| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Me, Them and Lara | $6,753,283 | - | - | - | - | $11,824,742 | 1 | Warner Bros. | true | false |
| 2 | 1 | Sherlock Holmes | $2,868,913 | -56.4% | - | - | - | $23,958,534 | 3 | Warner Bros. | false | false |
| 3 | - | Surrogates | $1,436,151 | - | - | - | - | $1,436,151 | 1 | Walt Disney Pictures | true | false |
| 4 | 4 | Hachi: A Dog's Tale | $1,351,052 | -45.9% | - | - | - | $5,923,532 | 2 | Lucky Red | false | false |
| 5 | - | The Hedgehog | $965,533 | - | - | - | - | $1,592,380 | 1 | Eagle Pictures | true | false |
| 6 | 6 | Cloudy with a Chance of Meatballs | $876,753 | -52.9% | 295 | -13 | $2,972 | $7,794,543 | 3 | Sony Pictures Releasing | false | false |
| 7 | 5 | The Princess and the Frog | $739,083 | -68.3% | - | - | - | $12,800,985 | 4 | Walt Disney Pictures | false | false |
| 8 | 3 | Me and Marilyn | $685,389 | -82.5% | - | - | - | $18,662,444 | 4 | Medusa Distribuzione | false | false |
| 9 | 2 | Natale a Beverly Hills | $597,176 | -86.3% | - | - | - | $29,936,945 | 4 | Filmauro | false | false |
| 10 | - | Soul Kitchen | $522,725 | - | - | - | - | $567,672 | 1 | BIM Distribuzione | true | false |
| 11 | - | [Rec]² | $472,185 | - | 146 | - | $3,234 | $835,780 | 1 | Sony Pictures Releasing | true | false |
| 12 | 7 | A Christmas Carol | $465,831 | -74% | - | - | - | $24,451,292 | 6 | Walt Disney Pictures | false | false |
| 13 | 9 | Cado dalle nubi | $269,504 | -67.9% | - | - | - | $19,950,141 | 7 | Medusa Distribuzione | false | false |
| 14 | 8 | Brothers | $190,162 | -78% | - | - | - | $3,240,347 | 3 | 01 Distribution | false | false |
| 15 | 10 | Arthur and the Revenge of Maltazard | $129,447 | -65.3% | - | - | - | $763,337 | 2 | N/A | false | false |
| 16 | 12 | Welcome | $116,528 | -49.7% | - | - | - | $987,047 | 5 | Teodora Film | false | false |
| 17 | 13 | Looking for Eric | $98,352 | -48.6% | - | - | - | $1,585,787 | 6 | BIM Distribuzione | false | false |
| 18 | 14 | A Serious Man | $77,566 | -52.2% | - | - | - | $3,569,606 | 6 | Medusa Distribuzione | false | false |
| 19 | 15 | The Cézanne Affair/The Man Who Will Come | $48,575 | -59.2% | - | - | - | $2,246,541 | 6 | 01 Distribution | false | false |
| 20 | 16 | Ten Winters | $47,556 | -48.1% | - | - | - | $688,027 | 5 | N/A | false | false |
| 21 | 21 | Moon | $7,623 | -52% | 3 | -5 | $2,541 | $142,981 | 6 | Sony Pictures Releasing | false | false |
