| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alvin and the Chipmunks: The Squeakquel | $107,825 | - | 13 | - | $8,294 | $121,552 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Avatar | $79,190 | -24.5% | 18 | - | $4,399 | $1,492,692 | 7 | 20th Century Fox International | false | false |
| 3 | - | The Men Who Stare at Goats | $15,973 | - | 4 | - | $3,993 | $24,054 | 1 | N/A | true | false |
| 4 | 3 | Sherlock Holmes | $14,483 | -45.6% | 9 | - | $1,609 | $215,503 | 4 | Warner Bros. | false | false |
| 5 | 4 | The Book of Eli | $13,263 | -47.6% | 6 | - | $2,210 | $53,618 | 2 | N/A | false | false |
| 6 | 5 | Up in the Air | $12,445 | -42% | 5 | - | $2,489 | $84,989 | 3 | United International Pictures | false | false |
| 7 | 2 | The Princess and the Frog | $10,716 | -62.1% | 9 | - | $1,190 | $50,051 | 2 | Walt Disney Pictures | false | false |
| 8 | 6 | It's Complicated | $8,171 | -54.5% | 8 | - | $1,021 | $283,354 | 6 | United International Pictures | false | false |
| 9 | 7 | Planet 51 | $3,786 | -72.7% | 10 | - | $378 | $175,048 | 5 | N/A | false | false |
| 10 | 8 | Daybreakers | $1,832 | -36.5% | 4 | - | $458 | $20,803 | 3 | N/A | false | false |
| 11 | 9 | Bad Lieutenant: Port of Call New Orleans | $1,157 | -54.4% | 1 | - | $1,157 | $11,381 | 3 | N/A | false | false |
| 12 | 11 | Sin Nombre | $868 | +12.9% | 1 | - | $868 | $9,309 | 3 | N/A | false | false |
| 13 | 12 | Capitalism: A Love Story | $138 | -61% | 1 | - | $138 | $17,906 | 5 | N/A | false | false |
