| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | This Is It | $28,470 | -49.1% | 6 | - | $4,745 | $107,042 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | The Box | $16,072 | - | 2 | - | $8,036 | $16,072 | 1 | ACME | true | false |
| 3 | 2 | Cloudy with a Chance of Meatballs | $15,325 | -39.8% | 10 | - | $1,532 | $127,249 | 3 | Sony Pictures Releasing | false | false |
| 4 | - | OceanWorld | $13,570 | - | 1 | - | $13,570 | $13,570 | 1 | ACME | true | false |
| 5 | 3 | Saw VI | $8,946 | -58.7% | 3 | - | $2,982 | $40,784 | 2 | ACME | false | false |
| 6 | 5 | The Ugly Truth | $6,990 | -15.3% | 4 | - | $1,747 | $191,241 | 7 | Sony Pictures Releasing | false | false |
| 7 | 4 | G-Force | $5,725 | -38.3% | 13 | - | $440 | $186,501 | 6 | - | false | false |
| 8 | 7 | Surrogates | $5,076 | -14.1% | 4 | - | $1,269 | $67,813 | 4 | - | false | false |
| 9 | 8 | 3 of Us | $4,852 | -17.8% | 2 | +1 | $2,426 | $20,173 | 2 | N/A | false | false |
| 10 | 11 | Julie & Julia | $3,547 | -10% | 1 | - | $3,547 | $47,807 | 5 | Sony Pictures Releasing | false | false |
| 11 | 6 | Orphan | $3,526 | -41.3% | 3 | - | $1,175 | $29,190 | 3 | ACME | false | false |
| 12 | 10 | Antichrist | $3,213 | -23.8% | 1 | - | $3,213 | $22,740 | 3 | ACME | false | false |
| 13 | 12 | The Time Traveler's Wife | $3,139 | -2.8% | 1 | - | $3,139 | $37,385 | 4 | - | false | false |
| 14 | 13 | Shrink | $1,937 | +0.4% | 1 | - | $1,937 | $31,712 | 6 | ACME | false | false |
| 15 | 9 | The Final Destination | $1,357 | -74.7% | 1 | - | $1,357 | $178,007 | 8 | - | false | false |
| 16 | 15 | High Security Vacation | $937 | -28.5% | 2 | - | $468 | $113,645 | 11 | ACME | false | false |
| 17 | 16 | Ice Age: Dawn of the Dinosaurs | $822 | -22.3% | 12 | - | $68 | $813,878 | 19 | - | false | false |
| 18 | 14 | Up | $818 | -47% | 9 | - | $90 | $257,397 | 14 | - | false | false |
| 19 | 17 | Pandorum | $320 | -63.3% | 2 | - | $160 | $23,990 | 5 | ACME | false | false |
