| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $265,517 | -18.1% | 64 | -3 | $4,148 | $12,734,968 | 11 | 20th Century Fox International | false | false |
| 2 | - | Toy Story 2 2009 Re-release | $182,288 | - | 36 | - | $5,063 | $182,288 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | The Wolfman | $153,894 | -23.3% | 90 | -2 | $1,709 | $775,952 | 3 | United International Pictures | false | false |
| 4 | 3 | Percy Jackson & the Olympians: The Lightning Thief | $128,808 | -16.1% | 82 | -2 | $1,570 | $608,234 | 3 | 20th Century Fox International | false | false |
| 5 | - | Law Abiding Citizen | $92,429 | - | 54 | - | $1,711 | $92,429 | 1 | Cineplex | true | false |
| 6 | 6 | Tooth Fairy | $73,848 | +1.1% | 52 | +2 | $1,420 | $959,408 | 6 | 20th Century Fox International | false | false |
| 7 | - | Couples Retreat | $56,366 | - | 26 | - | $2,167 | $56,366 | 1 | United International Pictures | true | false |
| 8 | 7 | Precious | $55,424 | -1.2% | 19 | -1 | $2,917 | $137,541 | 2 | Cine Colombia | false | false |
| 9 | 5 | Valentine's Day | $53,857 | -33.2% | 32 | -10 | $1,683 | $300,870 | 3 | Warner Bros. | false | false |
| 10 | 10 | Old Dogs | $32,812 | -16.7% | 45 | - | $729 | $1,089,573 | 8 | Walt Disney Pictures | false | false |
| 11 | 9 | Invictus | $29,740 | -26.1% | 26 | - | $1,143 | $293,862 | 4 | Warner Bros. | false | false |
| 12 | 8 | Cirque du Freak: The Vampire's Assistant | $26,540 | -42.4% | 35 | -3 | $758 | $86,008 | 2 | United International Pictures | false | false |
| 13 | 11 | The Lovely Bones | $20,502 | -43.6% | 25 | -1 | $820 | $70,503 | 2 | United International Pictures | false | false |
| 14 | 12 | The Hurt Locker | $13,635 | -28.6% | 11 | - | $1,239 | $84,340 | 3 | Cineplex | false | false |
| 15 | 14 | An Education | $9,244 | -28.2% | 6 | - | $1,540 | $27,757 | 2 | Sony Pictures Releasing | false | false |
| 16 | - | Fame | $8,533 | - | 15 | - | $568 | $8,533 | 1 | Cine Colombia | true | false |
| 17 | 15 | Alvin and the Chipmunks: The Squeakquel | $7,710 | -10.1% | 31 | -1 | $248 | $1,355,272 | 9 | 20th Century Fox International | false | false |
| 18 | 20 | Broken Embraces | $6,567 | +114.5% | 11 | +3 | $597 | $90,409 | 4 | United International Pictures | false | false |
| 19 | 13 | Up in the Air | $6,526 | -54.8% | 12 | -5 | $543 | $236,937 | 6 | United International Pictures | false | false |
| 20 | 17 | Nine | $4,093 | -22.2% | 6 | -2 | $682 | $120,957 | 5 | Sony Pictures Releasing | false | false |
| 21 | - | The Soloist | $4,056 | - | 5 | - | $811 | $57,848 | 7 | United International Pictures | false | false |
| 22 | 18 | The Princess and the Frog | $3,994 | -23.6% | 19 | -6 | $210 | $1,817,410 | 10 | Walt Disney Pictures | false | false |
| 23 | 23 | Astro Boy | $3,073 | +90.4% | 7 | -2 | $439 | $74,109 | 7 | Cine Colombia | false | false |
| 24 | 4 | Toy Story 2009 Re-release | $2,851 | -98% | 1 | -36 | $2,851 | $162,111 | 2 | Walt Disney Pictures | false | false |
| 25 | 24 | Departures | $2,661 | +172.4% | 4 | +1 | $665 | $106,210 | 7 | Cine Colombia | false | false |
| 26 | 19 | Ninja Assassin | $2,145 | -54.4% | 5 | -3 | $429 | $131,306 | 5 | Warner Bros. | false | false |
| 27 | 16 | Sherlock Holmes | $2,065 | -65.6% | 2 | -6 | $1,032 | $1,657,788 | 8 | Warner Bros. | false | false |
| 28 | 22 | Zombieland | $1,615 | -6.2% | 1 | -3 | $1,615 | $163,039 | 7 | Sony Pictures Releasing | false | false |
| 29 | 21 | The Stepfather | $1,314 | -52.8% | 2 | -1 | $657 | $96,156 | 12 | Sony Pictures Releasing | false | false |
