| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Inception | $1,329,772 | - | 101 | - | $13,166 | $1,329,772 | 1 | Warner Bros. | true | false |
| 2 | - | The Karate Kid | $775,976 | - | 84 | - | $9,237 | $1,273,098 | 1 | Sony Pictures Releasing | true | false |
| 3 | 1 | Shrek Forever After | $704,996 | -19.1% | 233 | +3 | $3,025 | $3,395,257 | 3 | Universal Pictures International (UPI) | false | false |
| 4 | 2 | Knight and Day 2010 Re-release | $500,256 | -33.9% | 107 | +1 | $4,675 | $1,531,824 | 2 | Warner Bros. | false | false |
| 5 | 3 | Toy Story 3 | $438,275 | -10.9% | 175 | -13 | $2,504 | $3,007,423 | 5 | Walt Disney Pictures | false | false |
| 6 | 4 | The Twilight Saga: Eclipse | $200,601 | -38.5% | 102 | -3 | $1,966 | $3,157,445 | 4 | Independent Films | false | false |
| 7 | 5 | Sex and the City 2 | $58,280 | -39% | 54 | -36 | $1,079 | $4,978,453 | 9 | Warner Bros. | false | false |
| 8 | 6 | Unthinkable | $52,281 | -34.9% | 25 | -1 | $2,091 | $329,243 | 3 | A-Film Distribution | false | false |
| 9 | 7 | Get Him to the Greek | $43,103 | -39.1% | 24 | -15 | $1,795 | $441,410 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | 10 | Furry Vengeance | $37,084 | -17.1% | 66 | - | $561 | $120,261 | 2 | Entertainment One | false | false |
| 11 | 9 | Letters to Juliet | $31,743 | -33.8% | 32 | -13 | $991 | $626,193 | 6 | Entertainment One | false | false |
| 12 | 12 | The Back-up Plan | $22,356 | -32.9% | 18 | -8 | $1,242 | $632,545 | 6 | Sony Pictures Releasing | false | false |
| 13 | 8 | The A-Team | $22,093 | -58.6% | 29 | -33 | $761 | $1,553,398 | 7 | Warner Bros. | false | false |
| 14 | 11 | Killers | $20,912 | -47.2% | 19 | -23 | $1,100 | $1,250,514 | 8 | A-Film Distribution | false | false |
| 15 | 13 | Prince of Persia: The Sands of Time | $18,162 | -44.1% | 20 | -6 | $908 | $2,547,312 | 10 | Walt Disney Pictures | false | false |
| 16 | 14 | Leap Year | $16,191 | -33.3% | 10 | - | $1,619 | $117,142 | 3 | Universal Pictures International (UPI) | false | false |
| 17 | 17 | The Ghost Writer | $16,160 | -16.5% | 16 | +7 | $1,010 | $557,979 | 10 | Benelux Film Distributors | false | false |
| 18 | 15 | Greenberg | $15,218 | -36.1% | 6 | - | $2,536 | $71,348 | 3 | Benelux Film Distributors | false | false |
| 19 | 16 | Robin Hood | $14,556 | -26.3% | 11 | -2 | $1,323 | $3,647,474 | 11 | Universal Pictures International (UPI) | false | false |
| 20 | 18 | Me Too | $13,178 | -11.1% | 13 | - | $1,013 | $319,132 | 11 | A-Film Distribution | false | false |
| 21 | - | The Illusionist | $8,763 | - | 3 | - | $2,921 | $8,763 | 1 | Paradiso Entertainment | true | false |
| 22 | - | White Material | $6,851 | - | 4 | - | $1,712 | $6,851 | 1 | Wild Bunch Distribution | true | false |
| 23 | - | Raise Your Head | $2,809 | - | 6 | - | $468 | $2,809 | 1 | Cinemien | true | false |
| 24 | - | Exam | $262 | - | 1 | - | $262 | $262 | 1 | Benelux Film Distributors | true | false |
