| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $901,373 | +4.8% | 89 | -3 | $10,127 | $6,261,091 | 4 | 20th Century Fox International | false | false |
| 2 | 2 | Sherlock Holmes | $312,477 | -22.3% | 75 | -1 | $4,166 | $1,761,724 | 3 | Roadshow Films | false | false |
| 3 | 4 | Alvin and the Chipmunks: The Squeakquel | $304,257 | -6.2% | 76 | -7 | $4,003 | $1,695,205 | 3 | 20th Century Fox International | false | false |
| 4 | 3 | The Lovely Bones | $284,568 | -12.8% | 61 | -2 | $4,665 | $1,620,626 | 3 | Paramount Pictures International | false | false |
| 5 | 7 | Paranormal Activity | $262,078 | +405.1% | 42 | +7 | $6,239 | $328,253 | 2 | Icon Film Distribution | false | false |
| 6 | - | Old Dogs | $153,891 | - | 46 | - | $3,345 | $153,891 | 1 | Walt Disney Pictures | true | false |
| 7 | - | Fantastic Mr. Fox | $103,333 | - | 48 | - | $2,152 | $105,579 | 1 | 20th Century Fox International | true | false |
| 8 | 5 | The Princess and the Frog | $87,484 | -12.6% | 59 | -2 | $1,482 | $294,347 | 2 | Walt Disney Pictures | false | false |
| 9 | 6 | The Girl with the Dragon Tattoo | $63,152 | -13.9% | 33 | +2 | $1,913 | $280,688 | 4 | Rialto Distribution | false | false |
| 10 | - | Whip It | $52,374 | - | 39 | - | $1,342 | $52,374 | 1 | Roadshow Films | true | false |
| 11 | - | Cirque du Freak: The Vampire's Assistant | $30,935 | - | 26 | - | $1,189 | $30,935 | 1 | United International Pictures | true | false |
| 12 | 9 | The Twilight Saga: New Moon | $20,496 | -46.2% | 32 | -29 | $640 | $4,437,969 | 8 | Hoyts Distribution | false | false |
| 13 | 8 | 3 Idiots | $19,951 | -50.8% | 5 | - | $3,990 | $153,082 | 3 | Mind Blowing Films | false | false |
| 14 | - | Mid-August Lunch | $17,254 | - | 7 | - | $2,464 | $38,784 | 1 | Rialto Distribution | true | false |
| 15 | 11 | Creation | $15,059 | -14.9% | 22 | -1 | $684 | $73,229 | 3 | Icon Film Distribution | false | false |
| 16 | 10 | Where the Wild Things Are | $12,530 | -55.5% | 21 | -24 | $596 | $897,017 | 6 | Roadshow Films | false | false |
| 17 | 14 | Julie & Julia | $8,940 | -22.6% | 13 | -1 | $687 | $1,394,860 | 12 | Sony Pictures Releasing | false | false |
| 18 | - | Whatever Works | $7,774 | - | 10 | - | $777 | $7,774 | 1 | Hopscotch Films | true | false |
| 19 | 12 | The Time Traveler's Wife | $6,145 | -59.4% | 12 | -12 | $512 | $604,674 | 6 | Roadshow Films | false | false |
| 20 | 13 | Planet 51 | $5,477 | -53.3% | 15 | -20 | $365 | $281,495 | 5 | Hoyts Distribution | false | false |
| 21 | 26 | My Sister's Keeper | $4,859 | +102.3% | 12 | -2 | $404 | $947,138 | 10 | Roadshow Films | false | false |
| 22 | - | Pyaar Impossible | $3,614 | - | 2 | - | $1,807 | $3,614 | 1 | Forum Hungary | true | false |
| 23 | 23 | Five Minutes of Heaven | $3,492 | +0.8% | 8 | - | $436 | $21,976 | 4 | Madman Entertainment | false | false |
| 24 | 17 | Amelia | $2,691 | -63.1% | 9 | -3 | $299 | $123,550 | 5 | 20th Century Fox International | false | false |
| 25 | 27 | In the Loop | $2,532 | +8.3% | 3 | - | $844 | $357,198 | 15 | Madman Entertainment | false | false |
| 26 | 16 | Bodyguards and Assassins | $2,411 | -71.7% | 2 | -1 | $1,205 | $17,950 | 2 | - | false | false |
| 27 | 28 | Mary and Max | $1,548 | +21.2% | 5 | +2 | $309 | $53,081 | 7 | Icon Film Distribution | false | false |
| 28 | 25 | Looking for Eric | $1,348 | -46.3% | 8 | - | $168 | $117,609 | 7 | Icon Film Distribution | false | false |
| 29 | 29 | Valentino: The Last Emperor | $1,108 | +1.2% | 2 | - | $554 | $67,580 | 7 | Hopscotch Films | false | false |
| 30 | 32 | Departures | $1,025 | +45.8% | 8 | +2 | $128 | $199,293 | 21 | Madman Entertainment | false | false |
| 31 | 24 | The Storm Warriors | $1,021 | -61.3% | 1 | -4 | $1,021 | $78,106 | 5 | Vendetta Films | false | false |
| 32 | 30 | Coco Before Chanel | $992 | +9.3% | 2 | - | $496 | $585,372 | 23 | Warner Bros. | false | false |
| 33 | 31 | The Informant! | $965 | +18.4% | 3 | +1 | $321 | $85,576 | 6 | Warner Bros. | false | false |
| 34 | 19 | Bandslam | $857 | -85.4% | 9 | -24 | $95 | $84,828 | 4 | Hoyts Distribution | false | false |
| 35 | 18 | Under the Mountain | $695 | -89.4% | 5 | -21 | $139 | $202,118 | 5 | Walt Disney Pictures | false | false |
| 36 | 33 | A Heavenly Vintage | $484 | -6.2% | 5 | +1 | $96 | $140,726 | 9 | Icon Film Distribution | false | false |
| 37 | - | The Strength of Water | $208 | - | 1 | - | $208 | $163,182 | 20 | Hopscotch Films | false | false |
| 38 | 36 | Surrogates | $147 | +2.8% | 1 | - | $147 | $589,459 | 12 | Walt Disney Pictures | false | false |
| 39 | 35 | The Imaginarium of Doctor Parnassus | $113 | -70.3% | 1 | -2 | $113 | $259,806 | 10 | Hoyts Distribution | false | false |
| 40 | 34 | A Christmas Carol | $43 | -90.5% | 1 | - | $43 | $521,597 | 10 | Walt Disney Pictures | false | false |
| 41 | - | What Just Happened | $12 | - | 1 | - | $12 | $17,756 | 8 | Hopscotch Films | false | false |
