| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $85,730 | -12.5% | 9 | - | $9,525 | $1,258,769 | 8 | 20th Century Fox International | false | false |
| 2 | - | Edge of Darkness | $24,573 | - | 3 | - | $8,191 | $24,573 | 1 | N/A | true | false |
| 3 | 2 | Did You Hear About the Morgans? | $22,008 | -26.8% | 6 | - | $3,668 | $61,461 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | The Book of Eli | $21,891 | -23.9% | 6 | - | $3,648 | $115,372 | 3 | Jaguar Film International Distribution | false | false |
| 5 | 4 | It's Complicated | $20,652 | -25.7% | 6 | -1 | $3,442 | $185,631 | 4 | United International Pictures | false | false |
| 6 | 5 | Nine | $13,319 | -18.5% | 6 | - | $2,219 | $109,912 | 4 | Italian International Film | false | false |
| 7 | 6 | Up in the Air | $12,144 | -20.2% | 5 | -1 | $2,428 | $65,911 | 3 | United International Pictures | false | false |
| 8 | 7 | Everybody's Fine | $9,161 | -15.7% | 4 | -1 | $2,290 | $25,243 | 2 | Walt Disney Pictures | false | false |
| 9 | - | New York, I Love You 2010 Re-release | $8,164 | - | 3 | - | $2,721 | $8,164 | 1 | N/A | true | false |
| 10 | 9 | Agora | $5,513 | -23.6% | 4 | -1 | $1,378 | $116,030 | 6 | Italian International Film | false | false |
| 11 | 11 | Law Abiding Citizen | $4,633 | -22.2% | 2 | - | $2,316 | $39,066 | 4 | N/A | false | false |
| 12 | 10 | Paranormal Activity | $3,401 | -51.2% | 4 | - | $850 | $12,504 | 2 | N/A | false | false |
| 13 | - | Ponyo | $3,360 | - | 4 | - | $840 | $3,360 | 1 | N/A | true | false |
| 14 | 14 | Siraj El Wadi | $2,860 | +11.9% | 3 | +1 | $953 | $65,201 | 14 | Italian International Film | false | false |
| 15 | 8 | Sherlock Holmes | $2,146 | -73.6% | 2 | -3 | $1,073 | $304,315 | 7 | Warner Bros. | false | false |
| 16 | 13 | The Princess and the Frog | $2,063 | -36.6% | 4 | - | $515 | $131,851 | 9 | Walt Disney Pictures | false | false |
| 17 | 20 | The Time That Remains | $1,679 | +111.5% | 1 | - | $1,679 | $4,954 | 3 | Prime Pictures | false | false |
| 18 | 15 | Alvin and the Chipmunks: The Squeakquel | $1,629 | -32.8% | 3 | - | $543 | $92,395 | 7 | 20th Century Fox International | false | false |
| 19 | 18 | Old Dogs | $1,579 | +3.5% | 2 | - | $789 | $161,711 | 11 | Walt Disney Pictures | false | false |
| 20 | 17 | Escaping Tel Aviv | $1,398 | -25.1% | 1 | - | $1,398 | $38,125 | 7 | N/A | false | false |
| 21 | - | Sunshine Cleaning | $742 | - | 3 | - | $247 | $742 | 1 | N/A | true | false |
| 22 | 21 | Love Happens | $716 | +0.1% | 2 | -1 | $358 | $83,235 | 12 | Italian International Film | false | false |
| 23 | - | Case 39 | $661 | - | 1 | - | $661 | $84,008 | 9 | United International Pictures | false | false |
| 24 | 16 | To Love a Woman | $602 | -70% | 1 | -1 | $602 | $2,674 | 2 | Italian International Film | false | false |
| 25 | 24 | A Christmas Carol | $592 | +14.1% | 1 | - | $592 | $394,689 | 12 | Walt Disney Pictures | false | false |
| 26 | 26 | The Box | $253 | -17.3% | 1 | - | $253 | $57,651 | 7 | Italian International Film | false | false |
| 27 | 27 | Planet 51 | $239 | +43.1% | 1 | - | $239 | $30,874 | 7 | N/A | false | false |
| 28 | 22 | Little Nicholas | $60 | -91% | 1 | -1 | $60 | $87,312 | 10 | - | false | false |
