| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Back-up Plan | $14,688 | - | 4 | - | $3,672 | $14,688 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Iron Man 2 | $13,597 | -61.4% | 6 | - | $2,266 | $74,510 | 2 | Paramount Pictures International | false | false |
| 3 | 3 | Clash of the Titans | $6,279 | -42.4% | 6 | - | $1,046 | $127,783 | 4 | - | false | false |
| 4 | 5 | How to Train Your Dragon | $5,109 | -38.6% | 11 | - | $464 | $208,249 | 6 | - | false | false |
| 5 | 2 | When in Rome | $4,910 | -55.6% | 2 | - | $2,455 | $25,831 | 2 | - | false | false |
| 6 | 4 | Burnt by the Sun 2 | $3,577 | -65.8% | 4 | - | $894 | $56,119 | 3 | - | false | false |
| 7 | 6 | Date Night | $3,303 | -43.8% | 5 | - | $660 | $71,297 | 5 | - | false | false |
| 8 | 8 | Alice in Wonderland | $2,795 | -20.2% | 7 | - | $399 | $352,610 | 10 | - | false | false |
| 9 | 7 | Hot Tub Time Machine | $2,363 | -53.6% | 2 | - | $1,181 | $44,135 | 4 | ACME | false | false |
| 10 | 13 | Avatar | $1,798 | +1.6% | 8 | - | $224 | $1,329,570 | 21 | 20th Century Fox International | false | false |
| 11 | 9 | Nanny McPhee Returns | $1,733 | -37% | 2 | - | $866 | $15,117 | 3 | - | false | false |
| 12 | 11 | Remember Me | $1,525 | -37% | 2 | - | $762 | $64,300 | 7 | ACME | false | false |
| 13 | - | Zero 2 | $685 | - | 1 | - | $685 | $685 | 1 | N/A | true | false |
| 14 | 14 | Oceans | $657 | -45.9% | 1 | - | $657 | $23,717 | 6 | ACME | false | false |
| 15 | 12 | Bad Lieutenant: Port of Call New Orleans | $559 | -71.3% | 1 | - | $559 | $10,476 | 3 | N/A | false | false |
| 16 | 10 | The Bounty Hunter | $77 | -96.9% | 5 | - | $15 | $122,884 | 7 | Sony Pictures Releasing | false | false |
