| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Secret in Their Eyes | $793,138 | +5.8% | 71 | +5 | $11,170 | $1,950,427 | 2 | Distribution Company | false | false |
| 2 | 2 | Dad for a Day | $187,315 | -33.6% | 75 | - | $2,497 | $1,038,781 | 3 | Walt Disney Pictures | false | false |
| 3 | 5 | Ice Age: Dawn of the Dinosaurs | $175,972 | -22.8% | 101 | -7 | $1,742 | $7,718,091 | 8 | 20th Century Fox International | false | false |
| 4 | 6 | The Hangover | $151,673 | -20.1% | 41 | - | $3,699 | $425,934 | 2 | Warner Bros. | false | false |
| 5 | 3 | G-Force | $136,384 | -50.9% | 113 | - | $1,206 | $1,692,346 | 4 | Walt Disney Pictures | false | false |
| 6 | 4 | Harry Potter and the Half-Blood Prince | $95,199 | -58.4% | 114 | -29 | $835 | $4,345,741 | 5 | Warner Bros. | false | false |
| 7 | 8 | Drag Me to Hell | $85,271 | -37.3% | 36 | - | $2,368 | $281,654 | 2 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Hannah Montana: The Movie | $77,228 | -51.8% | 68 | +1 | $1,135 | $304,196 | 2 | Walt Disney Pictures | false | false |
| 9 | 9 | Public Enemies | $74,271 | -39% | 56 | +5 | $1,326 | $908,034 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | - | The Haunting in Connecticut | $61,590 | - | 24 | - | $2,566 | $61,590 | 1 | Alfa Films | true | false |
| 11 | - | The Wave | $57,219 | - | 18 | - | $3,178 | $57,219 | 1 | Impacto Cine | true | false |
| 12 | - | Aliens in the Attic | $43,175 | - | 32 | - | $1,349 | $43,175 | 1 | 20th Century Fox International | true | false |
| 13 | 10 | G.I. Joe: The Rise of Cobra | $38,663 | -53% | 54 | -13 | $715 | $406,721 | 3 | Paramount Pictures International | false | false |
| 14 | 12 | My Sister's Keeper | $24,490 | <0.1% | 25 | +1 | $979 | $140,627 | 3 | Distribution Company | false | false |
| 15 | 11 | The Taking of Pelham 123 | $22,617 | -39.2% | 40 | -3 | $565 | $941,237 | 6 | Sony Pictures Releasing | false | false |
| 16 | - | The Girl in the Park | $12,206 | - | 13 | - | $938 | $12,206 | 1 | CDI Films | true | false |
| 17 | 16 | Transformers: Revenge of the Fallen | $7,478 | +10.2% | 9 | - | $830 | $2,501,357 | 9 | Paramount Pictures International | false | false |
| 18 | 15 | The Secret of the Grain | $7,267 | -43.6% | 7 | - | $1,038 | $68,267 | 4 | N/A | false | false |
| 19 | - | Mentiras piadosas | $7,202 | - | 6 | - | $1,200 | $7,202 | 1 | N/A | true | false |
| 20 | 14 | The Proposal | $6,589 | -50% | 16 | -6 | $411 | $881,339 | 8 | Walt Disney Pictures | false | false |
| 21 | 13 | Defiance | $6,260 | -65.8% | 15 | -8 | $417 | $108,084 | 3 | N/A | false | false |
| 22 | 20 | Solstice | $5,929 | +95.5% | 10 | +3 | $592 | $275,219 | 7 | Distribution Company | false | false |
| 23 | 19 | Days and Clouds | $4,688 | +13.8% | 9 | +5 | $520 | $91,405 | 5 | Impacto Cine | false | false |
| 24 | 21 | State of Play | $4,431 | +46.5% | 15 | +9 | $295 | $528,918 | 11 | Universal Pictures International (UPI) | false | false |
| 25 | 17 | I've Loved You So Long | $3,141 | -53.4% | 5 | -1 | $628 | $194,736 | 6 | Alfa Films | false | false |
| 26 | 18 | Too Much Romance... It's Time for Stuffed Peppers | $3,094 | -46.7% | 4 | -1 | $773 | $26,321 | 3 | Primer Plano Film Group | false | false |
| 27 | 27 | Last Chance Harvey | $2,455 | +135.6% | 6 | +4 | $409 | $471,162 | 12 | Distribution Company | false | false |
| 28 | 31 | A Christmas Tale | $2,279 | +554.9% | 7 | +5 | $325 | $84,906 | 8 | Pachamama Cine | false | false |
| 29 | 22 | Felicitas | $1,075 | -58.9% | 3 | -2 | $358 | $446,521 | 11 | Pachamama Cine | false | false |
| 30 | 24 | 100% lucha, el amo de los clones | $667 | -60.2% | 7 | -7 | $95 | $282,787 | 6 | Primer Plano Film Group | false | false |
| 31 | 29 | The Unborn | $613 | -3.5% | 3 | +2 | $204 | $776,427 | 14 | Universal Pictures International (UPI) | false | false |
| 32 | 23 | Up | $548 | -71.3% | 6 | -2 | $91 | $3,428,156 | 11 | Walt Disney Pictures | false | false |
| 33 | 34 | Breath 2009 Re-release | $458 | +114% | 4 | +3 | $114 | $19,558 | 4 | Distribution Company | false | false |
| 34 | 32 | The Secrets | $376 | +22.5% | 2 | - | $188 | $12,514 | 6 | Distribution Company | false | false |
| 35 | 35 | Che: Part Two | $292 | +74.9% | 3 | +2 | $97 | $53,077 | 10 | Alfa Films | false | false |
| 36 | 39 | Some Place Nowhere | $241 | +125.2% | 1 | -1 | $241 | $1,102 | 3 | N/A | false | false |
| 37 | 30 | All the Lonely People | $217 | -47.1% | 3 | - | $72 | $18,319 | 10 | Primer Plano Film Group | false | false |
| 38 | 26 | Home | $213 | -82.4% | 1 | -1 | $213 | $23,969 | 5 | Primer Plano Film Group | false | false |
| 39 | 38 | Inspector Bellamy | $141 | +17.5% | 1 | - | $141 | $139,977 | 12 | Alfa Films | false | false |
| 40 | 28 | Katyn | $94 | -90.9% | 1 | -2 | $94 | $20,576 | 6 | N/A | false | false |
| 41 | 36 | The Reader | $78 | -42.6% | 16 | +14 | $4 | $572,273 | 16 | Pachamama Cine | false | false |
| 42 | 37 | Pride and Glory | $76 | -41.1% | 1 | -1 | $76 | $132,056 | 9 | Distribution Company | false | false |
| 43 | 41 | Night at the Museum: Battle of the Smithsonian | $65 | +712.5% | 2 | - | $32 | $2,537,926 | 14 | 20th Century Fox International | false | false |
| 44 | 40 | Lorna's Silence | $31 | +93.8% | 1 | - | $31 | $91,085 | 15 | Distribution Company | false | false |
