| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | How to Train Your Dragon | $43,300,000 | $43,732,319 | +$432,319 | +1% | 4,055 | - | $43,732,319 | 1 | DreamWorks | - |
| 2 | 2 | - | Alice in Wonderland | $17,300,000 | $17,707,858 | +$407,858 | +2.4% | 3,384 | $293,100,000 | $293,534,935 | 4 | Walt Disney Studios Motion Pictures | - |
| 3 | 3 | - | Hot Tub Time Machine | $13,650,000 | $14,020,502 | +$370,502 | +2.7% | 2,754 | $13,650,000 | $14,020,502 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 4 | 4 | - | The Bounty Hunter | $12,400,000 | $12,006,731 | -$393,269 | -3.2% | 3,074 | $38,812,000 | $38,418,433 | 2 | Sony Pictures Releasing | - |
| 5 | 5 | - | Diary of a Wimpy Kid | $10,000,000 | $10,121,961 | +$121,961 | +1.2% | 3,083 | $35,776,000 | $35,898,390 | 2 | Twentieth Century Fox | - |
| 6 | 6 | - | She's Out of My League | $3,526,000 | $3,512,218 | -$13,782 | -0.4% | 2,432 | $25,601,000 | $25,586,560 | 3 | Paramount Pictures | - |
| 7 | 7 | - | Green Zone | $3,350,000 | $3,384,480 | +$34,480 | +1% | 2,564 | $30,440,000 | $30,475,005 | 3 | Universal Pictures | - |
| 8 | 8 | - | Shutter Island | $3,175,000 | $3,187,487 | +$12,487 | +0.4% | 2,123 | $120,600,000 | $120,612,552 | 6 | Paramount Pictures | - |
| 9 | 9 | - | Repo Men | $3,048,000 | $3,010,515 | -$37,485 | -1.2% | 2,519 | $11,342,000 | $11,304,730 | 2 | Universal Pictures | - |
| 10 | 10 | - | Our Family Wedding | $2,200,000 | $2,352,539 | +$152,539 | +6.9% | 1,132 | $16,785,000 | $16,938,462 | 3 | Fox Searchlight Pictures | - |
| 11 | 11 | - | Avatar | $2,015,000 | $2,047,475 | +$32,475 | +1.6% | 930 | $740,408,000 | $740,440,529 | 15 | Twentieth Century Fox | - |
| 12 | 12 | - | Remember Me | $1,900,000 | $1,935,640 | +$35,640 | +1.9% | 1,935 | $17,001,000 | $17,036,782 | 3 | Summit Entertainment | - |
| 13 | 13 | - | The Ghost Writer | $1,650,000 | $1,696,784 | +$46,784 | +2.8% | 819 | $9,192,000 | $9,239,079 | 6 | Summit Entertainment | - |
| 14 | 14 | - | Greenberg | $1,058,000 | $1,021,151 | -$36,849 | -3.5% | 181 | $1,237,000 | $1,200,139 | 2 | Focus Features | - |
| 15 | 15 | - | Chloe | $1,002,000 | $900,688 | -$101,312 | -10.1% | 350 | $1,002,000 | $900,688 | 1 | Sony Pictures Classics | - |
| 16 | 16 | - | Crazy Heart | $800,000 | $791,256 | -$8,744 | -1.1% | 849 | $37,754,000 | $37,746,228 | 15 | Fox Searchlight Pictures | - |
| 17 | 17 | - | Brooklyn's Finest | $774,000 | $766,098 | -$7,902 | -1% | 739 | $26,236,000 | $26,228,372 | 4 | Overture Films | - |
| 18 | 18 | - | The Crazies | $708,000 | $724,623 | +$16,623 | +2.3% | 851 | $37,657,000 | $37,673,626 | 5 | Overture Films | - |
| 19 | 19 | - | Percy Jackson & the Olympians: The Lightning Thief | $670,000 | $672,691 | +$2,691 | +0.4% | 790 | $86,103,000 | $86,106,485 | 7 | Twentieth Century Fox | - |
| 20 | 22 | +2 | The Runaways | $445,000 | $455,107 | +$10,107 | +2.3% | 237 | $1,571,000 | $1,580,559 | 2 | Apparition | - |
| 21 | 23 | +2 | Hubble | $375,000 | $382,162 | +$7,162 | +1.9% | 39 | - | $1,070,443 | 2 | Warner Bros. | - |
| 22 | 24 | +2 | The Girl with the Dragon Tattoo | $352,000 | $341,470 | -$10,530 | -3% | 44 | $840,000 | $829,740 | 2 | Music Box Films | - |
| 23 | 39 | +16 | Up in the Air | $277,000 | $53,573 | -$223,427 | -80.7% | 87 | $83,770,000 | $83,775,048 | 17 | Paramount Pictures | - |
| 24 | 26 | +2 | Alvin and the Chipmunks: The Squeakquel | $260,000 | $275,949 | +$15,949 | +6.1% | 297 | $219,012,000 | $219,028,490 | 14 | Twentieth Century Fox | - |
| 25 | 28 | +3 | The Last Station | $195,000 | $176,651 | -$18,349 | -9.4% | 165 | $6,043,000 | $6,024,497 | 11 | Sony Pictures Classics | - |
| 26 | 30 | +4 | A Prophet | $149,000 | $145,004 | -$3,996 | -2.7% | 83 | $1,331,000 | $1,326,760 | 5 | Sony Pictures Classics | - |
| 27 | 32 | +5 | The Wolfman | $93,000 | $98,615 | +$5,615 | +6% | 164 | $61,932,000 | $61,937,495 | 7 | Universal Pictures | - |
| 28 | 36 | +8 | It's Complicated | $82,000 | $74,750 | -$7,250 | -8.8% | 115 | $112,710,000 | $112,703,470 | 14 | Universal Pictures | - |
| 29 | 41 | +12 | City Island | $49,000 | $48,077 | -$923 | -1.9% | 7 | $92,600 | $91,749 | 2 | Anchor Bay Films | - |
| 30 | 44 | +14 | A Single Man | $46,000 | $42,944 | -$3,056 | -6.6% | 54 | $9,049,000 | $9,045,467 | 16 | The Weinstein Company | - |
| 31 | 47 | +16 | The White Ribbon | $37,400 | $35,349 | -$2,051 | -5.5% | 50 | $2,025,600 | $2,023,523 | 13 | Sony Pictures Classics | - |
| 32 | 50 | +18 | An Education | $35,700 | $30,865 | -$4,835 | -13.5% | 49 | $12,516,900 | $12,512,069 | 25 | Sony Pictures Classics | - |
| 33 | 49 | +16 | Waking Sleeping Beauty | $33,100 | $33,115 | +$15 | <0.1% | 5 | $33,100 | $33,115 | 1 | Walt Disney Studios Motion Pictures | - |
| 34 | 58 | +24 | The Secret of Kells | $15,900 | $16,782 | +$882 | +5.5% | 7 | $117,400 | $118,192 | 4 | GKIDS | - |
| 35 | 65 | +30 | Lbs. | $10,900 | $11,690 | +$790 | +7.2% | 1 | $10,900 | $11,690 | 1 | Truly Indie | - |
| 36 | 89 | +53 | The Messenger | $4,200 | $4,309 | +$109 | +2.6% | 10 | $1,068,200 | $1,068,286 | 20 | Oscilloscope | - |
| 37 | 91 | +54 | Terribly Happy | $3,800 | $4,002 | +$202 | +5.3% | 4 | $104,400 | $104,612 | 8 | Oscilloscope | - |
| 38 | 95 | +57 | The Exploding Girl | $2,200 | $2,414 | +$214 | +9.7% | 2 | $13,100 | $13,225 | 3 | Oscilloscope | - |
| 39 | 97 | +58 | Preacher's Kid | $1,900 | $2,034 | +$134 | +7.1% | 6 | $506,900 | $507,085 | 9 | 8x Entertainment | - |
