| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | This Is It | $73,040 | - | 14 | - | $5,217 | $73,040 | 1 | Alexandra Films | true | false |
| 2 | 1 | Cloudy with a Chance of Meatballs | $60,680 | -25.5% | 17 | - | $3,569 | $166,184 | 2 | Alexandra Films | false | false |
| 3 | - | Saw VI | $28,641 | - | 7 | - | $4,091 | $28,641 | 1 | Sunny Films | true | false |
| 4 | 3 | The Accidental Husband | $15,586 | -11.4% | 8 | - | $1,948 | $39,561 | 2 | A Plus Films | false | false |
| 5 | 4 | Whiteout | $9,828 | -33.7% | 9 | -5 | $1,092 | $78,394 | 3 | Alexandra Films | false | false |
| 6 | 8 | Eastern Plays | $7,302 | +9.5% | 7 | - | $1,043 | $58,605 | 3 | - | false | false |
| 7 | 7 | Up | $6,587 | -9.3% | 7 | +3 | $941 | $251,319 | 6 | Sunny Films | false | false |
| 8 | 6 | Surrogates | $5,278 | -35.4% | 8 | -4 | $659 | $151,180 | 5 | Sunny Films | false | false |
| 9 | - | Coco Before Chanel | $5,267 | - | 5 | - | $1,053 | $97,012 | - | - | - | false |
| 10 | 16 | The Final Destination | $2,912 | +121.3% | 3 | +1 | $970 | $261,459 | 9 | Alexandra Films | false | false |
| 11 | 10 | The Brothers Bloom | $2,847 | -36.5% | 6 | - | $474 | $30,067 | 12 | Sunny Films | false | false |
| 12 | 9 | Funny People | $2,651 | -47.2% | 6 | - | $441 | $28,969 | 3 | Prooptiki | false | false |
| 13 | 11 | Julie & Julia | $2,104 | -38.6% | 4 | - | $526 | $25,912 | 3 | Alexandra Films | false | false |
| 14 | 12 | Year One | $2,065 | -29.1% | 8 | -1 | $258 | $63,452 | 11 | Alexandra Films | false | false |
| 15 | 21 | The World is Big and Salvation Lurks Around the Corner | $589 | +147.5% | 3 | +2 | $196 | $108,371 | 56 | Alexandra Films | false | false |
| 16 | 17 | Inglourious Basterds | $575 | -27.3% | 4 | -1 | $143 | $320,895 | 10 | Prooptiki | false | false |
| 17 | - | Gucha: Distant Trumpet | $454 | - | 1 | - | $454 | $13,473 | 138 | Art Fest | false | false |
| 18 | - | The Unborn | $359 | - | 2 | - | $179 | $43,575 | 37 | United International Pictures | false | false |
| 19 | - | Underworld: Rise of the Lycans | $295 | - | 2 | - | $147 | $164,969 | 41 | Alexandra Films | false | false |
| 20 | - | X-Men Origins: Wolverine | $295 | - | 1 | - | $295 | $199,456 | 27 | Alexandra Films | false | false |
| 21 | - | Drag Me to Hell | $258 | - | 3 | - | $86 | $40,191 | 11 | A-Film Distribution | false | false |
| 22 | - | Angels & Demons | $247 | - | 2 | - | $123 | $639,449 | 25 | Alexandra Films | false | false |
| 23 | 26 | The Time Traveler's Wife | $236 | +202.6% | 1 | -1 | $236 | $38,229 | 7 | Alexandra Films | false | false |
| 24 | - | Saw V | $225 | - | 2 | - | $112 | $74,830 | 53 | Sunny Films | false | false |
| 25 | 18 | Ice Age: Dawn of the Dinosaurs | $191 | -70.4% | 2 | - | $95 | $1,927,358 | 18 | 20th Century Fox International | false | false |
| 26 | 23 | The Goat | $120 | -24.1% | 2 | -2 | $60 | $6,685 | 5 | - | false | false |
| 27 | - | Watchmen | $105 | - | 1 | - | $105 | $108,274 | 34 | United International Pictures | false | false |
| 28 | - | Transformers: Revenge of the Fallen | $89 | - | 1 | - | $89 | $264,041 | 19 | Prooptiki | false | false |
| 29 | 28 | G-Force | $73 | +7.4% | 3 | +1 | $24 | $249,278 | 14 | Sunny Films | false | false |
| 30 | 31 | The Tale of Despereaux | $32 | +60% | 1 | - | $32 | $90,850 | 41 | United International Pictures | false | false |
| 31 | 22 | District 9 | $30 | -81.8% | 4 | -1 | $7 | $64,780 | 7 | A Plus Films | false | false |
| 32 | 20 | The Good the Bad the Weird | $27 | -89.7% | 1 | -2 | $27 | $3,337 | 4 | - | false | false |
| 33 | 29 | In Bruges | $23 | -17.9% | 1 | - | $23 | $17,531 | 32 | Prooptiki | false | false |
| 34 | - | Che: Part Two | $15 | - | 1 | - | $15 | $1,748 | 26 | Alexandra Films | false | false |
| 35 | - | Revolutionary Road | $14 | - | 1 | - | $14 | $23,605 | 36 | United International Pictures | false | false |
| 36 | - | Che: Part One/Che: Part Two | $14 | - | 1 | - | $14 | $19,138 | 13 | Alexandra Films | false | false |
| 37 | 19 | The Ugly Truth | $12 | -97.5% | 1 | -2 | $12 | $228,662 | 6 | Alexandra Films | false | false |
| 38 | 34 | Love in the Time of Cholera | $9 | - | 1 | - | $9 | $38,234 | 75 | Prooptiki | false | false |
| 39 | 33 | My Life in Ruins | $6 | -60% | 1 | - | $6 | $92,138 | 13 | Forum Hungary | false | false |
| 40 | - | Deception | $4 | - | 1 | - | $4 | $13,646 | - | Prooptiki | - | false |
