| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Twilight Saga: New Moon | $42,500,000 | $42,870,031 | +$370,031 | +0.9% | 4,042 | $230,674,000 | $230,947,696 | 2 | Summit Entertainment | - |
| 2 | 2 | - | The Blind Side | $40,125,000 | $40,111,364 | -$13,636 | <0.1% | 3,140 | $100,250,000 | $100,238,841 | 2 | Warner Bros. | - |
| 3 | 3 | - | 2012 | $18,000,000 | $17,651,729 | -$348,271 | -1.9% | 3,444 | $138,776,000 | $138,451,427 | 3 | Sony Pictures Releasing | - |
| 4 | 4 | - | Old Dogs | $16,846,000 | $16,894,511 | +$48,511 | +0.3% | 3,425 | $24,085,000 | $24,228,546 | 1 | Walt Disney Studios Motion Pictures | - |
| 5 | 5 | - | A Christmas Carol | $16,003,000 | $15,758,273 | -$244,727 | -1.5% | 3,013 | $105,373,000 | $104,927,816 | 4 | Walt Disney Studios Motion Pictures | - |
| 6 | 6 | - | Ninja Assassin | $13,135,000 | $13,316,158 | +$181,158 | +1.4% | 2,503 | $21,010,000 | $21,193,565 | 1 | Warner Bros. | - |
| 7 | 7 | - | Planet 51 | $10,200,000 | $10,218,641 | +$18,641 | +0.2% | 3,035 | $28,487,000 | $28,487,409 | 2 | Sony Pictures Releasing | - |
| 8 | 8 | - | Precious | $7,090,000 | $7,081,032 | -$8,968 | -0.1% | 663 | $32,461,000 | $32,433,482 | 4 | Lionsgate | - |
| 9 | 9 | - | Fantastic Mr. Fox | $7,020,000 | $6,965,267 | -$54,733 | -0.8% | 2,033 | $10,108,000 | $10,024,072 | 3 | Twentieth Century Fox | - |
| 10 | 11 | +1 | The Men Who Stare at Goats | $1,533,000 | $1,501,837 | -$31,163 | -2% | 1,119 | $30,552,000 | $30,521,930 | 4 | Overture Films | - |
| 11 | 10 | -1 | The Road | $1,523,000 | $1,502,231 | -$20,769 | -1.4% | 111 | $2,001,000 | $1,977,453 | 1 | Dimension Films | - |
| 12 | 12 | - | The Boondock Saints II: All Saints Day | $1,250,000 | $1,301,197 | +$51,197 | +4.1% | 373 | $5,677,000 | $5,722,723 | 5 | Apparition | - |
| 13 | 13 | - | The Boat That Rocked | $1,046,000 | $989,260 | -$56,740 | -5.4% | 478 | $6,889,000 | $6,830,855 | 3 | Focus Features | - |
| 14 | 14 | - | Couples Retreat | $974,000 | $960,995 | -$13,005 | -1.3% | 862 | $106,722,000 | $106,700,205 | 8 | Universal Pictures | - |
| 15 | 15 | - | An Education | $974,000 | $911,388 | -$62,612 | -6.4% | 265 | $5,620,000 | $5,563,649 | 8 | Sony Pictures Classics | - |
| 16 | 17 | +1 | Law Abiding Citizen | $808,000 | $786,534 | -$21,466 | -2.7% | 584 | $71,524,000 | $71,505,530 | 7 | Overture Films | - |
| 17 | 16 | -1 | This Is It | $800,000 | $828,976 | +$28,976 | +3.6% | 576 | $71,800,000 | $71,844,424 | 5 | Sony Pictures Releasing | - |
| 18 | 18 | - | The Princess and the Frog | $712,000 | $786,190 | +$74,190 | +10.4% | 2 | $1,142,000 | $1,216,860 | 1 | Walt Disney Studios Motion Pictures | - |
| 19 | 19 | - | The Fourth Kind | $627,000 | $618,265 | -$8,735 | -1.4% | 552 | $24,619,000 | $24,605,935 | 4 | Universal Pictures | - |
| 20 | 21 | +1 | Paranormal Activity | $505,000 | $486,190 | -$18,810 | -3.7% | 725 | $107,132,000 | $107,113,212 | 10 | Paramount Pictures | - |
| 21 | 22 | +1 | A Serious Man | $495,000 | $478,235 | -$16,765 | -3.4% | 173 | $8,183,000 | $8,163,478 | 9 | Focus Features | - |
| 22 | 24 | +2 | Bad Lieutenant: Port of Call New Orleans | $296,000 | $291,464 | -$4,536 | -1.5% | 57 | $692,000 | $687,631 | 2 | First Look International | - |
| 23 | 26 | +3 | Coco Before Chanel | $203,000 | $197,578 | -$5,422 | -2.7% | 145 | $5,595,000 | $5,627,432 | 10 | Sony Pictures Classics | - |
| 24 | 29 | +5 | The Messenger | $155,000 | $140,203 | -$14,797 | -9.5% | 40 | $368,000 | $353,303 | 3 | Oscilloscope | - |
| 25 | 27 | +2 | Astro Boy | $151,000 | $172,892 | +$21,892 | +14.5% | 287 | $18,909,000 | $18,922,566 | 6 | Summit Entertainment | - |
| 26 | 33 | +7 | Broken Embraces | $117,000 | $117,986 | +$986 | +0.8% | 2 | $312,000 | $312,966 | 2 | Sony Pictures Classics | - |
| 27 | 38 | +11 | The Private Lives of Pippa Lee | $96,000 | $89,950 | -$6,050 | -6.3% | 12 | $96,000 | $89,950 | 1 | Screen Media Films | - |
| 28 | 41 | +13 | Me and Orson Welles | $64,800 | $63,638 | -$1,162 | -1.8% | 4 | $86,600 | $85,422 | 1 | Freestyle Releasing | - |
| 29 | 42 | +13 | Inglourious Basterds | $58,300 | $56,456 | -$1,844 | -3.2% | 102 | $120,376,000 | $120,381,050 | 15 | The Weinstein Company | - |
| 30 | 45 | +15 | La Danse: The Paris Opera Ballet | $52,500 | $48,550 | -$3,950 | -7.5% | 13 | $184,000 | $179,642 | 4 | Zipporah Films | - |
| 31 | 47 | +16 | Fame | $46,000 | $45,437 | -$563 | -1.2% | 146 | $22,431,000 | $22,429,956 | 10 | Metro-Goldwyn-Mayer (MGM) | - |
| 32 | 55 | +23 | 9 | $27,400 | $29,189 | +$1,789 | +6.5% | 63 | $31,742,000 | $31,743,332 | 12 | Focus Features | - |
