| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Expendables | $166,499 | -23.1% | 52 | - | $3,201 | $2,123,084 | 5 | Benelux Film Distributors | false | false |
| 2 | 4 | Inception | $151,169 | -21.9% | 92 | - | $1,643 | $5,086,492 | 9 | Warner Bros. | false | false |
| 3 | 3 | Piranha 3D | $147,265 | -30% | 30 | - | $4,908 | $665,028 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 4 | 1 | Grown Ups | $133,360 | -45.1% | 28 | - | $4,762 | $410,601 | 2 | Sony Pictures Releasing | false | false |
| 5 | 8 | Of Gods and Men | $115,166 | -9.7% | 20 | - | $5,758 | $289,369 | 2 | Benelux Film Distributors | false | false |
| 6 | 7 | Oxygen | $112,491 | -12.4% | 22 | +3 | $5,113 | $272,687 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | 5 | Step Up 3D | $110,534 | -30.2% | 54 | - | $2,046 | $3,028,919 | 7 | Belga Films | false | false |
| 8 | 6 | The Sorcerer's Apprentice | $91,783 | -28.7% | 51 | -7 | $1,799 | $1,688,307 | 6 | Walt Disney Pictures | false | false |
| 9 | - | The Last Exorcism | $89,566 | - | 12 | - | $7,463 | $89,754 | 1 | Cinéart | true | false |
| 10 | - | Tamara Drewe | $66,406 | - | 13 | - | $5,108 | $77,858 | 1 | Cinéart | true | false |
| 11 | 10 | Salt | $64,961 | -24.7% | 36 | -4 | $1,804 | $1,654,416 | 7 | Sony Pictures Releasing | false | false |
| 12 | 9 | Going the Distance | $63,685 | -41% | 30 | - | $2,122 | $238,644 | 2 | Warner Bros. | false | false |
| 13 | 11 | A Turtle's Tale: Sammy's Adventures | $58,146 | -30.2% | 55 | - | $1,057 | $1,571,545 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 14 | 12 | Marmaduke | $57,817 | -28.2% | 48 | - | $1,204 | $854,777 | 5 | 20th Century Fox International | false | false |
| 15 | 13 | The Switch | $51,116 | -26.5% | 28 | -4 | $1,825 | $533,217 | 4 | Paradiso Entertainment | false | false |
| 16 | 14 | The Last Airbender | $37,553 | -37.5% | 38 | -6 | $988 | $2,953,834 | 8 | Universal Pictures International (UPI) | false | false |
| 17 | - | The Disappearance of Alice Creed | $35,747 | - | 12 | - | $2,978 | $46,508 | 1 | Benelux Film Distributors | true | false |
| 18 | 15 | Toy Story 3 | $31,163 | -41.2% | 43 | -7 | $724 | $4,958,878 | 13 | Walt Disney Pictures | false | false |
| 19 | 16 | Shrek Forever After | $29,431 | -31.5% | 50 | +1 | $588 | $4,468,432 | 10 | Universal Pictures International (UPI) | false | false |
| 20 | 18 | Avatar 2010 Special Edition | $24,898 | -40.5% | 14 | - | $1,778 | $75,358 | 2 | 20th Century Fox International | false | false |
| 21 | 17 | Cats & Dogs: The Revenge of Kitty Galore | $24,774 | -42.3% | 59 | -12 | $419 | $1,255,947 | 7 | Warner Bros. | false | false |
| 22 | 19 | Knight and Day 2010 Re-release | $21,299 | -30.3% | 27 | -17 | $788 | $2,261,747 | 8 | 20th Century Fox International | false | false |
| 23 | 20 | Letters to Juliet | $17,598 | -31.7% | 20 | -2 | $879 | $310,810 | 4 | Belga Films | false | false |
| 24 | 23 | The Killer Inside Me | $15,900 | +1.2% | 10 | - | $1,590 | $134,605 | 5 | Paradiso Entertainment | false | false |
| 25 | 22 | The Tree | $15,299 | -37.4% | 11 | - | $1,390 | $170,084 | 4 | Cinéart | false | false |
| 26 | 21 | The Karate Kid | $15,159 | -40.8% | 22 | -3 | $689 | $2,306,779 | 9 | Sony Pictures Releasing | false | false |
| 27 | - | The Runaways | $12,274 | - | 7 | - | $1,753 | $12,274 | 1 | Belga Films | true | false |
| 28 | 24 | Tinker Bell and the Lost Treasure | $9,516 | -38% | 13 | - | $732 | $128,341 | 5 | Walt Disney Pictures | false | false |
| 29 | 27 | Love Crime | $6,579 | -36.7% | 17 | - | $387 | $144,813 | 5 | Benelux Film Distributors | false | false |
| 30 | 29 | The Secret in Their Eyes | $5,544 | -10.2% | 7 | - | $792 | $285,076 | 15 | N/A | false | false |
| 31 | 28 | Uncle Boonmee Who Can Recall His Past Lives | $5,504 | -34.3% | 8 | - | $688 | $36,342 | 3 | N/A | false | false |
| 32 | 25 | The Twilight Saga: Eclipse | $5,472 | -61.1% | 14 | -2 | $390 | $6,255,171 | 12 | Belga Films | false | false |
| 33 | - | Single by Contract | $5,452 | - | 4 | - | $1,363 | $5,452 | 1 | N/A | true | false |
| 34 | 26 | Solutions locales pour un désordre global | $4,800 | -65.1% | 6 | - | $800 | $27,327 | 2 | N/A | false | false |
| 35 | 42 | The Double Hour | $4,274 | +287.1% | 5 | - | $854 | $18,262 | 2 | ABC Distribution | false | false |
| 36 | 30 | The Italian | $3,717 | -32.6% | 10 | - | $371 | $341,811 | 10 | Alternative Films | false | false |
| 37 | 32 | Women Without Men | $2,787 | -35.4% | 3 | - | $929 | $16,525 | 3 | Benelux Film Distributors | false | false |
| 38 | - | The Odd One Out | $2,666 | - | 4 | - | $666 | $2,666 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 39 | 36 | Furry Vengeance | $2,648 | -12.2% | 6 | - | $441 | $185,540 | 9 | Belga Films | false | false |
| 40 | 37 | The Fourth Kind | $2,235 | -13.9% | 4 | - | $558 | $99,853 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 41 | 31 | Ondine | $2,165 | -55.1% | 4 | - | $541 | $31,265 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 42 | - | Come Undone | $2,046 | - | 6 | - | $341 | $48,811 | 6 | ABC Distribution | false | false |
| 43 | 39 | Law Abiding Citizen | $1,800 | -12% | 1 | - | $1,800 | $463,009 | 16 | Belga Films | false | false |
| 44 | 40 | The Last Station 2010 Re-release | $1,666 | -0.9% | 4 | +1 | $416 | $53,943 | 14 | Belga Films | false | false |
| 45 | 41 | Get Him to the Greek | $1,509 | -1.2% | 3 | - | $503 | $55,546 | 5 | Universal Pictures International (UPI) | false | false |
| 46 | 44 | The Ghost Writer | $1,171 | +112.9% | 3 | - | $390 | $851,635 | 26 | Benelux Film Distributors | false | false |
| 47 | 47 | The Blonde with Bare Breasts | $464 | +32.6% | 6 | - | $77 | $6,109 | 4 | Benelux Film Distributors | false | false |
| 48 | 48 | The Illusionist | $443 | +171.8% | 3 | +2 | $147 | $57,223 | 14 | Paradiso Entertainment | false | false |
