| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Clash of the Titans | $103,079 | - | 8 | - | $12,884 | $103,079 | 1 | Warner Bros. | true | false |
| 2 | 2 | The Bounty Hunter | $18,831 | -26.7% | 6 | - | $3,138 | $178,274 | 4 | Sony Pictures Releasing | false | false |
| 3 | 1 | Alice in Wonderland | $15,256 | -41.4% | 6 | - | $2,542 | $415,344 | 7 | Walt Disney Pictures | false | false |
| 4 | 5 | Remember Me | $13,700 | -19.4% | 6 | - | $2,283 | $65,825 | 3 | Jaguar Film International Distribution | false | false |
| 5 | 4 | Date Night | $12,986 | -32.2% | 7 | - | $1,855 | $37,575 | 2 | 20th Century Fox International | false | false |
| 6 | 3 | How to Train Your Dragon | $12,736 | -45.7% | 7 | - | $1,819 | $114,730 | 4 | United International Pictures | false | false |
| 7 | 6 | The Last Song | $12,645 | -24.2% | 5 | - | $2,529 | $62,800 | 3 | Walt Disney Pictures | false | false |
| 8 | 7 | Green Zone | $9,250 | -32.5% | 6 | -2 | $1,541 | $148,257 | 5 | United International Pictures | false | false |
| 9 | 9 | The Hurt Locker | $5,958 | -44.6% | 3 | - | $1,986 | $19,688 | 2 | N/A | false | false |
| 10 | 8 | Tooth Fairy | $5,512 | -50.4% | 6 | - | $918 | $40,694 | 3 | 20th Century Fox International | false | false |
| 11 | 10 | Shutter Island | $4,451 | -54.2% | 3 | -1 | $1,483 | $160,913 | 6 | United International Pictures | false | false |
| 12 | - | Love N' Dancing | $4,370 | - | 3 | - | $1,456 | $4,370 | 1 | N/A | true | false |
| 13 | 13 | Dorian Gray | $4,238 | -11.4% | 1 | - | $4,238 | $24,537 | 3 | Prime Pictures | false | false |
| 14 | 16 | Avatar | $2,590 | -10.8% | 1 | - | $2,590 | $1,689,625 | 18 | 20th Century Fox International | false | false |
| 15 | 15 | My Name Is Khan | $2,545 | -20.4% | 3 | - | $848 | $54,525 | 6 | 20th Century Fox International | false | false |
| 16 | 12 | Arthur and the Revenge of Maltazard | $1,996 | -62.7% | 5 | -1 | $399 | $15,411 | 3 | Walt Disney Pictures | false | false |
| 17 | 11 | Dear John | $1,038 | -80.7% | 1 | -1 | $1,038 | $39,316 | 4 | N/A | false | false |
| 18 | 17 | When in Rome | $977 | -58.9% | 4 | - | $244 | $109,927 | 8 | Walt Disney Pictures | false | false |
| 19 | 19 | The Spy Next Door 2010 Re-release | $944 | -9% | 1 | - | $944 | $46,732 | 6 | N/A | false | false |
| 20 | 18 | From Paris with Love | $623 | -51.3% | 3 | - | $207 | $175,429 | 9 | Italian International Film | false | false |
| 21 | 20 | The Burning Plain | $521 | -38.8% | 2 | - | $260 | $15,842 | 5 | N/A | false | false |
| 22 | 21 | Agora | $396 | -34.4% | 2 | - | $198 | $133,182 | 16 | Italian International Film | false | false |
| 23 | 22 | Siraj El Wadi | $103 | -57.6% | 1 | - | $103 | $72,713 | 24 | Italian International Film | false | false |
| 24 | 25 | In the Loop | $47 | -21.7% | 1 | - | $47 | $2,739 | 7 | N/A | false | false |
| 25 | 24 | The Last Flight | $43 | -28.3% | 1 | - | $43 | $5,299 | 7 | N/A | false | false |
| 26 | 23 | Old Dogs | $41 | -81.9% | 1 | - | $41 | $172,031 | 21 | Walt Disney Pictures | false | false |
