| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Half-Blood Prince | $919,220 | -30.3% | 143 | - | $6,428 | $6,695,946 | 3 | Warner Bros. | false | false |
| 2 | 2 | Ice Age: Dawn of the Dinosaurs | $604,190 | -18% | 160 | - | $3,776 | $7,065,108 | 5 | 20th Century Fox International | false | false |
| 3 | - | G-Force | $603,679 | - | 79 | - | $7,641 | $605,800 | 1 | Walt Disney Pictures | true | false |
| 4 | - | The Taking of Pelham 123 | $415,983 | - | 45 | - | $9,244 | $422,189 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | Public Enemies | $399,239 | -22% | 50 | - | $7,984 | $1,221,673 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Brüno | $159,829 | -33.3% | 40 | -2 | $3,995 | $1,957,170 | 4 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | Het geheim van Mega Mindy | $128,362 | -18.3% | 33 | - | $3,889 | $1,161,857 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | 5 | Luke and Lucy: The Texas Rangers | $125,557 | -25.2% | 52 | - | $2,414 | $352,802 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 9 | 7 | The Proposal | $108,623 | -21.8% | 41 | +4 | $2,649 | $2,251,813 | 7 | Walt Disney Pictures | false | false |
| 10 | - | I Love You, Man | $92,045 | - | 20 | - | $4,602 | $163,448 | 1 | Universal Pictures International (UPI) | true | false |
| 11 | 8 | Transformers: Revenge of the Fallen | $77,751 | -30.2% | 52 | -20 | $1,495 | $2,843,315 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | 9 | The Hangover | $77,693 | -17.9% | 24 | -9 | $3,237 | $1,625,111 | 7 | Warner Bros. | false | false |
| 13 | 10 | Hannah Montana: The Movie | $42,899 | -31.2% | 34 | -8 | $1,261 | $519,416 | 4 | Walt Disney Pictures | false | false |
| 14 | 12 | Ghosts of Girlfriends Past | $27,662 | -25.8% | 11 | -5 | $2,514 | $524,871 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 15 | 13 | Angels & Demons | $26,672 | -26.1% | 9 | -5 | $2,963 | $4,597,401 | 12 | Sony Pictures Releasing | false | false |
| 16 | 11 | Fighting | $22,664 | -54.9% | 12 | -3 | $1,888 | $206,364 | 3 | Universal Pictures International (UPI) | false | false |
| 17 | 15 | Drag Me to Hell | $19,859 | -34.7% | 14 | -7 | $1,418 | $558,157 | 6 | Belga Films | false | false |
| 18 | 14 | Blame It on Mum | $17,843 | -45.3% | 11 | -2 | $1,622 | $76,896 | 2 | Cinéart | false | false |
| 19 | - | Towelhead | $14,839 | - | 11 | - | $1,349 | $16,338 | 1 | Benelux Film Distributors | true | false |
| 20 | 17 | Broken Embraces | $11,706 | -12.4% | 15 | +2 | $780 | $646,609 | 11 | Alternative Films | false | false |
| 21 | 16 | State of Play | $8,310 | -57.7% | 6 | -8 | $1,385 | $539,990 | 7 | Universal Pictures International (UPI) | false | false |
| 22 | 23 | Looking for Eric | $7,656 | +36.3% | 15 | - | $510 | $272,958 | 8 | Cinéart | false | false |
| 23 | - | Kabuli Kid | $7,056 | - | 4 | - | $1,764 | $7,902 | 1 | N/A | true | false |
| 24 | - | Passengers | $6,908 | - | 6 | - | $1,151 | $8,003 | 1 | Paradiso Entertainment | true | false |
| 25 | 21 | Disgrace | $5,942 | -18.9% | 5 | - | $1,188 | $17,743 | 2 | A-Film Distribution | false | false |
| 26 | 25 | A Town Called Panic | $4,208 | +5.9% | 11 | - | $382 | $136,561 | 7 | Cinéart | false | false |
| 27 | 18 | Night at the Museum: Battle of the Smithsonian | $4,161 | -64.9% | 9 | -11 | $462 | $2,442,939 | 11 | 20th Century Fox International | false | false |
| 28 | 20 | The French Kissers | $3,759 | -62.3% | 8 | -9 | $469 | $280,856 | 6 | Alternative Films | false | false |
| 29 | - | Alternate Weeks (and Half the Vacation) | $3,383 | - | 8 | - | $422 | $9,188 | 1 | Les Films de l'Elysée | true | false |
| 30 | 30 | Mammoth | $2,119 | +0.9% | 6 | - | $353 | $22,468 | 4 | A-Film Distribution | false | false |
| 31 | 28 | Coraline | $1,936 | -23.6% | 8 | +1 | $242 | $455,204 | 8 | Universal Pictures International (UPI) | false | false |
| 32 | 31 | The Girl with the Dragon Tattoo | $1,780 | -15.2% | 4 | -1 | $445 | $573,959 | 11 | Benelux Film Distributors | false | false |
| 33 | 29 | Sans rancune! | $1,717 | -18.5% | 3 | -1 | $572 | $34,973 | 5 | N/A | false | false |
| 34 | 22 | High Lane | $1,519 | -77% | 2 | -5 | $759 | $72,583 | 4 | Benelux Film Distributors | false | false |
| 35 | 24 | 17 Again | $1,423 | -65.1% | 2 | -2 | $711 | $1,298,598 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 36 | - | The Market: A Tale of Trade | $1,281 | - | 4 | - | $320 | $1,412 | 1 | N/A | true | false |
| 37 | - | Two-Legged Horse | $1,273 | - | 2 | - | $636 | $4,393 | 1 | N/A | true | false |
| 38 | 39 | Puisque nous sommes nés | $918 | +56.9% | 3 | - | $306 | $5,885 | 3 | Cinéart | false | false |
| 39 | 19 | Personal Effects | $871 | -92.3% | 1 | -4 | $871 | $17,905 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 40 | 36 | The Country Teacher 2009 Re-release | $589 | -51.4% | 2 | - | $294 | $8,511 | 3 | Cinéart | false | false |
| 41 | 35 | The Reader | $588 | -58.9% | 2 | -1 | $294 | $911,687 | 22 | Benelux Film Distributors | false | false |
| 42 | 26 | Management | $22 | -99.3% | 1 | -3 | $22 | $30,312 | 4 | Kinepolis Film Distribution (KFD) | false | false |
