| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $40,570 | -16.6% | 14 | - | $2,897 | $1,236,179 | 11 | 20th Century Fox International | false | false |
| 2 | - | The Wolfman | $18,660 | - | 6 | - | $3,110 | $21,798 | 1 | United International Pictures | true | false |
| 3 | - | Percy Jackson & the Olympians: The Lightning Thief | $11,029 | - | 7 | - | $1,575 | $12,004 | 1 | 20th Century Fox International | true | false |
| 4 | 2 | Valentine's Day | $9,851 | -51.4% | 6 | - | $1,641 | $105,935 | 3 | Warner Bros. | false | false |
| 5 | 4 | Toy Story 2009 Re-release | $6,451 | -20.7% | 3 | - | $2,150 | $23,820 | 3 | Walt Disney Pictures | false | false |
| 6 | 6 | The Princess and the Frog | $5,290 | -15.8% | 6 | - | $881 | $58,124 | 5 | Walt Disney Pictures | false | false |
| 7 | 3 | The Lovely Bones | $3,938 | -65.6% | 5 | - | $787 | $18,192 | 2 | United International Pictures | false | false |
| 8 | 8 | Sherlock Holmes | $3,902 | -16.8% | 6 | - | $650 | $222,435 | 8 | Warner Bros. | false | false |
| 9 | - | The Imaginarium of Doctor Parnassus | $3,328 | - | 2 | - | $1,664 | $25,523 | 3 | N/A | false | false |
| 10 | 5 | Law Abiding Citizen | $2,933 | -61.8% | 5 | - | $586 | $17,328 | 2 | N/A | false | false |
| 11 | 9 | Alvin and the Chipmunks: The Squeakquel | $2,816 | -25.8% | 6 | - | $469 | $54,336 | 7 | 20th Century Fox International | false | false |
| 12 | 13 | Arthur and the Revenge of Maltazard | $2,545 | -0.5% | 6 | - | $424 | $60,371 | 9 | N/A | false | false |
| 13 | 10 | Did You Hear About the Morgans? | $1,783 | -39.1% | 5 | -2 | $356 | $83,607 | 6 | Sony Pictures Releasing | false | false |
| 14 | 7 | Up in the Air | $1,658 | -71.5% | 5 | - | $331 | $44,849 | 4 | United International Pictures | false | false |
| 15 | 11 | Nine | $1,511 | -48.1% | 4 | - | $377 | $27,538 | 4 | N/A | false | false |
| 16 | - | Don't Look Back | $1,051 | - | 2 | - | $525 | $1,108 | 1 | N/A | true | false |
| 17 | 12 | Old Dogs | $990 | -63.5% | 5 | - | $198 | $75,698 | 7 | Walt Disney Pictures | false | false |
| 18 | 15 | Garfield's Fun Fest | $911 | +9.9% | 2 | - | $455 | $13,579 | 10 | N/A | false | false |
| 19 | 17 | The White Ribbon | $321 | -8.3% | 1 | - | $321 | $11,912 | 2 | N/A | false | false |
| 20 | 16 | The Twilight Saga: New Moon | $254 | -62% | 5 | - | $50 | $111,027 | 13 | N/A | false | false |
| 21 | 14 | It's Complicated | $138 | -86.4% | 9 | - | $15 | $118,233 | 10 | United International Pictures | false | false |
| 22 | 26 | Paranormal Activity | $120 | +87.5% | 5 | - | $24 | $58,613 | 14 | N/A | false | false |
| 23 | 19 | The Flight Before Christmas | $116 | -57.7% | 3 | - | $38 | $12,883 | 12 | N/A | false | false |
| 24 | 28 | North Face | $95 | +427.8% | 2 | - | $47 | $2,013 | 11 | N/A | false | false |
| 25 | 27 | Planet 51 | $88 | +193.3% | 7 | - | $12 | $38,221 | 13 | N/A | false | false |
| 26 | 23 | The Box | $85 | -22.7% | 2 | - | $42 | $10,068 | 7 | N/A | false | false |
| 27 | 20 | Broken Embraces | $48 | -72.3% | 5 | - | $9 | $37,972 | 17 | N/A | false | false |
