| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 12 | Cloudy with a Chance of Meatballs | $259,461 | +1,578.1% | 81 | +80 | $3,203 | $1,694,013 | 3 | Sony Pictures Releasing | false | false |
| 2 | 1 | Surrogates | $87,575 | -28.9% | 60 | -6 | $1,459 | $500,137 | 3 | Walt Disney Pictures | false | false |
| 3 | - | Amar a morir | $76,842 | - | 61 | - | $1,259 | $76,842 | 1 | United International Pictures | true | false |
| 4 | 2 | Drag Me to Hell | $64,449 | -19.5% | 30 | -8 | $2,148 | $195,429 | 2 | United International Pictures | false | false |
| 5 | 3 | The Final Destination | $48,591 | -21.8% | 39 | -6 | $1,245 | $1,123,394 | 6 | Cine Colombia | false | false |
| 6 | 4 | District 9 | $46,327 | -23.5% | 38 | -2 | $1,219 | $422,527 | 4 | Sony Pictures Releasing | false | false |
| 7 | 8 | Julie & Julia | $28,785 | -16.9% | 11 | - | $2,616 | $84,771 | 2 | Sony Pictures Releasing | false | false |
| 8 | 7 | The Dolphin: Story of a Dreamer | $25,051 | -29% | 27 | -4 | $927 | $77,489 | 2 | 20th Century Fox International | false | false |
| 9 | 5 | The Taking of Pelham 123 | $22,473 | -57.3% | 31 | -20 | $724 | $707,063 | 6 | Sony Pictures Releasing | false | false |
| 10 | - | Jennifer's Body | $21,932 | - | 10 | - | $2,193 | $21,932 | 1 | 20th Century Fox International | true | false |
| 11 | 6 | The Ugly Truth | $20,492 | -47.8% | 29 | -10 | $706 | $795,267 | 8 | Sony Pictures Releasing | false | false |
| 12 | - | The Informant! | $19,298 | - | 10 | - | $1,929 | $19,535 | 1 | Warner Bros. | true | false |
| 13 | 9 | Coco Before Chanel | $18,718 | -23.9% | 10 | +2 | $1,871 | $58,194 | 2 | Warner Bros. | false | false |
| 14 | - | An American Crime | $13,830 | - | 15 | - | $922 | $13,830 | 1 | Cine Colombia | true | false |
| 15 | - | My Sassy Girl | $12,542 | - | 7 | - | $1,791 | $12,542 | 1 | Venus | true | false |
| 16 | 10 | Aliens in the Attic | $12,088 | -31% | 40 | +3 | $302 | $352,977 | 6 | 20th Century Fox International | false | false |
| 17 | 17 | The Reader | $9,794 | +97.6% | 11 | +7 | $890 | $123,360 | 6 | Cineplex | false | false |
| 18 | 11 | The Uninvited | $7,905 | -52% | 16 | -5 | $494 | $205,619 | 7 | United International Pictures | false | false |
| 19 | 15 | The Hangover | $6,355 | +4% | 6 | -3 | $1,059 | $949,287 | 10 | Warner Bros. | false | false |
| 20 | 23 | In Bruges | $4,090 | +425.7% | 8 | +7 | $511 | $37,572 | 7 | Cine Colombia | false | false |
| 21 | 16 | The Accidental Husband | $2,353 | -57% | 6 | -5 | $392 | $191,964 | 6 | Walt Disney Pictures | false | false |
| 22 | 14 | Orphan | $2,341 | -65% | 7 | -9 | $334 | $571,572 | 9 | Warner Bros. | false | false |
| 23 | 13 | Shorts | $1,369 | -80.9% | 16 | -11 | $85 | $339,309 | 8 | Warner Bros. | false | false |
| 24 | 20 | Public Enemies | $1,045 | -12.5% | 3 | - | $348 | $506,386 | 9 | United International Pictures | false | false |
| 25 | 18 | G-Force | $1,005 | -76.6% | 9 | -4 | $111 | $2,645,099 | 12 | Walt Disney Pictures | false | false |
| 26 | 19 | Blackout 2009 Re-release | $670 | -78.1% | 5 | -5 | $134 | $19,630 | 3 | Cine Colombia | false | false |
| 27 | 22 | Elegy | $540 | -32.8% | 2 | -1 | $270 | $107,930 | 15 | Cine Colombia | false | false |
