| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Grown Ups | $242,871 | - | 28 | - | $8,673 | $249,382 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | The Expendables | $216,482 | -13.4% | 52 | - | $4,163 | $1,916,059 | 4 | Benelux Film Distributors | false | false |
| 3 | 2 | Piranha 3D | $210,319 | -10.5% | 30 | +1 | $7,010 | $487,503 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 4 | 3 | Inception | $193,602 | +1.1% | 92 | - | $2,104 | $4,896,708 | 8 | Warner Bros. | false | false |
| 5 | 4 | Step Up 3D | $158,328 | -7.8% | 54 | -3 | $2,932 | $2,894,995 | 6 | Belga Films | false | false |
| 6 | 5 | The Sorcerer's Apprentice | $128,777 | -4.8% | 58 | -5 | $2,220 | $1,576,172 | 5 | Walt Disney Pictures | false | false |
| 7 | - | Oxygen | $128,394 | - | 19 | - | $6,757 | $130,130 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 8 | - | Of Gods and Men | $127,560 | - | 20 | - | $6,378 | $134,237 | 1 | Benelux Film Distributors | true | false |
| 9 | - | Going the Distance | $108,013 | - | 30 | - | $3,600 | $151,405 | 1 | Warner Bros. | true | false |
| 10 | 7 | Salt | $86,307 | -15.9% | 40 | -6 | $2,157 | $1,573,619 | 6 | Sony Pictures Releasing | false | false |
| 11 | 10 | A Turtle's Tale: Sammy's Adventures | $83,334 | +54% | 55 | -5 | $1,515 | $1,509,060 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 12 | 9 | Marmaduke | $80,471 | +36.5% | 48 | - | $1,676 | $794,810 | 4 | 20th Century Fox International | false | false |
| 13 | 6 | The Switch | $69,571 | -33.8% | 32 | - | $2,174 | $467,701 | 3 | Paradiso Entertainment | false | false |
| 14 | 8 | The Last Airbender | $60,084 | -16.1% | 44 | -12 | $1,365 | $2,910,040 | 7 | Universal Pictures International (UPI) | false | false |
| 15 | 14 | Toy Story 3 | $53,033 | +46.1% | 50 | -13 | $1,060 | $4,911,756 | 12 | Walt Disney Pictures | false | false |
| 16 | 13 | Shrek Forever After | $42,992 | +5.5% | 49 | -25 | $877 | $4,436,956 | 9 | Universal Pictures International (UPI) | false | false |
| 17 | 17 | Cats & Dogs: The Revenge of Kitty Galore | $42,913 | +49% | 71 | +4 | $604 | $1,229,412 | 6 | Warner Bros. | false | false |
| 18 | - | Avatar 2010 Special Edition | $41,832 | - | 14 | - | $2,988 | $41,832 | 1 | 20th Century Fox International | true | false |
| 19 | 12 | Knight and Day 2010 Re-release | $30,561 | -36.4% | 44 | -27 | $694 | $2,236,159 | 7 | 20th Century Fox International | false | false |
| 20 | 11 | Letters to Juliet | $25,782 | -49.5% | 22 | -7 | $1,171 | $286,714 | 3 | Belga Films | false | false |
| 21 | 15 | The Karate Kid | $25,599 | -26.9% | 25 | -12 | $1,023 | $2,290,439 | 8 | Sony Pictures Releasing | false | false |
| 22 | 16 | The Tree | $24,422 | -22.3% | 11 | -1 | $2,220 | $149,199 | 3 | Cinéart | false | false |
| 23 | 20 | The Killer Inside Me | $15,705 | +3.6% | 10 | - | $1,570 | $114,269 | 4 | Paradiso Entertainment | false | false |
| 24 | 23 | Tinker Bell and the Lost Treasure | $15,344 | +61.5% | 13 | -3 | $1,180 | $117,945 | 4 | Walt Disney Pictures | false | false |
| 25 | 18 | The Twilight Saga: Eclipse | $14,053 | -44.8% | 16 | -8 | $878 | $6,247,462 | 11 | Belga Films | false | false |
| 26 | - | Solutions locales pour un désordre global | $13,757 | - | 6 | - | $2,292 | $18,600 | 1 | N/A | true | false |
| 27 | 19 | Love Crime | $10,396 | -39.7% | 17 | - | $611 | $133,232 | 4 | Benelux Film Distributors | false | false |
| 28 | 21 | Uncle Boonmee Who Can Recall His Past Lives | $8,376 | -38.5% | 8 | - | $1,047 | $28,405 | 2 | N/A | false | false |
| 29 | 26 | The Secret in Their Eyes | $6,173 | -18.1% | 7 | - | $881 | $277,600 | 14 | N/A | false | false |
| 30 | 30 | The Italian | $5,512 | +28.7% | 10 | +1 | $551 | $336,847 | 9 | Alternative Films | false | false |
| 31 | 28 | Ondine | $4,820 | -20.5% | 4 | - | $1,205 | $28,049 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 29 | Women Without Men | $4,313 | -14.2% | 3 | - | $1,437 | $12,531 | 2 | Benelux Film Distributors | false | false |
| 33 | - | The Clink of Ice | $3,925 | - | 13 | - | $301 | $3,925 | 1 | N/A | true | false |
| 34 | 22 | Copacabana Palace 2010 Re-release | $3,845 | -62.9% | 9 | -2 | $427 | $139,568 | 5 | Cinéart | false | false |
| 35 | 24 | With Love... from the Age of Reason | $3,576 | -59.9% | 9 | -4 | $397 | $186,128 | 6 | Cinéart | false | false |
| 36 | 38 | Furry Vengeance | $3,015 | +159% | 6 | - | $502 | $182,679 | 8 | Belga Films | false | false |
| 37 | 33 | The Fourth Kind | $2,595 | +1.2% | 4 | -1 | $648 | $96,898 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 38 | 27 | Killers | $2,444 | -63.5% | 5 | - | $488 | $1,008,073 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 39 | 34 | Law Abiding Citizen | $2,046 | +1.3% | 1 | - | $2,046 | $460,913 | 15 | Belga Films | false | false |
| 40 | 36 | The Last Station 2010 Re-release | $1,681 | +37.2% | 3 | -1 | $560 | $51,233 | 13 | Belga Films | false | false |
| 41 | 31 | Get Him to the Greek | $1,528 | -61.5% | 3 | -4 | $509 | $53,831 | 4 | Universal Pictures International (UPI) | false | false |
| 42 | - | The Double Hour | $1,104 | - | 5 | - | $220 | $1,104 | 1 | ABC Distribution | true | false |
| 43 | 35 | L'autre monde 2010 Re-release | $871 | -46.8% | 7 | -1 | $124 | $26,165 | 4 | N/A | false | false |
| 44 | 40 | The Ghost Writer | $550 | -20.6% | 3 | - | $183 | $850,464 | 25 | Benelux Film Distributors | false | false |
| 45 | 25 | In Gold We Trust | $509 | -93.6% | 2 | -6 | $254 | $41,912 | 3 | Les Films de l'Elysée | false | false |
| 46 | 32 | Beyond Suspicion | $391 | -89.3% | 2 | - | $195 | $5,344 | 2 | N/A | false | false |
| 47 | 37 | The Blonde with Bare Breasts | $350 | -70.8% | 6 | - | $58 | $5,504 | 3 | Benelux Film Distributors | false | false |
| 48 | 39 | The Illusionist | $163 | -79.7% | 1 | -3 | $163 | $56,281 | 13 | Paradiso Entertainment | false | false |
| 49 | 43 | Greenberg | $82 | +22.4% | 1 | - | $82 | $47,966 | 14 | Benelux Film Distributors | false | false |
