| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | How to Train Your Dragon | $148,208 | -37% | 46 | +1 | $3,221 | $835,062 | 3 | United International Pictures | false | false |
| 2 | - | Date Night | $64,161 | - | 25 | - | $2,566 | $64,161 | 1 | 20th Century Fox International | true | false |
| 3 | 3 | The Wolfman | $62,499 | -33.7% | 30 | - | $2,083 | $216,112 | 2 | United International Pictures | false | false |
| 4 | 2 | Alice in Wonderland | $55,852 | -50.1% | 29 | -24 | $1,925 | $2,228,050 | 6 | Walt Disney Pictures | false | false |
| 5 | - | It's Complicated | $23,430 | - | 15 | - | $1,562 | $23,430 | 1 | United International Pictures | true | false |
| 6 | 5 | [Rec]² | $14,663 | -46.2% | 7 | - | $2,094 | $61,851 | 2 | N/A | false | false |
| 7 | 8 | The Hurt Locker | $7,820 | -49% | 4 | - | $1,955 | $30,415 | 2 | N/A | false | false |
| 8 | - | Big Stan | $7,750 | - | 9 | - | $861 | $57,348 | 14 | - | false | false |
| 9 | 4 | Did You Hear About the Morgans? | $6,928 | -75.9% | 18 | -3 | $384 | $112,378 | 3 | Sony Pictures Releasing | false | false |
| 10 | - | An Education | $5,686 | - | 6 | - | $947 | $5,686 | 1 | Sony Pictures Releasing | true | false |
| 11 | 6 | Edge of Darkness | $5,678 | -75.9% | 14 | - | $405 | $100,904 | 3 | - | false | false |
| 12 | 9 | Invictus | $5,103 | -48.1% | 6 | - | $850 | $41,008 | 8 | - | false | false |
| 13 | 7 | The Book of Eli | $4,710 | -73.1% | 19 | - | $247 | $181,820 | 4 | Sony Pictures Releasing | false | false |
| 14 | 10 | The Blind Side | $1,352 | -81.1% | 7 | -6 | $193 | $118,378 | 5 | - | false | false |
| 15 | 14 | Old Dogs | $1,028 | -25.7% | 14 | - | $73 | $633,399 | 9 | Walt Disney Pictures | false | false |
| 16 | 11 | Over Her Dead Body | $977 | -71.5% | 3 | -1 | $325 | $78,873 | 15 | - | false | false |
| 17 | 15 | Percy Jackson & the Olympians: The Lightning Thief | $844 | -31.9% | 5 | -5 | $168 | $569,073 | 9 | 20th Century Fox International | false | false |
| 18 | 17 | Tooth Fairy | $595 | -29.3% | 8 | -2 | $74 | $709,190 | 11 | 20th Century Fox International | false | false |
| 19 | 12 | Armored | $30 | -99% | 1 | -11 | $30 | $94,575 | 5 | Sony Pictures Releasing | false | false |
| 20 | 16 | Nine | $26 | -97.6% | 2 | -4 | $13 | $53,150 | 11 | Sony Pictures Releasing | false | false |
