| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | How to Train Your Dragon | $3,664,530 | - | 367 | - | $9,985 | $3,664,530 | 1 | Paramount Pictures International | true | false |
| 2 | 1 | Alice in Wonderland | $2,915,119 | -19.1% | 393 | -51 | $7,417 | $27,448,326 | 4 | Walt Disney Pictures | false | false |
| 3 | 2 | The Bounty Hunter | $1,368,685 | +8.2% | 204 | - | $6,709 | $3,037,708 | 2 | Sony Pictures Releasing | false | false |
| 4 | 4 | The Blind Side | $1,082,827 | +16.8% | 219 | -7 | $4,944 | $9,888,166 | 5 | Roadshow Films | false | false |
| 5 | 3 | Green Zone | $1,064,836 | -6.1% | 243 | -2 | $4,382 | $4,909,929 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | - | The Girl with the Dragon Tattoo | $698,155 | - | 53 | - | $13,172 | $928,141 | 1 | Rialto Distribution | true | false |
| 7 | - | Nanny McPhee Returns | $606,960 | - | 123 | - | $4,934 | $606,960 | - | Universal Pictures International (UPI) | - | false |
| 8 | 5 | Cop Out | $537,039 | -7.6% | 145 | -1 | $3,703 | $1,314,295 | 2 | Warner Bros. | false | false |
| 9 | 6 | The Hurt Locker | $518,958 | -1.7% | 76 | +2 | $6,828 | $4,165,710 | 6 | Roadshow Films | false | false |
| 10 | 7 | Avatar | $440,669 | -14.4% | 93 | -46 | $4,738 | $101,350,195 | 15 | 20th Century Fox International | false | false |
| 11 | 8 | Dear John | $368,971 | -6.3% | 150 | -44 | $2,459 | $4,014,820 | 4 | Roadshow Films | false | false |
| 12 | 9 | The Rebound | $338,528 | -11.2% | 190 | +1 | $1,781 | $882,937 | 2 | Roadshow Films | false | false |
| 13 | 10 | Shutter Island | $301,055 | -2.4% | 109 | -45 | $2,761 | $8,975,063 | 6 | Paramount Pictures International | false | false |
| 14 | 11 | Remember Me | $215,914 | -13.3% | 138 | -36 | $1,564 | $1,216,554 | 3 | Hoyts Distribution | false | false |
| 15 | - | The Spy Next Door 2010 Re-release | $213,400 | - | 34 | - | $6,276 | $216,097 | 1 | Roadshow Films | true | false |
| 16 | 13 | The Men Who Stare at Goats | $143,437 | -7.1% | 47 | -11 | $3,051 | $1,326,574 | 4 | Sony Pictures Releasing | false | false |
| 17 | 14 | A Single Man | $130,093 | +14.2% | 28 | - | $4,646 | $1,156,502 | 5 | Icon Film Distribution Australia | false | false |
| 18 | 15 | Brothers | $97,861 | +14.9% | 22 | - | $4,448 | $218,142 | 2 | Roadshow Films | false | false |
| 19 | 18 | Precious | $66,808 | +78.1% | 41 | +2 | $1,629 | $1,223,232 | 8 | Icon Film Distribution Australia | false | false |
| 20 | - | The Last Station 2010 Re-release | $63,267 | - | 26 | - | $2,433 | $63,267 | - | Becker Film Group | - | false |
| 21 | - | Going Vertical: The Shortboard Revolution | $3,617 | - | 14 | - | $258 | $3,617 | 1 | N/A | true | false |
| 22 | - | Little Ashes | $3,166 | - | 3 | - | $1,055 | $3,166 | 1 | Kojo Pictures | true | false |
| 23 | - | Lad Gaya Pecha | $2,719 | - | 3 | - | $906 | $2,719 | 1 | Eros Worldwide | true | false |
