| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Happy Housewife | $453,238 | +5.5% | 118 | -1 | $3,841 | $2,888,509 | 4 | Benelux Film Distributors | false | false |
| 2 | 1 | Iron Man 2 | $398,797 | -42.9% | 82 | -1 | $4,863 | $1,564,046 | 2 | Paramount Pictures International | false | false |
| 3 | - | Date Night | $367,641 | - | 70 | - | $5,252 | $372,322 | 1 | Warner Bros. | true | false |
| 4 | 3 | How to Train Your Dragon | $308,875 | +34.4% | 126 | - | $2,451 | $2,709,747 | 6 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Alice in Wonderland | $214,784 | -0.7% | 110 | -25 | $1,952 | $8,901,912 | 9 | Walt Disney Pictures | false | false |
| 6 | 7 | Vicky the Viking | $198,692 | +33.4% | 110 | - | $1,806 | $610,177 | 3 | Independent Films | false | false |
| 7 | 5 | Clash of the Titans | $142,773 | -30% | 78 | -11 | $1,830 | $2,108,604 | 5 | Warner Bros. | false | false |
| 8 | 11 | Nanny McPhee Returns | $127,638 | +68.1% | 97 | -1 | $1,315 | $1,133,124 | 7 | Universal Pictures International (UPI) | false | false |
| 9 | 6 | Kick-Ass | $118,465 | -34.8% | 91 | -10 | $1,301 | $1,093,780 | 4 | A-Film Distribution | false | false |
| 10 | 8 | Green Zone 2010 Re-release | $118,044 | -16.3% | 50 | - | $2,360 | $872,034 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | 10 | The Bounty Hunter | $66,758 | -28% | 50 | - | $1,335 | $1,351,758 | 6 | Sony Pictures Releasing | false | false |
| 12 | 9 | I Love You Phillip Morris | $61,478 | -45.2% | 40 | -1 | $1,536 | $404,848 | 3 | Independent Films | false | false |
| 13 | 15 | Planet 51 | $49,942 | +17.8% | 46 | - | $1,085 | $158,678 | 2 | Independent Films | false | false |
| 14 | 13 | Fantastic Mr. Fox | $41,169 | -6.3% | 15 | - | $2,744 | $117,297 | 2 | 20th Century Fox International | false | false |
| 15 | 12 | Avatar | $40,898 | -12.3% | 16 | - | $2,556 | $23,945,890 | 21 | 20th Century Fox International | false | false |
| 16 | - | Toy Story 2009 Re-release | $31,296 | - | 45 | - | $695 | $47,885 | 1 | Walt Disney Pictures | true | false |
| 17 | 14 | The Crazies | $30,492 | -30.1% | 28 | -7 | $1,089 | $218,280 | 3 | A-Film Distribution | false | false |
| 18 | - | 22 Bullets | $28,270 | - | 13 | - | $2,174 | $52,932 | 1 | Entertainment One | true | false |
| 19 | - | Eep! 2010 Re-release | $26,788 | - | 43 | - | $622 | $1,713,357 | 12 | Independent Films | false | false |
| 20 | 16 | The Girl Who Kicked the Hornet's Nest | $26,237 | -27.1% | 27 | -4 | $971 | $695,039 | 7 | Benelux Film Distributors | false | false |
