| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $1,357,548 | -9.5% | 142 | -8 | $9,560 | $18,874,602 | 8 | 20th Century Fox International | false | false |
| 2 | - | The Princess and the Frog | $455,099 | - | 137 | - | $3,321 | $631,399 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | Sherlock Holmes | $294,163 | -24.6% | 98 | - | $3,001 | $3,625,154 | 5 | Warner Bros. | false | false |
| 4 | 3 | Edge of Darkness | $256,925 | -20% | 78 | - | $3,293 | $664,843 | 2 | Entertainment One | false | false |
| 5 | 5 | Love Life | $212,033 | -7.7% | 105 | -2 | $2,019 | $12,133,486 | 11 | Benelux Film Distributors | false | false |
| 6 | 6 | Did You Hear About the Morgans? | $185,825 | -17.8% | 47 | - | $3,953 | $975,789 | 3 | Sony Pictures Releasing | false | false |
| 7 | 4 | Alvin and the Chipmunks: The Squeakquel | $174,620 | -28.4% | 113 | -6 | $1,545 | $6,112,535 | 7 | Warner Bros. | false | false |
| 8 | 7 | It's Complicated | $150,333 | -18.8% | 85 | -7 | $1,768 | $3,153,077 | 7 | Universal Pictures International (UPI) | false | false |
| 9 | - | The Spy Next Door 2010 Re-release | $121,768 | - | 44 | - | $2,767 | $123,916 | 1 | A-Film Distribution | true | false |
| 10 | 8 | The Girl Who Played with Fire | $120,349 | -32% | 56 | -2 | $2,149 | $660,032 | 3 | Benelux Film Distributors | false | false |
| 11 | - | The Box | $111,463 | - | 44 | - | $2,533 | $146,043 | 1 | Benelux Film Distributors | true | false |
| 12 | 9 | Up in the Air | $106,314 | -23.2% | 36 | +1 | $2,953 | $992,801 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | - | A Single Man | $92,527 | - | 20 | - | $4,626 | $127,015 | 1 | Cinéart | true | false |
| 14 | - | A Prophet | $82,504 | - | 24 | - | $3,437 | $91,958 | 1 | Cinemien | true | false |
| 15 | - | The Imaginarium of Doctor Parnassus | $81,568 | - | 18 | - | $4,531 | $105,695 | 1 | Entertainment One | true | false |
| 16 | 10 | The Hell of '63 | $79,499 | -23.7% | 65 | -17 | $1,223 | $2,651,361 | 8 | Entertainment One | false | false |
| 17 | 12 | A Serious Man | $72,052 | -25.4% | 22 | +1 | $3,275 | $387,931 | 3 | Universal Pictures International (UPI) | false | false |
| 18 | 11 | Anubis en de wraak van Arghus | $67,351 | -32.5% | 97 | -8 | $694 | $3,569,457 | 8 | Independent Films | false | false |
| 19 | 14 | Where the Wild Things Are | $27,657 | -41.7% | 20 | -4 | $1,382 | $309,012 | 4 | Warner Bros. | false | false |
| 20 | 16 | The Lawyers - A German Story | $23,066 | -8.9% | 17 | - | $1,356 | $797,529 | 12 | Cinéart | false | false |
