| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Inglourious Basterds | $5,935,952 | - | 444 | - | $13,369 | $5,935,952 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | The Time Traveler's Wife | $1,511,465 | -35.2% | 431 | +6 | $3,506 | $6,254,287 | 2 | Entertainment Film Distributors | false | false |
| 3 | 3 | G-Force | $1,080,940 | -30.6% | 459 | -9 | $2,354 | $17,434,007 | 4 | Walt Disney Pictures | false | false |
| 4 | 2 | Aliens in the Attic | $1,060,495 | -51.5% | 457 | +22 | $2,320 | $4,777,125 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | Harry Potter and the Half-Blood Prince | $987,563 | -36% | 404 | -60 | $2,444 | $79,556,431 | 6 | Warner Bros. | false | false |
| 6 | - | Dance Flick | $763,901 | - | 322 | - | $2,372 | $763,901 | - | Paramount Pictures International | - | false |
| 7 | 5 | G.I. Joe: The Rise of Cobra | $751,871 | -45% | 401 | -41 | $1,874 | $8,335,674 | 3 | Paramount Pictures International | false | false |
| 8 | 6 | The Ugly Truth | $744,422 | -44.4% | 374 | -24 | $1,990 | $8,679,553 | 3 | Sony Pictures Releasing | false | false |
| 9 | 8 | Ice Age: Dawn of the Dinosaurs | $555,070 | -34% | 398 | -19 | $1,394 | $54,971,723 | 8 | 20th Century Fox International | false | false |
| 10 | 9 | The Proposal | $446,781 | -39.4% | 302 | -78 | $1,479 | $18,275,348 | 3 | Walt Disney Pictures | false | false |
| 11 | 11 | Orphan | $381,785 | -39.1% | 252 | -26 | $1,515 | $3,538,218 | 3 | Optimum Releasing | false | false |
| 12 | 7 | Bandslam | $285,366 | -72.6% | 382 | +5 | $747 | $2,004,653 | 2 | Entertainment One | false | false |
| 13 | - | Shorts | $283,685 | - | 342 | - | $829 | $283,685 | 1 | Warner Bros. | true | false |
| 14 | 12 | The Taking of Pelham 123 | $259,864 | -51.5% | 230 | -108 | $1,129 | $7,791,823 | 4 | Sony Pictures Releasing | false | false |
| 15 | - | A Perfect Getaway | $233,418 | - | 216 | - | $1,080 | $1,400,593 | - | Momentum Pictures | - | false |
| 16 | 13 | Coco Before Chanel | $218,288 | -26% | 123 | +12 | $1,774 | $3,080,060 | 4 | Optimum Releasing | false | false |
| 17 | - | I Love You, Beth Cooper | $203,870 | - | 199 | - | $1,024 | $203,870 | 1 | 20th Century Fox International | true | false |
| 18 | 14 | The Hangover | $153,979 | -36.2% | 110 | -58 | $1,399 | $36,033,624 | 4 | Warner Bros. | false | false |
| 19 | - | Kanthaswamy | $118,514 | - | 11 | - | $10,774 | $118,514 | 1 | Ayngaran International | true | false |
| 20 | 17 | Mesrine: Killer Instinct | $93,896 | -36.9% | 56 | -5 | $1,676 | $785,545 | 4 | Momentum Pictures | false | false |
| 21 | 19 | Sin Nombre | $75,204 | -30.1% | 27 | +4 | $2,785 | $260,033 | 2 | Revolver Entertainment | false | false |
| 22 | 22 | Moon | $64,644 | -20.2% | 52 | +5 | $1,243 | $1,813,302 | 6 | Warner Bros. | false | false |
| 23 | 16 | Imagine That | $62,456 | -65.6% | 179 | -47 | $348 | $484,436 | 4 | Paramount Pictures International | false | false |
| 24 | 15 | Kaminey | $62,378 | -66.3% | 28 | - | $2,227 | $351,491 | 2 | UTV Motion Pictures | false | false |
| 25 | 18 | Life Partner | $56,492 | -61.8% | 28 | -4 | $2,017 | $339,839 | 2 | Studio 18 | false | false |
| 26 | 25 | Mid-August Lunch | $47,068 | +27.4% | 13 | +6 | $3,620 | $116,721 | 2 | Artificial Eye | false | false |
| 27 | 31 | Hannah Montana: The Movie | $42,727 | +145.5% | 166 | +83 | $257 | $13,937,675 | 17 | Walt Disney Pictures | false | false |
| 28 | 20 | Love Aaj Kal | $40,167 | -55.2% | 34 | +1 | $1,181 | $1,671,956 | 4 | Eros Worldwide | false | false |
| 29 | 21 | Brüno | $26,245 | -69.8% | 43 | -80 | $610 | $25,793,264 | 7 | Universal Pictures International (UPI) | false | false |
| 30 | 29 | Monsters vs. Aliens | $19,267 | -1.7% | 78 | -3 | $247 | $34,956,968 | 21 | Paramount Pictures International | false | false |
| 31 | 23 | Land of the Lost | $16,758 | -66.7% | 52 | -115 | $322 | $2,800,650 | 4 | Universal Pictures International (UPI) | false | false |
| 32 | 39 | Coraline | $14,843 | +343.5% | 79 | +61 | $187 | $12,193,282 | 16 | Universal Pictures International (UPI) | false | false |
| 33 | 27 | My Sister's Keeper | $14,561 | -36.4% | 20 | -7 | $728 | $10,406,236 | 9 | Entertainment Film Distributors | false | false |
| 34 | 26 | Transformers: Revenge of the Fallen | $14,239 | -46.6% | 21 | -17 | $678 | $44,383,558 | 10 | Paramount Pictures International | false | false |
| 35 | 28 | Antichrist | $13,831 | -30.8% | 19 | -6 | $727 | $582,998 | 5 | Artificial Eye | false | false |
| 36 | 30 | Public Enemies | $7,152 | -61% | 11 | -12 | $650 | $11,334,699 | 8 | Universal Pictures International (UPI) | false | false |
| 37 | - | Afterschool | $6,404 | - | 5 | - | $1,280 | $6,404 | 1 | - | true | false |
| 38 | 32 | Adam | $5,646 | -52.2% | 4 | -13 | $1,411 | $110,697 | 3 | 20th Century Fox International | false | false |
| 39 | 24 | Night at the Museum: Battle of the Smithsonian | $5,430 | -88.7% | 28 | -90 | $193 | $32,825,190 | 14 | 20th Century Fox International | false | false |
| 40 | 36 | Looking for Eric | $4,636 | +2% | 4 | -2 | $1,159 | $2,142,095 | 11 | Entertainment Film Distributors | false | false |
| 41 | 35 | 35 Shots of Rum | $4,483 | -17.7% | 5 | +1 | $896 | $313,201 | 7 | New Wave Films | false | false |
| 42 | 34 | Home | $4,291 | -26.6% | 8 | +1 | $536 | $41,240 | 3 | Soda Pictures | false | false |
| 43 | 40 | The Private Lives of Pippa Lee | $3,643 | +14.1% | 9 | +5 | $404 | $311,672 | 7 | Icon Film Distribution | false | false |
| 44 | 41 | Skin | $3,123 | +7.8% | 4 | +2 | $780 | $44,232 | 5 | ICA Films | false | false |
| 45 | 33 | Frozen River | $2,973 | -56.8% | 7 | -1 | $424 | $157,842 | 6 | Axiom Films | false | false |
| 46 | 37 | Sunshine Cleaning | $2,205 | -51.3% | 1 | -2 | $2,205 | $675,115 | 9 | N/A | false | false |
| 47 | 43 | The Yes Men Fix the World | $2,033 | -9.4% | 2 | - | $1,016 | $24,700 | 3 | Periscoop Film | false | false |
| 48 | 52 | In the Loop | $1,910 | +263.1% | 1 | - | $1,910 | $3,545,746 | 19 | Optimum Releasing | false | false |
| 49 | 42 | Drag Me to Hell | $937 | -66.5% | 1 | - | $937 | $10,503,062 | 13 | Lionsgate Films | false | false |
| 50 | 56 | Kisses | $881 | +197.6% | 3 | +1 | $293 | $28,128 | 40 | Element Films | false | false |
| 51 | 44 | Crossing Over | $690 | -65.1% | 1 | - | $690 | $20,689 | 4 | Entertainment Film Distributors | false | false |
| 52 | - | Chiko | $548 | - | 1 | - | $548 | $548 | 1 | Vertigo Films | true | false |
| 53 | 49 | Beautiful Losers | $535 | -52.6% | 1 | - | $535 | $7,678 | 3 | Revolver Entertainment | false | false |
| 54 | 45 | Last Chance Harvey | $510 | -72.6% | 2 | - | $255 | $3,391,327 | 12 | Momentum Pictures | false | false |
| 55 | 51 | Rudo y Cursi | $474 | -41.4% | 1 | - | $474 | $270,264 | 9 | Optimum Releasing | false | false |
| 56 | 64 | Anything for Her | $361 | +993.9% | 1 | - | $361 | $454,261 | 12 | - | false | false |
| 57 | 48 | Telstar: The Joe Meek Story | $139 | -88.2% | 1 | - | $139 | $108,880 | 10 | N/A | false | false |
| 58 | 55 | Rumba | $86 | -73.7% | 1 | - | $86 | $6,437 | 4 | - | false | false |
| 59 | 68 | Shifty | $33 | +6.5% | 1 | - | $33 | $244,579 | 18 | - | false | false |
| 60 | 50 | Synecdoche, New York | $33 | -96.1% | 1 | -1 | $33 | $875,104 | 15 | Revolver Entertainment | false | false |
| 61 | 46 | Katyn | $33 | -97.9% | 1 | -2 | $33 | $234,852 | 10 | Artificial Eye | false | false |
| 62 | 63 | Is Anybody There? | $33 | - | 1 | - | $33 | $768,921 | 17 | Optimum Releasing | false | false |
| 63 | 65 | Il Divo | $33 | - | 1 | - | $33 | $586,571 | 23 | Artificial Eye | false | false |
| 64 | 67 | The Young Victoria | $33 | - | 1 | - | $33 | $8,179,212 | 25 | Momentum Pictures | false | false |
