| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G.I. Joe: The Rise of Cobra | $480,651 | - | 18 | - | $26,702 | $710,097 | 1 | United International Pictures | true | false |
| 2 | 1 | Up | $326,383 | -30.9% | 18 | - | $18,132 | $1,365,903 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Harry Potter and the Half-Blood Prince | $70,498 | -55.9% | 17 | - | $4,146 | $2,861,631 | 4 | Warner Bros. | false | false |
| 4 | 3 | Public Enemies | $24,536 | -69.6% | 14 | -3 | $1,752 | $549,585 | 3 | United International Pictures | false | false |
| 5 | 4 | Transformers: Revenge of the Fallen | $18,703 | -63.8% | 7 | -10 | $2,671 | $7,163,683 | 7 | United International Pictures | false | false |
| 6 | 5 | Ice Age: Dawn of the Dinosaurs | $9,659 | -70.9% | 6 | -7 | $1,609 | $2,047,069 | 6 | 20th Century Fox International | false | false |
| 7 | - | Brüno | $8,628 | - | 6 | - | $1,438 | $10,908 | 1 | Long Shong Entertainment Multimedia Company | true | false |
| 8 | 6 | Management | $6,814 | -60.5% | 6 | -2 | $1,135 | $45,635 | 2 | N/A | false | false |
| 9 | 8 | Jodhaa Akbar 2009 Re-release | $3,937 | -35.1% | 2 | - | $1,968 | $36,440 | 3 | N/A | false | false |
| 10 | 7 | Detective Conan: The Raven Chaser | $2,715 | -72.4% | 3 | -5 | $905 | $318,387 | 5 | N/A | false | false |
| 11 | 10 | Synecdoche, New York | $2,330 | -45.5% | 2 | - | $1,165 | $12,561 | 2 | N/A | false | false |
| 12 | 11 | Gomorrah | $2,263 | -15.9% | 1 | - | $2,263 | $8,624 | 2 | N/A | false | false |
| 13 | 12 | Boy A | $471 | -38.8% | 1 | - | $471 | $29,229 | 5 | N/A | false | false |
| 14 | 14 | The Hangover | $69 | -73.6% | 1 | - | $69 | $512,666 | 9 | Warner Bros. | false | false |
| 15 | 15 | Cobalt Blue | $38 | -63.5% | 1 | - | $38 | $301 | 2 | 20th Century Fox International | false | false |
