| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | This Is It | $1,053,902 | - | 62 | - | $16,998 | $1,053,902 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Up | $577,362 | -21.9% | 130 | -1 | $4,441 | $4,151,744 | 4 | Walt Disney Pictures | false | false |
| 3 | 2 | Das Lied der Dinge | $386,084 | -11.4% | 31 | - | $12,454 | $1,860,481 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 4 | 3 | Surrogates | $289,932 | -11.4% | 53 | +9 | $5,470 | $685,617 | 2 | Walt Disney Pictures | false | false |
| 5 | 4 | Fame | $178,306 | -28.5% | 46 | -1 | $3,876 | $1,389,980 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 6 | - | Micmacs | $149,818 | - | 45 | - | $3,329 | $155,282 | 1 | Cinéart | true | false |
| 7 | - | Dance Flick | $135,666 | - | 20 | - | $6,783 | $153,105 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 6 | Little Nicholas | $129,769 | -13.8% | 30 | - | $4,325 | $1,147,498 | 5 | Cinéart | false | false |
| 9 | 5 | Jennifer's Body | $121,929 | -31.5% | 35 | - | $3,483 | $397,542 | 2 | 20th Century Fox International | false | false |
| 10 | 7 | Lucky Luke | $85,581 | -30% | 24 | +3 | $3,565 | $243,698 | 2 | Les Films de l'Elysée | false | false |
| 11 | 9 | Inglourious Basterds | $78,656 | -25.3% | 47 | -16 | $1,673 | $4,992,643 | 11 | Universal Pictures International (UPI) | false | false |
| 12 | 8 | The Ugly Truth | $68,626 | -37.2% | 29 | -4 | $2,366 | $1,414,899 | 6 | Sony Pictures Releasing | false | false |
| 13 | - | Astro Boy | $66,979 | - | 44 | - | $1,522 | $85,309 | 1 | Belga Films | true | false |
| 14 | 12 | The White Ribbon | $61,974 | +9.2% | 16 | +2 | $3,873 | $171,193 | 2 | Cinéart | false | false |
| 15 | 11 | G-Force | $39,780 | -30.9% | 37 | -6 | $1,075 | $2,900,502 | 14 | Walt Disney Pictures | false | false |
| 16 | 10 | District 9 | $37,053 | -39.6% | 22 | -9 | $1,684 | $839,881 | 5 | Sony Pictures Releasing | false | false |
| 17 | 15 | Whatever Works | $31,389 | -3.1% | 11 | -5 | $2,853 | $348,403 | 5 | Paradiso Entertainment | false | false |
| 18 | - | My Queen Karo | $27,100 | - | 10 | - | $2,710 | $29,146 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 19 | 13 | Julie & Julia | $24,789 | -43.9% | 12 | -5 | $2,065 | $247,189 | 3 | Sony Pictures Releasing | false | false |
| 20 | - | Sinterklaas en de verdwenen pakjesboot | $22,035 | - | 11 | - | $2,003 | $22,035 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 21 | 14 | The Final Destination | $20,545 | -42.7% | 23 | -12 | $893 | $1,390,277 | 7 | Warner Bros. | false | false |
| 22 | 20 | Divorces! | $18,192 | +22.8% | 7 | - | $2,598 | $38,527 | 2 | Cinéart | false | false |
| 23 | 19 | Lilly the Witch: The Dragon and the Magic Book | $15,350 | -3% | 10 | - | $1,535 | $87,334 | 37 | Kinepolis Film Distribution (KFD) | false | false |
| 24 | - | Cinéman | $14,910 | - | 16 | - | $931 | $15,117 | 1 | N/A | true | false |
| 25 | 18 | Ice Age: Dawn of the Dinosaurs | $13,775 | -36.9% | 16 | -7 | $860 | $9,710,900 | 18 | 20th Century Fox International | false | false |
| 26 | 22 | The Storm | $12,711 | -6.8% | 5 | -2 | $2,542 | $122,282 | 5 | Universal Pictures International (UPI) | false | false |
| 27 | 21 | A Perfect Getaway | $10,578 | -25.1% | 1 | -3 | $10,578 | $680,230 | 10 | A-Film Distribution | false | false |
| 28 | 23 | The Taking of Pelham 123 | $9,762 | -12.1% | 2 | -2 | $4,881 | $1,550,711 | 14 | Sony Pictures Releasing | false | false |
| 29 | 17 | Carriers | $8,409 | -67.2% | 7 | -5 | $1,201 | $113,545 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 30 | 16 | Halloween II | $8,163 | -68.9% | 3 | -5 | $2,721 | $34,808 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 31 | 28 | One for the Road | $5,706 | -8.5% | 3 | - | $1,902 | $25,720 | 3 | Cinéart | false | false |
| 32 | 31 | Harry Potter and the Half-Blood Prince | $3,936 | -18.1% | 10 | -7 | $393 | $9,304,830 | 16 | Warner Bros. | false | false |
| 33 | 29 | Antichrist | $3,298 | -42.8% | 4 | -3 | $824 | $174,438 | 7 | N/A | false | false |
| 34 | 24 | Funny People | $2,872 | -68.7% | 3 | -6 | $957 | $185,215 | 4 | Universal Pictures International (UPI) | false | false |
