| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $676,786 | - | 18 | - | $37,599 | $868,643 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Shutter Island | $134,545 | -41.7% | 16 | - | $8,409 | $606,623 | 2 | United International Pictures | false | false |
| 3 | - | Up in the Air | $80,127 | - | 16 | - | $5,007 | $94,650 | 1 | United International Pictures | true | false |
| 4 | - | Nodame Cantabile: The Movie II | $62,430 | - | 11 | - | $5,675 | $78,244 | 1 | N/A | true | false |
| 5 | 3 | The Blind Side | $60,872 | -25.8% | 13 | - | $4,682 | $235,674 | 2 | Warner Bros. | false | false |
| 6 | 2 | Avatar | $36,438 | -61.4% | 9 | -5 | $4,048 | $13,394,440 | 12 | 20th Century Fox International | false | false |
| 7 | 5 | Nine | $32,295 | -57.5% | 13 | - | $2,484 | $192,299 | 2 | N/A | false | false |
| 8 | 4 | Monga | $25,507 | -66.6% | 16 | -3 | $1,594 | $3,624,391 | 5 | Warner Bros. | false | false |
| 9 | 6 | Percy Jackson & the Olympians: The Lightning Thief | $19,343 | -68.9% | 13 | -3 | $1,487 | $1,169,882 | 4 | 20th Century Fox International | false | false |
| 10 | 7 | True Legend | $10,962 | -76.8% | 12 | -3 | $913 | $98,665 | 2 | N/A | false | false |
| 11 | - | A Single Man | $8,993 | - | 7 | - | $1,284 | $11,763 | 1 | N/A | true | false |
| 12 | 8 | Valentine's Day | $4,170 | -81.3% | 4 | -11 | $1,042 | $557,945 | 4 | Warner Bros. | false | false |
| 13 | 10 | The Road | $3,610 | -76.8% | 5 | -4 | $722 | $32,726 | 2 | N/A | false | false |
| 14 | 12 | Hot Summer Days | $1,475 | -86.5% | 9 | -2 | $163 | $23,828 | 2 | N/A | false | false |
| 15 | 14 | From Paris with Love | $1,472 | -79.4% | 1 | -5 | $1,472 | $419,464 | 5 | N/A | false | false |
| 16 | 9 | Little Big Soldier | $1,156 | -93.7% | 2 | -10 | $578 | $29,515 | 2 | N/A | false | false |
| 17 | 17 | 14 Blades | $1,045 | -72.6% | 1 | -3 | $1,045 | $501,231 | 5 | Long Shong Entertainment Multimedia Company | false | false |
| 18 | 11 | I Love You Phillip Morris | $900 | -92% | 1 | -8 | $900 | $352,740 | 4 | N/A | false | false |
| 19 | 15 | The Book of Eli | $454 | -93.6% | 3 | -13 | $151 | $519,389 | 4 | Sony Pictures Releasing | false | false |
| 20 | 18 | Villon's Wife | $32 | -99.1% | 1 | -1 | $32 | $19,685 | 4 | N/A | false | false |
