| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Proposal | $47,094 | -43.5% | 30 | - | $1,569 | $743,905 | 4 | Walt Disney Pictures | false | false |
| 2 | 2 | The Hangover | $27,395 | -32.8% | 14 | -1 | $1,956 | $213,033 | 3 | Warner Bros. | false | false |
| 3 | - | G-Force | $23,850 | - | 31 | - | $769 | $23,850 | - | Walt Disney Pictures | - | false |
| 4 | 3 | G.I. Joe: The Rise of Cobra | $15,787 | -52.7% | 13 | -9 | $1,214 | $1,936,980 | 6 | United International Pictures | false | false |
| 5 | 4 | Orphan | $11,485 | -63.7% | 9 | -11 | $1,276 | $478,163 | 5 | Warner Bros. | false | false |
| 6 | 7 | Land of the Lost | $4,954 | +25.1% | 5 | -1 | $990 | $122,272 | 4 | United International Pictures | false | false |
| 7 | 5 | Transformers: Revenge of the Fallen | $4,823 | -21.1% | 2 | -1 | $2,411 | $4,469,608 | 12 | United International Pictures | false | false |
| 8 | 12 | Aliens in the Attic | $4,076 | +702.4% | 3 | +2 | $1,358 | $190,963 | 6 | 20th Century Fox International | false | false |
| 9 | 9 | Public Enemies | $3,541 | +149.9% | 4 | +3 | $885 | $635,146 | 8 | United International Pictures | false | false |
| 10 | 8 | Ice Age: Dawn of the Dinosaurs | $3,518 | +66.2% | 4 | +2 | $879 | $2,113,727 | 11 | 20th Century Fox International | false | false |
| 11 | 11 | Harry Potter and the Half-Blood Prince | $2,993 | +187.5% | 2 | - | $1,496 | $3,526,313 | 9 | Warner Bros. | false | false |
| 12 | 6 | Up | $812 | -85.8% | 1 | -4 | $812 | $1,478,086 | 7 | Walt Disney Pictures | false | false |
| 13 | 10 | The Taking of Pelham 123 | $97 | -91.8% | 1 | -4 | $97 | $390,035 | 5 | Sony Pictures Releasing | false | false |
