1 | - | $4,337 | $4,337 | 1 | Madman Entertainment | true | false |
