| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Valentine's Day | $68,786 | - | 9 | - | $7,642 | $110,777 | 1 | Warner Bros. | true | false |
| 2 | 2 | Alvin and the Chipmunks: The Squeakquel | $57,440 | +36.7% | 13 | - | $4,418 | $456,462 | 4 | 20th Century Fox International | false | false |
| 3 | 1 | Avatar | $47,301 | -6.6% | 18 | - | $2,627 | $1,740,951 | 10 | 20th Century Fox International | false | false |
| 4 | - | The Wolfman | $36,439 | - | 7 | - | $5,205 | $45,054 | 1 | United International Pictures | true | false |
| 5 | 3 | Did You Hear About the Morgans? | $16,684 | -34.3% | 8 | - | $2,085 | $98,009 | 3 | Sony Pictures Releasing | false | false |
| 6 | 6 | Cloudy with a Chance of Meatballs | $15,124 | +93.1% | 13 | - | $1,163 | $28,223 | 2 | Sony Pictures Releasing | false | false |
| 7 | 11 | The Princess and the Frog | $11,990 | +137.1% | 9 | - | $1,332 | $96,529 | 5 | Walt Disney Pictures | false | false |
| 8 | 7 | Edge of Darkness | $5,093 | -33.1% | 4 | - | $1,273 | $17,772 | 2 | N/A | false | false |
| 9 | 5 | The Men Who Stare at Goats | $5,085 | -39.4% | 4 | - | $1,271 | $64,253 | 4 | N/A | false | false |
| 10 | 4 | Sherlock Holmes | $4,494 | -47.5% | 9 | - | $499 | $253,217 | 7 | Warner Bros. | false | false |
| 11 | 10 | Up in the Air | $3,692 | -36.3% | 5 | - | $738 | $116,406 | 6 | United International Pictures | false | false |
| 12 | 8 | The Book of Eli | $3,357 | -52.2% | 6 | - | $559 | $85,791 | 5 | N/A | false | false |
| 13 | - | The Hurt Locker | $3,058 | - | 2 | - | $1,529 | $8,343 | 1 | N/A | true | false |
| 14 | - | An Education | $2,187 | - | 2 | - | $1,093 | $3,458 | 1 | N/A | true | false |
| 15 | 12 | Gamer | $1,839 | -42.1% | 6 | - | $306 | $19,952 | 3 | N/A | false | false |
| 16 | 13 | A Serious Man | $1,102 | -41.3% | 1 | - | $1,102 | $7,920 | 3 | N/A | false | false |
