| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Twilight Saga: New Moon | $2,634,791 | - | 89 | - | $29,604 | $2,634,791 | 1 | Belga Films | true | false |
| 2 | 1 | 2012 | $1,101,042 | -46.8% | 98 | +4 | $11,235 | $3,517,710 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | A Christmas Carol | $322,090 | - | 66 | - | $4,880 | $401,017 | 1 | Walt Disney Pictures | true | false |
| 4 | 3 | Das Lied der Dinge | $197,284 | -34.6% | 31 | - | $6,364 | $3,081,160 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 5 | 2 | Up | $181,507 | -68% | 120 | -12 | $1,512 | $6,687,796 | 7 | Walt Disney Pictures | false | false |
| 6 | 12 | The Concert | $134,736 | +37.3% | 14 | +3 | $9,624 | $239,777 | 2 | Cinéart | false | false |
| 7 | 6 | The Barons | $122,657 | -27.3% | 10 | -1 | $12,265 | $520,570 | 3 | Cinéart | false | false |
| 8 | 5 | The Box | $99,396 | -46.5% | 28 | - | $3,549 | $693,467 | 3 | Benelux Film Distributors | false | false |
| 9 | - | Twilight | $93,631 | - | 35 | - | $2,675 | $3,828,564 | 52 | Belga Films | false | false |
| 10 | 4 | This Is It | $89,359 | -69.6% | 54 | -8 | $1,654 | $2,735,951 | 4 | Sony Pictures Releasing | false | false |
| 11 | - | Love Happens | $78,232 | - | 16 | - | $4,889 | $87,517 | 1 | A-Film Distribution | true | false |
| 12 | 7 | Trésor | $61,159 | -53.5% | 14 | - | $4,368 | $237,435 | 2 | Alternative Films | false | false |
| 13 | 9 | Little Nicholas | $45,984 | -59.7% | 30 | +2 | $1,532 | $1,755,428 | 8 | Cinéart | false | false |
| 14 | - | The Informant! | $45,129 | - | 7 | - | $6,447 | $96,069 | 1 | Warner Bros. | true | false |
| 15 | 10 | The Rebound | $38,079 | -65.9% | 24 | -3 | $1,586 | $266,291 | 2 | Paradiso Entertainment | false | false |
| 16 | 16 | Sinterklaas en de verdwenen pakjesboot | $36,695 | -26.4% | 16 | +3 | $2,293 | $194,553 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | 13 | Surrogates | $28,651 | -66.2% | 24 | -16 | $1,193 | $1,183,772 | 5 | Walt Disney Pictures | false | false |
| 18 | 14 | Astro Boy | $27,404 | -61.5% | 36 | -7 | $761 | $423,407 | 4 | Belga Films | false | false |
| 19 | 19 | The White Ribbon | $25,016 | -44.3% | 16 | -1 | $1,563 | $351,394 | 5 | Cinéart | false | false |
| 20 | 8 | Cirque du Freak: The Vampire's Assistant | $23,653 | -79.9% | 26 | -4 | $909 | $501,992 | 3 | Universal Pictures International (UPI) | false | false |
| 21 | 15 | Inglourious Basterds | $21,878 | -57.2% | 14 | -9 | $1,562 | $5,184,122 | 14 | Universal Pictures International (UPI) | false | false |
| 22 | 11 | Fame | $21,340 | -78.3% | 35 | -9 | $609 | $1,928,562 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 23 | 17 | 500 Days of Summer | $15,952 | -67.4% | 7 | -4 | $2,278 | $185,153 | 3 | 20th Century Fox International | false | false |
| 24 | 22 | G-Force | $12,187 | -65.1% | 12 | -2 | $1,015 | $3,055,576 | 17 | Walt Disney Pictures | false | false |
| 25 | 24 | Lilly the Witch: The Dragon and the Magic Book | $10,585 | -62% | 10 | - | $1,058 | $180,503 | 40 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | 20 | Micmacs | $9,942 | -76% | 24 | -12 | $414 | $394,005 | 4 | Cinéart | false | false |
| 27 | - | Departures | $8,688 | - | 6 | - | $1,448 | $37,491 | 3 | N/A | false | false |
| 28 | - | Wild Grass | $8,397 | - | 5 | - | $1,679 | $40,655 | 3 | N/A | false | false |
| 29 | 25 | The Ugly Truth | $7,889 | -66.1% | 6 | -14 | $1,314 | $1,541,791 | 9 | Sony Pictures Releasing | false | false |
| 30 | 18 | Dance Flick | $6,481 | -86.5% | 12 | -7 | $540 | $437,491 | 4 | Universal Pictures International (UPI) | false | false |
| 31 | - | My Queen Karo | $6,376 | - | 7 | - | $910 | $102,161 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 23 | Lucky Luke | $6,185 | -81.1% | 16 | -8 | $386 | $465,170 | 5 | Les Films de l'Elysée | false | false |
| 33 | - | Whatever Works | $5,205 | - | 5 | - | $1,041 | $395,542 | 8 | Paradiso Entertainment | false | false |
| 34 | 21 | Jennifer's Body | $5,077 | -85.9% | 19 | -12 | $267 | $572,830 | 5 | 20th Century Fox International | false | false |
