| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Princess and the Frog | $25,000,000 | $24,208,916 | -$791,084 | -3.2% | 3,434 | $27,880,000 | $27,088,786 | 3 | Walt Disney Studios Motion Pictures | - |
| 2 | 2 | - | The Blind Side | $15,450,000 | $15,055,258 | -$394,742 | -2.6% | 3,388 | $150,212,000 | $149,816,797 | 4 | Warner Bros. | - |
| 3 | 3 | - | Invictus | $9,085,000 | $8,611,147 | -$473,853 | -5.2% | 2,125 | $9,085,000 | $8,611,147 | 1 | Warner Bros. | - |
| 4 | 4 | - | The Twilight Saga: New Moon | $8,000,000 | $7,960,394 | -$39,606 | -0.5% | 3,635 | $267,360,000 | $267,320,977 | 4 | Summit Entertainment | - |
| 5 | 5 | - | A Christmas Carol | $6,871,000 | $6,833,190 | -$37,810 | -0.6% | 2,402 | $124,464,000 | $124,426,097 | 6 | Walt Disney Studios Motion Pictures | - |
| 6 | 6 | - | Brothers | $5,000,000 | $5,014,426 | +$14,426 | +0.3% | 2,088 | $17,402,000 | $17,416,217 | 2 | Lionsgate | - |
| 7 | 8 | +1 | 2012 | $4,400,000 | $4,351,565 | -$48,435 | -1.1% | 2,838 | $155,337,000 | $155,288,405 | 5 | Sony Pictures Releasing | - |
| 8 | 7 | -1 | Old Dogs | $4,396,000 | $4,409,772 | +$13,772 | +0.3% | 3,090 | $39,983,000 | $39,996,273 | 3 | Walt Disney Studios Motion Pictures | - |
| 9 | 9 | - | Armored | $3,500,000 | $3,504,374 | +$4,374 | +0.1% | 1,919 | $11,747,000 | $11,750,895 | 2 | Screen Gems | - |
| 10 | 10 | - | Ninja Assassin | $2,710,000 | $2,707,470 | -$2,530 | <0.1% | 2,100 | $34,307,000 | $34,304,761 | 3 | Warner Bros. | - |
| 11 | 11 | - | Up in the Air | $2,450,000 | $2,394,344 | -$55,656 | -2.3% | 72 | $4,038,000 | $3,982,627 | 2 | Paramount Pictures | - |
| 12 | 12 | - | Planet 51 | $2,300,000 | $2,267,038 | -$32,962 | -1.4% | 2,570 | $37,175,000 | $37,142,406 | 4 | Sony Pictures Releasing | - |
| 13 | 13 | - | Everybody's Fine | $2,235,000 | $2,194,210 | -$40,790 | -1.8% | 2,141 | $7,368,000 | $7,327,877 | 2 | Miramax | - |
| 14 | 14 | - | Fantastic Mr. Fox | $1,400,000 | $1,396,148 | -$3,852 | -0.3% | 1,268 | $16,262,000 | $16,258,464 | 5 | Twentieth Century Fox | - |
| 15 | 15 | - | Precious | $1,250,000 | $1,280,550 | +$30,550 | +2.4% | 664 | $38,252,000 | $38,282,489 | 6 | Lionsgate | - |
| 16 | 16 | - | The Boondock Saints II: All Saints Day | $780,000 | $793,393 | +$13,393 | +1.7% | 524 | $8,462,000 | $8,475,017 | 7 | Apparition | - |
| 17 | 17 | - | The Road | $498,000 | $505,878 | +$7,878 | +1.6% | 135 | $4,004,000 | $4,012,327 | 3 | Dimension Films | - |
| 18 | 18 | - | An Education | $315,000 | $314,439 | -$561 | -0.2% | 224 | $6,754,000 | $6,752,785 | 10 | Sony Pictures Classics | - |
| 19 | 19 | - | Couples Retreat | $252,000 | $257,820 | +$5,820 | +2.3% | 371 | $107,587,000 | $107,592,235 | 10 | Universal Pictures | - |
| 20 | 21 | +1 | A Single Man | $216,000 | $217,332 | +$1,332 | +0.6% | 9 | $216,000 | $217,332 | 1 | The Weinstein Company | - |
| 21 | 25 | +4 | Me and Orson Welles | $176,000 | $154,754 | -$21,246 | -12.1% | 64 | $343,000 | $321,429 | 3 | Freestyle Releasing | - |
| 22 | 23 | +1 | The Boat That Rocked | $174,000 | $174,293 | +$293 | +0.2% | 242 | $7,683,000 | $7,683,890 | 5 | Focus Features | - |
| 23 | 27 | +4 | Bad Lieutenant: Port of Call New Orleans | $151,000 | $146,292 | -$4,708 | -3.1% | 96 | $1,164,000 | $1,159,281 | 4 | First Look International | - |
| 24 | 26 | +2 | A Serious Man | $142,000 | $146,347 | +$4,347 | +3.1% | 152 | $8,718,000 | $8,717,496 | 11 | Focus Features | - |
| 25 | 28 | +3 | The Fourth Kind | $138,000 | $142,115 | +$4,115 | +3% | 217 | $25,142,000 | $25,145,900 | 6 | Universal Pictures | - |
| 26 | 30 | +4 | The Lovely Bones | $116,000 | $116,616 | +$616 | +0.5% | 3 | $116,000 | $116,616 | 1 | DreamWorks | - |
| 27 | 31 | +4 | Broken Embraces | $115,000 | $109,530 | -$5,470 | -4.8% | 6 | $602,000 | $596,723 | 4 | Sony Pictures Classics | - |
| 28 | 36 | +8 | Paranormal Activity | $55,000 | $61,704 | +$6,704 | +12.2% | 182 | $107,478,000 | $107,484,801 | 12 | Paramount Pictures | - |
| 29 | 37 | +8 | The Messenger | $45,000 | $45,204 | +$204 | +0.5% | 50 | $541,578 | $541,782 | 5 | Oscilloscope | - |
| 30 | 38 | +8 | Astro Boy | $44,000 | $44,232 | +$232 | +0.5% | 122 | $19,073,000 | $19,073,382 | 8 | Summit Entertainment | - |
| 31 | 41 | +10 | Coco Before Chanel | $35,300 | $38,522 | +$3,222 | +9.1% | 68 | $5,882,000 | $5,884,975 | 12 | Sony Pictures Classics | - |
| 32 | 43 | +11 | La Danse: The Paris Opera Ballet | $35,200 | $32,720 | -$2,480 | -7% | 20 | $287,000 | $283,995 | 6 | Zipporah Films | - |
| 33 | 45 | +12 | Inglourious Basterds | $23,000 | $23,791 | +$791 | +3.4% | 61 | $120,523,000 | $120,523,073 | 17 | The Weinstein Company | - |
| 34 | 53 | +19 | New York, I Love You | $16,500 | $17,459 | +$959 | +5.8% | 27 | $1,568,000 | $1,569,133 | 9 | Vivendi Entertainment | - |
| 35 | 54 | +19 | Transylmania | $15,400 | $16,018 | +$618 | +4% | 118 | $390,000 | $390,486 | 2 | Full Circle Releasing | - |
