| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Proposal | $37,308 | - | 8 | - | $4,663 | $52,510 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $36,997 | -40.8% | 21 | - | $1,761 | $1,065,318 | 5 | 20th Century Fox International | false | false |
| 3 | 2 | Harry Potter and the Half-Blood Prince | $20,629 | -33.9% | 10 | - | $2,062 | $248,274 | 3 | Warner Bros. | false | false |
| 4 | 3 | Brüno | $15,577 | -38.2% | 10 | - | $1,557 | $311,305 | 4 | N/A | false | false |
| 5 | 4 | The Hangover | $6,042 | -33.3% | 6 | - | $1,007 | $312,751 | 8 | Warner Bros. | false | false |
| 6 | 5 | The Last House on the Left | $5,233 | -34.8% | 7 | - | $747 | $22,174 | 2 | United International Pictures | false | false |
| 7 | 8 | Angels & Demons | $2,080 | +13.3% | 2 | - | $1,040 | $455,824 | 12 | Sony Pictures Releasing | false | false |
| 8 | 6 | Two Lovers | $1,933 | -40.2% | 2 | - | $966 | $9,090 | 2 | N/A | false | false |
| 9 | 7 | Drag Me to Hell | $1,748 | -32.5% | 4 | - | $437 | $64,856 | 6 | Walt Disney Pictures | false | false |
| 10 | 9 | Transformers: Revenge of the Fallen | $999 | -43% | 5 | - | $199 | $100,887 | 6 | United International Pictures | false | false |
