| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Last Airbender | $1,048,898 | - | 84 | - | $12,486 | $1,052,660 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | - | The Expendables | $618,326 | - | 88 | - | $7,026 | $705,714 | 1 | Benelux Film Distributors | true | false |
| 3 | 2 | Step Up 3D | $440,852 | -29.1% | 92 | +3 | $4,791 | $2,809,313 | 3 | Independent Films | false | false |
| 4 | 1 | Inception | $420,148 | -37.2% | 103 | - | $4,079 | $6,345,820 | 5 | Warner Bros. | false | false |
| 5 | 3 | Salt | $267,387 | -45.2% | 80 | - | $3,342 | $1,999,345 | 3 | Sony Pictures Releasing | false | false |
| 6 | 4 | Shrek Forever After | $152,814 | -54.8% | 155 | -45 | $985 | $6,279,335 | 7 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | Marmaduke | $144,703 | -53.8% | 77 | - | $1,879 | $782,004 | 2 | Warner Bros. | false | false |
| 8 | 6 | Toy Story 3 | $138,445 | -43.2% | 126 | -4 | $1,098 | $5,060,414 | 9 | Walt Disney Pictures | false | false |
| 9 | 7 | The Karate Kid | $104,846 | -51.8% | 82 | -3 | $1,278 | $3,453,754 | 5 | Sony Pictures Releasing | false | false |
| 10 | 8 | A Turtle's Tale: Sammy's Adventures | $99,011 | -54.4% | 93 | - | $1,064 | $1,093,699 | 3 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | The Sorcerer's Apprentice | $90,048 | -55.2% | 91 | -4 | $989 | $1,634,553 | 4 | Walt Disney Pictures | false | false |
| 12 | - | Sterke verhalen | $85,597 | - | 32 | - | $2,674 | $99,098 | 1 | A-Film Distribution | true | false |
| 13 | 10 | Knight and Day 2010 Re-release | $82,659 | -48.3% | 78 | -22 | $1,059 | $2,945,883 | 6 | Warner Bros. | false | false |
| 14 | 11 | Cats & Dogs: The Revenge of Kitty Galore | $58,015 | -48.5% | 93 | -1 | $623 | $1,032,973 | 4 | Warner Bros. | false | false |
| 15 | 12 | The Joneses | $33,435 | -52.4% | 17 | -1 | $1,966 | $161,706 | 2 | Benelux Film Distributors | false | false |
| 16 | 14 | The Twilight Saga: Eclipse | $25,830 | -46.3% | 27 | -18 | $956 | $3,655,885 | 8 | Independent Films | false | false |
| 17 | - | Love Crime | $19,804 | - | 11 | - | $1,800 | $23,910 | 1 | Benelux Film Distributors | true | false |
| 18 | 13 | Predators | $19,784 | -68% | 25 | -18 | $791 | $628,853 | 4 | Warner Bros. | false | false |
| 19 | 15 | Certified Copy | $18,387 | -45.8% | 10 | +1 | $1,838 | $134,217 | 3 | Wild Bunch Distribution | false | false |
| 20 | - | Me Too | $10,118 | - | 13 | - | $778 | $409,858 | 15 | A-Film Distribution | false | false |
