| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 2 | - | Hot Tub Time Machine | $19,669 | - | 4 | - | $4,917 | $32,963 | 1 | N/A | true | false |
| 3 | - | I Love You Phillip Morris | $12,474 | - | 3 | - | $4,158 | $21,563 | 1 | N/A | true | false |
| 1 | - | How to Train Your Dragon | $32,318 | - | 9 | - | $3,590 | $50,592 | 1 | United International Pictures | true | false |
| 4 | 2 | King's Road | $7,147 | -43.3% | 3 | - | $2,382 | $35,815 | 2 | N/A | false | false |
| 10 | 8 | The Girl Who Kicked the Hornet's Nest | $1,595 | -56.6% | 1 | -2 | $1,595 | $173,192 | 7 | N/A | false | false |
| 12 | 10 | The Blind Side | $1,421 | -54.6% | 1 | -1 | $1,421 | $42,024 | 4 | Warner Bros. | false | false |
| 5 | 1 | The Bounty Hunter | $4,011 | -69.7% | 3 | -1 | $1,337 | $71,671 | 3 | Sony Pictures Releasing | false | false |
| 6 | - | Dear John | $3,784 | - | 3 | - | $1,261 | $6,638 | 1 | N/A | true | false |
| 8 | 3 | Alice in Wonderland | $3,553 | -66.8% | 3 | -3 | $1,184 | $206,972 | 5 | Walt Disney Pictures | false | false |
| 7 | 5 | Nanny McPhee Returns | $3,718 | -23.5% | 4 | - | $929 | $15,202 | 2 | United International Pictures | false | false |
| 16 | 14 | Daybreakers | $814 | -61.2% | 1 | -1 | $814 | $12,484 | 3 | N/A | false | false |
| 17 | 9 | Shutter Island | $812 | -74.2% | 1 | -2 | $812 | $118,955 | 6 | United International Pictures | false | false |
| 11 | 6 | The Men Who Stare at Goats | $1,495 | -67.9% | 2 | - | $747 | $11,327 | 2 | N/A | false | false |
| 9 | 4 | When in Rome | $2,155 | -62.2% | 3 | - | $718 | $14,312 | 2 | Walt Disney Pictures | false | false |
| 13 | 7 | Green Zone | $1,389 | -67.3% | 2 | -1 | $694 | $62,305 | 4 | United International Pictures | false | false |
| 19 | 15 | Earth | $659 | -59.5% | 1 | - | $659 | $3,654 | 2 | N/A | false | false |
| 14 | 12 | The Good Heart | $1,055 | -58.7% | 2 | - | $527 | $28,042 | 5 | N/A | false | false |
| 15 | 13 | The Lovely Bones | $885 | -59.9% | 2 | - | $442 | $11,183 | 3 | United International Pictures | false | false |
| 18 | 11 | Avatar | $683 | -74.4% | 2 | - | $341 | $1,128,859 | 16 | 20th Century Fox International | false | false |
| 20 | 16 | Cloudy with a Chance of Meatballs | $536 | -65.2% | 2 | - | $268 | $90,746 | 10 | Sony Pictures Releasing | false | false |
