| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Clash of the Titans | $40,182 | -45.4% | 8 | -1 | $5,022 | $144,169 | 2 | Warner Bros. | false | false |
| 2 | - | Shutter Island | $28,130 | - | 7 | - | $4,018 | $28,130 | 1 | Paramount Pictures International | true | false |
| 3 | - | Date Night | $22,241 | - | 7 | - | $3,177 | $22,241 | 1 | 20th Century Fox International | true | false |
| 4 | 5 | How to Train Your Dragon | $11,438 | -5.7% | 7 | -1 | $1,634 | $180,841 | 5 | Paramount Pictures International | false | false |
| 5 | 4 | Alice in Wonderland | $10,227 | -18.9% | 7 | - | $1,461 | $487,744 | 8 | Walt Disney Pictures | false | false |
| 6 | 2 | The Bounty Hunter | $8,539 | -47.2% | 5 | - | $1,707 | $111,971 | 5 | Sony Pictures Releasing | false | false |
| 7 | 3 | Night Runner | $7,674 | -40.8% | 5 | - | $1,534 | $43,967 | 3 | N/A | false | false |
| 8 | 7 | The Wave | $7,332 | -3.2% | 4 | - | $1,833 | $19,166 | 2 | N/A | false | false |
| 9 | 6 | La despedida | $6,140 | -35.1% | 2 | -3 | $3,070 | $92,216 | 5 | N/A | false | false |
| 10 | 8 | Everybody's Fine | $4,438 | -40.3% | 5 | - | $887 | $40,577 | 4 | Walt Disney Pictures | false | false |
| 11 | 12 | Edge of Darkness | $2,273 | -36% | 1 | - | $2,273 | $126,138 | 9 | Warner Bros. | false | false |
| 12 | 14 | The Blind Side | $2,183 | -14.1% | 1 | - | $2,183 | $75,740 | 8 | Warner Bros. | false | false |
| 13 | 9 | The Book of Eli | $1,971 | -70.6% | 4 | -1 | $492 | $105,058 | 6 | Sony Pictures Releasing | false | false |
| 14 | 17 | Hiroshima | $1,937 | -6.6% | 1 | - | $1,937 | $4,011 | 2 | N/A | false | false |
| 15 | 16 | Away We Go | $1,659 | -24.1% | 1 | - | $1,659 | $6,812 | 3 | Universal Pictures International (UPI) | false | false |
| 16 | 15 | The Widows of Thursdays | $1,244 | -44.5% | 1 | - | $1,244 | $73,618 | 8 | N/A | false | false |
| 17 | - | A Prophet | $936 | - | 1 | - | $936 | $936 | 1 | Sony Pictures Releasing | true | false |
| 18 | 21 | Saw VI | $878 | -28.6% | 1 | - | $878 | $21,763 | 5 | Walt Disney Pictures | false | false |
| 19 | 11 | The Men Who Stare at Goats | $836 | -77.9% | 2 | - | $418 | $14,880 | 3 | Sony Pictures Releasing | false | false |
| 20 | 10 | The Last Deadly Mission | $723 | -83.5% | 3 | -1 | $241 | $6,439 | 2 | N/A | false | false |
| 21 | 18 | The Secret in Their Eyes | $545 | -66.8% | 1 | -1 | $545 | $397,437 | 28 | N/A | false | false |
| 22 | 19 | Let it Rain | $395 | -74.4% | 1 | -1 | $395 | $15,072 | 6 | N/A | false | false |
| 23 | 13 | Daybreakers | $279 | -91.6% | 1 | -2 | $279 | $4,879 | 2 | N/A | false | false |
| 24 | 25 | Alvin and the Chipmunks: The Squeakquel | $271 | -9.4% | 1 | - | $271 | $174,428 | 17 | 20th Century Fox International | false | false |
| 25 | 20 | Tooth Fairy | $249 | -80.4% | 1 | -2 | $249 | $73,077 | 9 | 20th Century Fox International | false | false |
| 26 | 24 | Igor | $152 | -64% | 1 | - | $152 | $4,663 | 5 | N/A | false | false |
| 27 | 23 | A Serious Man | $103 | -83.2% | 1 | - | $103 | $25,622 | 9 | Universal Pictures International (UPI) | false | false |
