| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $198,093 | - | 12 | - | $16,507 | $199,097 | 1 | Walt Disney Pictures | true | false |
| 2 | 3 | The Wolfman | $11,391 | -37.3% | 8 | -3 | $1,423 | $124,209 | 4 | Universal Pictures International (UPI) | false | false |
| 3 | 4 | Edge of Darkness | $10,110 | -29.5% | 7 | - | $1,444 | $28,382 | 2 | Warner Bros. | false | false |
| 4 | 2 | Percy Jackson & the Olympians: The Lightning Thief | $9,145 | -51.4% | 8 | -3 | $1,143 | $98,806 | 4 | 20th Century Fox International | false | false |
| 5 | 1 | Avatar | $8,887 | -63.9% | 10 | - | $888 | $1,439,397 | 12 | 20th Century Fox International | false | false |
| 6 | - | Up in the Air | $8,181 | - | 8 | - | $1,022 | $8,181 | 1 | Paramount Pictures International | true | false |
| 7 | 8 | The Hurt Locker | $7,558 | +6.6% | 2 | - | $3,779 | $26,435 | 3 | - | false | false |
| 8 | 6 | Old Dogs | $5,677 | -48.2% | 5 | +1 | $1,135 | $124,391 | 6 | Walt Disney Pictures | false | false |
| 9 | 7 | All About Steve | $4,697 | -42.6% | 4 | - | $1,174 | $15,265 | 2 | 20th Century Fox International | false | false |
| 10 | 12 | Tooth Fairy | $4,140 | -13.1% | 5 | +1 | $828 | $171,312 | 8 | 20th Century Fox International | false | false |
| 11 | 11 | Couples Retreat | $2,701 | -48.3% | 4 | - | $675 | $9,736 | 2 | Universal Pictures International (UPI) | false | false |
| 12 | 9 | Sorority Row | $2,614 | -62.8% | 5 | -1 | $522 | $12,324 | 2 | - | false | false |
| 13 | 10 | Valentine's Day | $1,798 | -67.7% | 3 | -1 | $599 | $44,711 | 4 | Warner Bros. | false | false |
| 14 | 14 | Invictus | $1,702 | -21.6% | 2 | - | $851 | $32,523 | 5 | Warner Bros. | false | false |
| 15 | 18 | Sherlock Holmes | $499 | -47.6% | 1 | - | $499 | $133,079 | 8 | Warner Bros. | false | false |
