| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $46,238 | +14.6% | 7 | -2 | $6,605 | $1,001,897 | 10 | 20th Century Fox International | false | false |
| 2 | 2 | Valentine's Day | $20,634 | -38.8% | 7 | - | $2,947 | $103,231 | 2 | Warner Bros. | false | false |
| 3 | - | Toy Story 2 2009 Re-release | $17,795 | - | 6 | - | $2,965 | $17,795 | 1 | Walt Disney Pictures | true | false |
| 4 | - | An Education | $17,218 | - | 4 | - | $4,304 | $17,218 | 1 | Sony Pictures Releasing | true | false |
| 5 | 4 | Invictus | $14,312 | -1.9% | 7 | -1 | $2,044 | $179,401 | 5 | Warner Bros. | false | false |
| 6 | 8 | Old Dogs | $11,825 | +58.8% | 4 | -1 | $2,956 | $125,153 | 5 | Walt Disney Pictures | false | false |
| 7 | 5 | Percy Jackson & the Olympians: The Lightning Thief | $10,785 | +12% | 5 | - | $2,157 | $34,209 | 2 | 20th Century Fox International | false | false |
| 8 | 3 | The Wolfman | $10,564 | -31.3% | 5 | - | $2,112 | $38,123 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 6 | Precious | $7,877 | -12% | 4 | - | $1,969 | $25,585 | 2 | N/A | false | false |
| 10 | 10 | Sherlock Holmes | $6,502 | -1% | 4 | -1 | $1,625 | $192,409 | 6 | Warner Bros. | false | false |
| 11 | 11 | It's Complicated | $5,980 | +4.3% | 5 | - | $1,196 | $166,098 | 6 | United International Pictures | false | false |
| 12 | 14 | Alvin and the Chipmunks: The Squeakquel | $5,855 | +73.9% | 4 | - | $1,463 | $159,489 | 8 | 20th Century Fox International | false | false |
| 13 | 9 | The Hurt Locker | $4,728 | -29.5% | 4 | - | $1,182 | $38,882 | 3 | N/A | false | false |
| 14 | 13 | The Girl with the Dragon Tattoo | $4,564 | +25.6% | 3 | -1 | $1,521 | $69,177 | 5 | N/A | false | false |
| 15 | 12 | Up in the Air | $4,371 | +5.5% | 5 | - | $874 | $128,552 | 5 | Paramount Pictures International | false | false |
| 16 | 17 | Easy Virtue | $2,119 | +28.7% | 4 | +2 | $529 | $28,007 | 4 | Sony Pictures Releasing | false | false |
| 17 | 15 | Paris 36 | $2,025 | -22% | 2 | - | $1,012 | $6,651 | 2 | N/A | false | false |
| 18 | 18 | The Princess and the Frog | $1,923 | +16.9% | 2 | -2 | $961 | $79,009 | 7 | Walt Disney Pictures | false | false |
| 19 | 16 | Astro Boy | $1,030 | -46.8% | 4 | - | $257 | $29,356 | 4 | N/A | false | false |
| 20 | 21 | Paranormal Activity | $891 | +39.7% | 1 | - | $891 | $58,368 | 8 | N/A | false | false |
| 21 | 20 | The Young Victoria | $436 | -32.8% | 1 | - | $436 | $40,665 | 6 | N/A | false | false |
