| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | Avatar | $945,022 | +9.6% | 259 | -6 | $3,648 | $53,523,483 | 12 | 20th Century Fox International | false | false |
| 2 | 1 | Percy Jackson & the Olympians: The Lightning Thief | $791,550 | -16% | 278 | +1 | $2,847 | $6,650,579 | 4 | 20th Century Fox International | false | false |
| 3 | 2 | It's Complicated | $737,208 | -16.6% | 171 | -7 | $4,311 | $2,059,945 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | - | Toy Story 2 2009 Re-release | $520,576 | - | 107 | - | $4,865 | $520,576 | 1 | Walt Disney Pictures | true | false |
| 5 | 4 | Valentine's Day | $520,128 | -21.6% | 157 | -1 | $3,312 | $2,889,939 | 3 | Warner Bros. | false | false |
| 6 | - | Love Happens | $404,530 | - | 129 | - | $3,135 | $404,530 | 1 | PlayArte Pictures | true | false |
| 7 | 6 | The Wolfman | $281,935 | -31.3% | 222 | -34 | $1,269 | $3,619,344 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 8 | Alvin and the Chipmunks: The Squeakquel | $170,786 | -19.9% | 254 | -36 | $672 | $21,098,759 | 9 | 20th Century Fox International | false | false |
| 9 | 7 | The Lovely Bones | $161,383 | -54.4% | 166 | -6 | $972 | $1,420,126 | 3 | Paramount Pictures International | false | false |
| 10 | - | Brothers | $156,003 | - | 61 | - | $2,557 | $156,003 | 1 | N/A | true | false |
| 11 | 9 | The Final Destination | $127,521 | -24% | 131 | -19 | $973 | $4,243,211 | 5 | PlayArte Pictures | false | false |
| 12 | - | Carriers | $121,888 | - | 56 | - | $2,176 | $121,888 | 1 | PlayArte Pictures | true | false |
| 13 | 10 | Tooth Fairy | $111,539 | -17% | 166 | +12 | $671 | $4,723,262 | 7 | 20th Century Fox International | false | false |
| 14 | 12 | Invictus | $90,403 | -18.5% | 73 | -1 | $1,238 | $1,757,987 | 6 | Warner Bros. | false | false |
| 15 | 11 | Up in the Air | $89,938 | -26% | 103 | -30 | $873 | $4,323,723 | 7 | Paramount Pictures International | false | false |
| 16 | - | A Single Man | $87,521 | - | 29 | - | $3,017 | $87,521 | 1 | Paris Filmes | true | false |
| 17 | 15 | Precious | $69,663 | -5.4% | 64 | -7 | $1,088 | $679,934 | 4 | PlayArte Pictures | false | false |
| 18 | - | Crazy Heart | $65,866 | - | 15 | - | $4,391 | $65,866 | 1 | 20th Century Fox International | true | false |
| 19 | 16 | High School Musical: O Desafio | $39,308 | -26.4% | 97 | -48 | $405 | $968,517 | 5 | Walt Disney Pictures | false | false |
| 20 | 17 | Edge of Darkness | $36,415 | -24.5% | 71 | -19 | $512 | $2,228,898 | 6 | N/A | false | false |
| 21 | 19 | Xuxa and the Mystery of the Little Ugly Princess | $34,515 | -16.6% | 113 | -5 | $305 | $4,491,642 | 11 | PlayArte Pictures | false | false |
| 22 | 18 | An Education | $33,809 | -28.4% | 10 | -3 | $3,380 | $210,162 | 3 | Sony Pictures Releasing | false | false |
| 23 | 13 | Sherlock Holmes | $32,631 | -65.1% | 39 | -51 | $836 | $12,163,758 | 9 | Warner Bros. | false | false |
| 24 | 20 | Zombieland | $27,280 | -29.5% | 38 | +6 | $717 | $364,594 | 6 | Sony Pictures Releasing | false | false |
| 25 | 14 | Pandorum | $24,922 | -67.3% | 28 | -8 | $890 | $133,538 | 2 | N/A | false | false |
| 26 | 24 | The Hurt Locker | $23,196 | +39.9% | 23 | +5 | $1,008 | $367,382 | 5 | N/A | false | false |
| 27 | 21 | The White Ribbon | $21,145 | -32.5% | 19 | -4 | $1,112 | $321,315 | 4 | N/A | false | false |
| 28 | 22 | Nine | $12,820 | -39.9% | 29 | -2 | $442 | $482,212 | 6 | Sony Pictures Releasing | false | false |
| 29 | 23 | The Messenger | $5,379 | -69.4% | 10 | -7 | $537 | $95,961 | 3 | Paris Filmes | false | false |
| 30 | 28 | Julie & Julia | $4,053 | -33.7% | 14 | -5 | $289 | $1,248,726 | 15 | Sony Pictures Releasing | false | false |
| 31 | 32 | Easy Virtue | $1,708 | -12.3% | 5 | +1 | $341 | $180,777 | 20 | Sony Pictures Releasing | false | false |
| 32 | 30 | The Princess and the Frog | $1,092 | -54.9% | 11 | -2 | $99 | $3,907,365 | 13 | Walt Disney Pictures | false | false |
| 33 | 33 | A Christmas Carol | $491 | +60.5% | 3 | +1 | $163 | $3,006,529 | 18 | Walt Disney Pictures | false | false |
| 34 | 34 | 2012 | $339 | +303.6% | 1 | - | $339 | $25,652,732 | 17 | Sony Pictures Releasing | false | false |
