| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | This Is It | $565,725 | - | 100 | - | $5,657 | $565,725 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Patient X | $242,075 | - | 65 | - | $3,724 | $3,724 | 1 | N/A | true | false |
| 3 | - | Jennifer's Body | $135,568 | - | 29 | - | $4,674 | $135,568 | 1 | 20th Century Fox International | true | false |
| 4 | 1 | 500 Days of Summer | $87,435 | -39.8% | 15 | - | $5,829 | $270,311 | 2 | 20th Century Fox International | false | false |
| 5 | - | Astro Boy | $77,757 | - | 22 | - | $3,534 | $77,757 | 1 | Pioneer Films | true | false |
| 6 | 3 | Carriers | $35,169 | -48.1% | 14 | - | $2,512 | $121,981 | 2 | Pioneer Films | false | false |
| 7 | 5 | Red Cliff | $24,228 | -55.2% | 22 | -8 | $1,101 | $260,309 | 3 | Viva International Pictures | false | false |
| 8 | 2 | G-Force | $23,079 | -70.5% | 19 | -29 | $1,214 | $773,915 | 4 | Walt Disney Pictures | false | false |
| 9 | 4 | Halloween II | $20,917 | -68.6% | 20 | - | $1,045 | $106,199 | 2 | Viva International Pictures | false | false |
| 10 | 9 | Battle for Terra | $9,725 | -51.3% | 10 | - | $972 | $35,316 | 2 | Viva International Pictures | false | false |
| 11 | 6 | The Hurt Locker | $9,159 | -74.8% | 17 | - | $538 | $55,730 | 2 | Pioneer Films | false | false |
| 12 | 13 | The Informant! | $6,365 | -50.7% | 2 | - | $3,182 | $21,830 | 2 | Warner Bros. | false | false |
| 13 | 8 | Yaya & Angelina: The Spoiled Brat Movie | $4,213 | -80.1% | 9 | -3 | $468 | $1,350,422 | 6 | N/A | false | false |
| 14 | - | The Echo | $1,886 | - | 6 | - | $314 | $127,011 | 3 | Viva International Pictures | false | false |
| 15 | 12 | Surrogates | $1,655 | -90.3% | 5 | -14 | $331 | $925,230 | 6 | Walt Disney Pictures | false | false |
| 16 | 17 | Whiteout | $290 | -85.5% | 2 | -5 | $145 | $198,812 | 7 | Warner Bros. | false | false |
| 17 | 18 | Harry Potter and the Half-Blood Prince | $280 | -72.6% | 2 | - | $140 | $4,014,548 | 16 | Warner Bros. | false | false |
| 18 | 11 | The Ugly Truth | $239 | -98.7% | 1 | -12 | $239 | $532,926 | 5 | Sony Pictures Releasing | false | false |
