| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $517,248 | -11.7% | 104 | -18 | $4,973 | $11,297,775 | 8 | 20th Century Fox International | false | false |
| 2 | 2 | Tooth Fairy | $143,997 | -22% | 53 | - | $2,716 | $662,377 | 3 | 20th Century Fox International | false | false |
| 3 | 4 | Old Dogs | $101,888 | -12.1% | 47 | - | $2,167 | $918,589 | 5 | Walt Disney Pictures | false | false |
| 4 | 3 | Sherlock Holmes | $91,375 | -31.9% | 74 | -12 | $1,234 | $1,590,517 | 5 | Warner Bros. | false | false |
| 5 | - | Invictus | $89,801 | - | 46 | - | $1,952 | $89,801 | 1 | Warner Bros. | true | false |
| 6 | 5 | Alvin and the Chipmunks: The Squeakquel | $37,141 | -34.7% | 78 | -2 | $476 | $1,318,171 | 6 | 20th Century Fox International | false | false |
| 7 | - | Broken Embraces | $36,926 | - | 20 | - | $1,846 | $36,926 | 1 | United International Pictures | true | false |
| 8 | 8 | Up in the Air | $35,130 | -11.7% | 18 | - | $1,951 | $174,736 | 3 | United International Pictures | false | false |
| 9 | 6 | Ninja Assassin | $30,913 | -39.7% | 32 | - | $966 | $105,483 | 2 | Warner Bros. | false | false |
| 10 | 10 | Nine | $26,503 | -18% | 9 | - | $2,944 | $77,889 | 2 | Sony Pictures Releasing | false | false |
| 11 | 9 | The Princess and the Frog | $21,323 | -39.7% | 58 | -18 | $367 | $1,795,491 | 7 | Walt Disney Pictures | false | false |
| 12 | 7 | Paranormal Activity | $19,391 | -51.8% | 25 | +18 | $775 | $1,251,999 | 6 | Cine Colombia | false | false |
| 13 | 13 | Zombieland | $17,698 | +147.6% | 17 | +1 | $1,041 | $148,655 | 4 | Sony Pictures Releasing | false | false |
| 14 | 11 | Departures | $10,270 | -30.5% | 5 | +1 | $2,054 | $84,693 | 4 | Cine Colombia | false | false |
| 15 | 12 | Astro Boy | $6,646 | -19.9% | 22 | -3 | $302 | $66,382 | 4 | Cine Colombia | false | false |
| 16 | 16 | The Stepfather | $4,609 | +266.1% | 6 | +3 | $768 | $88,448 | 9 | Sony Pictures Releasing | false | false |
| 17 | 14 | The Soloist | $1,951 | -68.6% | 3 | -2 | $650 | $52,102 | 4 | United International Pictures | false | false |
| 18 | 15 | Shadows | $828 | -84.1% | 3 | -5 | $276 | $25,636 | 3 | Cine Colombia | false | false |
