| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Eat Pray Love | $26,748 | -25.5% | 6 | - | $4,458 | $142,812 | 3 | Sony Pictures Releasing | false | false |
| 2 | - | Life as We Know It | $18,589 | - | 6 | - | $3,098 | $21,889 | 1 | Warner Bros. | true | false |
| 3 | - | The Social Network | $15,905 | - | 5 | - | $3,181 | $19,061 | 1 | Sony Pictures Releasing | true | false |
| 4 | 3 | Grown Ups | $14,379 | -21.2% | 6 | -1 | $2,396 | $166,057 | 5 | Sony Pictures Releasing | false | false |
| 5 | 2 | The Last Airbender | $14,131 | -34.8% | 7 | -1 | $2,018 | $79,312 | 3 | Paramount Pictures International | false | false |
| 6 | 4 | Legend of the Guardians: The Owls of Ga'Hoole | $11,368 | -21.4% | 7 | -1 | $1,624 | $32,352 | 2 | Warner Bros. | false | false |
| 7 | - | The Expendables | $10,245 | - | 4 | - | $2,561 | $10,245 | 1 | N/A | true | false |
| 8 | 5 | Solitary Man | $9,595 | -33.2% | 4 | - | $2,398 | $27,272 | 2 | N/A | false | false |
| 9 | - | Hachi: A Dog's Tale | $6,974 | - | 4 | - | $1,743 | $9,705 | 1 | N/A | true | false |
| 10 | 8 | Igualita a mí | $5,761 | -42.5% | 3 | -1 | $1,920 | $139,813 | 6 | Walt Disney Pictures | false | false |
| 11 | 7 | Wall Street: Money Never Sleeps | $5,003 | -55.1% | 4 | -2 | $1,250 | $67,707 | 4 | 20th Century Fox International | false | false |
| 12 | 9 | Nanny McPhee Returns | $4,481 | -7.9% | 5 | - | $896 | $29,909 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | 6 | Predators | $3,899 | -66.5% | 4 | -1 | $974 | $20,564 | 2 | 20th Century Fox International | false | false |
| 14 | 11 | Norberto's Deadline | $3,681 | +20.5% | 3 | - | $1,227 | $13,453 | 3 | N/A | false | false |
| 15 | 13 | Nora's Will | $2,541 | +5.4% | 1 | - | $2,541 | $10,164 | 4 | N/A | false | false |
| 16 | 16 | Tinker Bell and the Great Fairy Rescue | $1,988 | +9.7% | 4 | - | $497 | $47,114 | 6 | Walt Disney Pictures | false | false |
| 17 | 10 | Inception | $1,908 | -44.2% | 3 | +1 | $636 | $280,714 | 12 | Warner Bros. | false | false |
| 18 | 14 | Resident Evil: Afterlife | $1,778 | -14.5% | 1 | -2 | $1,778 | $156,728 | 6 | Sony Pictures Releasing | false | false |
| 19 | 17 | Vincere | $1,259 | -22% | 1 | - | $1,259 | $13,410 | 4 | N/A | false | false |
| 20 | 19 | Little Girl | $1,154 | +34.8% | 1 | - | $1,154 | $4,915 | 4 | N/A | false | false |
| 21 | 18 | Seraphine | $751 | -36.1% | 1 | - | $751 | $20,130 | 7 | N/A | false | false |
| 22 | 28 | Pax Americana and the Weaponization of Space | $384 | +200% | 1 | - | $384 | $857 | 2 | N/A | false | false |
| 23 | 24 | Despicable Me | $342 | +80% | 1 | - | $342 | $159,938 | 12 | Universal Pictures International (UPI) | false | false |
| 24 | 23 | Cats & Dogs: The Revenge of Kitty Galore | $192 | -46.8% | 2 | - | $96 | $189,633 | 9 | Warner Bros. | false | false |
| 25 | 25 | Furry Vengeance | $182 | +10.3% | 1 | -1 | $182 | $12,530 | 5 | N/A | false | false |
| 26 | 22 | The Sorcerer's Apprentice | $167 | -59.1% | 1 | - | $167 | $72,117 | 8 | Walt Disney Pictures | false | false |
