| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Up | $4,563,789 | -31.5% | 624 | -28 | $7,313 | $13,808,348 | 2 | Walt Disney Pictures | false | false |
| 2 | - | The Imaginarium of Doctor Parnassus | $2,688,670 | - | 227 | - | $11,844 | $2,689,085 | 1 | N/A | true | false |
| 3 | - | Just Married | $1,410,618 | - | 378 | - | $3,731 | $1,411,856 | 1 | United International Pictures | true | false |
| 4 | 2 | Inglourious Basterds | $948,119 | -45.8% | 262 | -131 | $3,618 | $12,084,930 | 4 | United International Pictures | false | false |
| 5 | - | Julie & Julia | $844,188 | - | 153 | - | $5,517 | $844,188 | 1 | Sony Pictures Releasing | true | false |
| 6 | - | Brüno | $790,843 | - | 239 | - | $3,308 | $791,704 | 1 | Medusa Distribuzione | true | false |
| 7 | - | Red Cliff | $759,792 | - | 248 | - | $3,063 | $759,792 | 1 | Eagle Pictures | true | false |
| 8 | 3 | Baaria | $537,935 | -55.5% | 198 | -164 | $2,716 | $14,901,392 | 5 | Medusa Distribuzione | false | false |
| 9 | 6 | Lo spazio bianco | $290,905 | -45% | 143 | -14 | $2,034 | $1,049,423 | 2 | 01 Distribution | false | false |
| 10 | 8 | Whatever Works | $253,399 | -41.5% | 58 | -47 | $4,368 | $6,953,183 | 6 | Medusa Distribuzione | false | false |
| 11 | 10 | Purple Sea | $229,082 | -13.5% | 101 | +15 | $2,268 | $645,378 | 2 | Medusa Distribuzione | false | false |
| 12 | 7 | Orphan | $227,942 | -55.1% | 103 | -53 | $2,213 | $951,966 | 2 | Warner Bros. | false | false |
| 13 | 5 | Halloween II | $208,084 | -64.8% | 126 | -81 | $1,651 | $1,014,224 | 2 | Sony Pictures Releasing | false | false |
| 14 | - | Lebanon | $139,240 | - | 47 | - | $2,962 | $139,240 | 1 | BIM Distribuzione | true | false |
| 15 | 4 | Fame | $134,274 | -78.2% | 94 | -177 | $1,428 | $2,462,242 | 3 | Lucky Red | false | false |
| 16 | 9 | My Life in Ruins | $72,177 | -75.4% | 56 | -56 | $1,288 | $1,081,008 | 3 | N/A | false | false |
| 17 | 12 | The Double Hour | $50,379 | -78.9% | 34 | - | $1,481 | $1,111,313 | 3 | Medusa Distribuzione | false | false |
| 18 | - | I, Don Giovanni | $47,734 | - | 21 | - | $2,273 | $47,734 | 1 | Lucky Red | true | false |
| 19 | 15 | Taking Woodstock | $42,170 | -65.6% | 15 | - | $2,811 | $564,999 | 3 | BIM Distribuzione | false | false |
| 20 | 14 | G-Force | $32,854 | -75% | 40 | - | $821 | $5,953,876 | 5 | Walt Disney Pictures | false | false |
| 21 | 16 | Ice Age: Dawn of the Dinosaurs | $29,594 | -69.5% | 28 | - | $1,056 | $43,125,448 | 9 | 20th Century Fox International | false | false |
| 22 | 18 | The Taking of Pelham 123 | $22,095 | -71.7% | 10 | -18 | $2,209 | $3,478,075 | 6 | Sony Pictures Releasing | false | false |
| 23 | 11 | Sword of War | $21,399 | -91.7% | 20 | - | $1,069 | $1,189,887 | 3 | 01 Distribution | false | false |
| 24 | - | Turtle: The Incredible Journey | $15,206 | - | 15 | - | $1,013 | $15,206 | 1 | N/A | true | false |
| 25 | - | A Summer in Genoa | $15,034 | - | 6 | - | $2,505 | $55,209 | 2 | N/A | false | false |
| 26 | 19 | The Girl Who Played with Fire | $12,369 | -81.2% | 9 | - | $1,374 | $2,055,044 | 5 | BIM Distribuzione | false | false |
| 27 | 17 | District 9 | $12,060 | -87.3% | 13 | -38 | $927 | $2,741,154 | 5 | Sony Pictures Releasing | false | false |
| 28 | 20 | Ricky | $11,193 | -74% | 10 | - | $1,119 | $170,496 | 3 | Teodora Film | false | false |
| 29 | - | Tinker Bell and the Lost Treasure | $6,794 | - | 24 | - | $283 | $65,942 | 4 | Walt Disney Pictures | false | false |
| 30 | - | The Big Dream | $6,720 | - | 7 | - | $960 | $4,572,264 | 7 | Medusa Distribuzione | false | false |
| 31 | - | The Boat That Rocked | $5,616 | - | 1 | - | $5,616 | $1,383,446 | 20 | United International Pictures | false | false |
| 32 | - | Tales from the Golden Age | $5,393 | - | 5 | - | $1,078 | $156,664 | 6 | N/A | false | false |
| 33 | - | Di me cosa ne sai | $3,994 | - | 4 | - | $998 | $12,884 | 2 | N/A | false | false |
| 34 | 13 | Funny People | $3,985 | -97.3% | 4 | - | $996 | $196,082 | 2 | United International Pictures | false | false |
