| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | This Is It | $358,140 | - | 25 | - | $14,325 | $358,140 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Cloudy with a Chance of Meatballs | $74,043 | -57.5% | 28 | -13 | $2,644 | $597,444 | 3 | Sony Pictures Releasing | false | false |
| 3 | 2 | Inglourious Basterds | $55,848 | -53.8% | 21 | -3 | $2,659 | $492,884 | 3 | United International Pictures | false | false |
| 4 | 3 | The Ugly Truth | $29,909 | -59.2% | 18 | -12 | $1,661 | $616,261 | 4 | Sony Pictures Releasing | false | false |
| 5 | 5 | The Proposal | $10,461 | -38.5% | 3 | -4 | $3,487 | $867,658 | 11 | Walt Disney Pictures | false | false |
| 6 | 4 | Surrogates | $8,827 | -56.4% | 5 | -8 | $1,765 | $897,884 | 5 | Walt Disney Pictures | false | false |
| 7 | - | G-Force | $7,622 | - | 3 | - | $2,540 | $1,200,491 | 7 | Walt Disney Pictures | false | false |
| 8 | 10 | Harry Potter and the Half-Blood Prince | $6,703 | +4,522.8% | 3 | +2 | $2,234 | $3,738,732 | 16 | Warner Bros. | false | false |
| 9 | 6 | G.I. Joe: The Rise of Cobra | $3,519 | -45.7% | 2 | -2 | $1,759 | $2,165,544 | 13 | United International Pictures | false | false |
| 10 | 8 | Whiteout | $849 | -77.8% | 2 | -4 | $424 | $170,024 | 4 | Warner Bros. | false | false |
| 11 | 7 | Public Enemies | $733 | -87.3% | 1 | -1 | $733 | $732,577 | 15 | United International Pictures | false | false |
