| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $2,537,847 | -8.6% | 550 | -45 | $4,614 | $38,827,810 | 6 | 20th Century Fox International | false | false |
| 2 | 2 | Alvin and the Chipmunks: The Squeakquel | $1,750,874 | -30.1% | 391 | -23 | $4,477 | $15,095,139 | 3 | 20th Century Fox International | false | false |
| 3 | 3 | Sherlock Holmes | $1,314,095 | -26% | 308 | -10 | $4,266 | $8,456,985 | 3 | Warner Bros. | false | false |
| 4 | - | Up in the Air | $977,670 | - | 167 | - | $5,854 | $977,670 | 1 | Paramount Pictures International | true | false |
| 5 | - | Tooth Fairy | $859,989 | - | 172 | - | $4,999 | $859,989 | 1 | 20th Century Fox International | true | false |
| 6 | 5 | Xuxa and the Mystery of the Little Ugly Princess | $213,355 | -25.8% | 211 | +2 | $1,011 | $3,732,202 | 5 | PlayArte Pictures | false | false |
| 7 | 4 | Lula, the Son of Brazil | $181,157 | -45.4% | 215 | -68 | $842 | $3,673,418 | 4 | Europa Filmes | false | false |
| 8 | - | Astro Boy | $151,743 | - | 76 | - | $1,996 | $151,743 | 1 | Paris Filmes | true | false |
| 9 | 6 | Bad Lieutenant: Port of Call New Orleans | $107,853 | -55.3% | 68 | -4 | $1,586 | $505,567 | 2 | N/A | false | false |
| 10 | 8 | Hachi: A Dog's Tale | $89,661 | -46.6% | 117 | -8 | $766 | $3,525,893 | 5 | N/A | false | false |
| 11 | 7 | Couples Retreat | $74,402 | -62.7% | 103 | -32 | $722 | $3,558,405 | 5 | Universal Pictures International (UPI) | false | false |
| 12 | - | Chéri | $70,809 | - | 28 | - | $2,528 | $70,809 | 1 | N/A | true | false |
| 13 | 9 | Where the Wild Things Are | $57,545 | -46.9% | 24 | - | $2,397 | $246,164 | 2 | Warner Bros. | false | false |
| 14 | 10 | The Princess and the Frog | $53,301 | -28.9% | 128 | -49 | $416 | $3,890,796 | 7 | Walt Disney Pictures | false | false |
| 15 | 12 | 2012 | $36,429 | -45.9% | 42 | -27 | $867 | $25,586,796 | 11 | Sony Pictures Releasing | false | false |
| 16 | 16 | Broken Embraces | $32,844 | -7% | 29 | +4 | $1,132 | $1,353,154 | 8 | Universal Pictures International (UPI) | false | false |
| 17 | - | Twilight | $28,525 | - | 43 | - | $663 | $27,353,149 | 58 | Paris Filmes | false | false |
| 18 | 26 | Coco Before Chanel | $26,269 | +356.4% | 19 | +13 | $1,382 | $862,615 | 13 | Warner Bros. | false | false |
| 19 | 14 | The Great Buck Howard | $19,122 | -58.1% | 14 | -1 | $1,365 | $96,074 | 2 | Europa Filmes | false | false |
| 20 | 19 | Julie & Julia | $18,964 | -11.6% | 22 | +3 | $862 | $1,149,033 | 9 | Sony Pictures Releasing | false | false |
| 21 | 13 | The Fourth Kind | $17,746 | -64.2% | 36 | -9 | $492 | $799,723 | 4 | N/A | false | false |
| 22 | 18 | Wild Grass | $17,576 | -32.8% | 9 | - | $1,952 | $175,229 | 2 | N/A | false | false |
| 23 | 15 | New York, I Love You | $13,912 | -64% | 16 | -4 | $869 | $476,417 | 6 | N/A | false | false |
| 24 | 23 | Inglourious Basterds | $8,485 | +1.9% | 8 | -2 | $1,060 | $5,040,112 | 16 | Universal Pictures International (UPI) | false | false |
| 25 | 20 | Easy Virtue | $8,220 | -50% | 4 | - | $2,055 | $143,026 | 14 | Sony Pictures Releasing | false | false |
| 26 | 22 | 500 Days of Summer | $7,850 | -8.4% | 13 | +2 | $603 | $1,265,032 | 12 | 20th Century Fox International | false | false |
| 27 | 21 | Paranormal Activity | $6,723 | -45.1% | 29 | -14 | $231 | $5,160,084 | 8 | PlayArte Pictures | false | false |
| 28 | 17 | Motherhood | $3,942 | -88.8% | 9 | -11 | $438 | $67,897 | 2 | Paris Filmes | false | false |
| 29 | 25 | Planet 51 | $3,140 | -48.3% | 27 | -6 | $116 | $2,245,944 | 9 | N/A | false | false |
| 30 | 24 | The Private Lives of Pippa Lee | $2,893 | -53.4% | 3 | -2 | $964 | $81,660 | 6 | PlayArte Pictures | false | false |
| 31 | 30 | A Christmas Carol | $960 | -33.5% | 6 | -4 | $160 | $3,093,042 | 12 | Walt Disney Pictures | false | false |
| 32 | 31 | Saw VI | $726 | -17.8% | 5 | +1 | $145 | $1,834,263 | 12 | Walt Disney Pictures | false | false |
| 33 | 27 | The Edge of Love | $351 | -90.8% | 1 | -6 | $351 | $32,179 | 3 | N/A | false | false |
| 34 | 33 | Cloudy with a Chance of Meatballs | $241 | -40.2% | 2 | -2 | $120 | $7,801,829 | 17 | Sony Pictures Releasing | false | false |
