| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | When in Rome | $232,729 | - | 61 | - | $3,815 | $232,729 | 1 | Walt Disney Pictures | true | false |
| 2 | 2 | Avatar | $154,010 | +7.7% | 36 | -5 | $4,278 | $7,285,905 | 11 | 20th Century Fox International | false | false |
| 3 | 1 | The Wolfman | $122,666 | -54.1% | 86 | - | $1,426 | $467,129 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | - | The Lovely Bones | $58,858 | - | 42 | - | $1,401 | $58,858 | 1 | Paramount Pictures International | true | false |
| 5 | 5 | Shutter Island | $58,093 | -26.9% | 20 | - | $2,904 | $166,442 | 2 | N/A | false | false |
| 6 | 4 | Percy Jackson & the Olympians: The Lightning Thief | $37,648 | -62% | 61 | -1 | $617 | $425,312 | 3 | 20th Century Fox International | false | false |
| 7 | - | Dear John | $29,510 | - | 13 | - | $2,270 | $29,510 | 1 | N/A | true | false |
| 8 | 6 | Did You Hear About the Morgans? | $26,167 | -62% | 28 | -2 | $934 | $261,993 | 3 | Sony Pictures Releasing | false | false |
| 9 | 3 | Valentine's Day | $21,748 | -79.2% | 57 | -2 | $381 | $578,600 | 3 | Warner Bros. | false | false |
| 10 | 8 | The Spy Next Door 2010 Re-release | $13,984 | -47.5% | 12 | - | $1,165 | $45,877 | 2 | N/A | false | false |
| 11 | 7 | Kandagar | $9,358 | -64.9% | 56 | +3 | $167 | $406,679 | 4 | N/A | false | false |
| 12 | 12 | A Christmas Carol | $8,614 | +49.7% | 2 | - | $4,307 | $1,322,083 | 9 | Walt Disney Pictures | false | false |
| 13 | 9 | Leap Year | $8,104 | -56.4% | 36 | -14 | $225 | $323,630 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | - | Dorian Gray | $6,125 | - | 20 | - | $306 | $144,125 | 4 | N/A | false | false |
| 15 | 10 | Nasha Russia. Yaytsa sudby | $4,500 | -70% | 50 | -20 | $90 | $1,466,269 | 6 | N/A | false | false |
| 16 | 11 | The Imaginarium of Doctor Parnassus | $3,544 | -65.2% | 16 | -4 | $221 | $139,689 | 4 | N/A | false | false |
| 17 | - | From Paris with Love | $3,029 | - | 4 | - | $757 | $82,610 | 4 | N/A | false | false |
| 18 | 16 | The Princess and the Frog | $2,786 | +6.7% | 6 | - | $464 | $654,815 | 8 | Walt Disney Pictures | false | false |
| 19 | 15 | Sherlock Holmes | $1,809 | -38.8% | 4 | -2 | $452 | $1,207,224 | 7 | Warner Bros. | false | false |
| 20 | 13 | It's Complicated | $1,456 | -65.1% | 10 | -8 | $145 | $439,653 | 6 | Universal Pictures International (UPI) | false | false |
| 21 | 14 | Up in the Air | $1,172 | -68.6% | 19 | -6 | $61 | $245,062 | 5 | Paramount Pictures International | false | false |
| 22 | 19 | Alvin and the Chipmunks: The Squeakquel | $1,000 | -2.4% | 2 | - | $500 | $381,668 | 10 | 20th Century Fox International | false | false |
| 23 | 17 | Toy Story 2 2009 Re-release | $823 | -47% | 1 | - | $823 | $30,855 | 6 | Walt Disney Pictures | false | false |
| 24 | 20 | Solomon Kane | $412 | +35.1% | 4 | -1 | $103 | $108,132 | 7 | N/A | false | false |
| 25 | 18 | Katyn | $240 | -79% | 5 | -5 | $48 | $1,686 | 2 | N/A | false | false |
