| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $789,176 | - | 87 | - | $9,070 | $789,176 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $323,355 | -25.9% | 93 | - | $3,476 | $2,507,137 | 3 | NuMetro Distribution | false | false |
| 3 | 2 | The Proposal | $273,629 | -28.6% | 65 | - | $4,209 | $944,671 | 2 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | Transformers: Revenge of the Fallen | $124,259 | -33.5% | 87 | -9 | $1,428 | $1,994,782 | 4 | United International Pictures | false | false |
| 5 | 4 | The Hangover | $102,182 | -13.6% | 53 | -3 | $1,927 | $1,217,236 | 5 | NuMetro Distribution | false | false |
| 6 | 5 | Knowing | $76,802 | -32.1% | 72 | -1 | $1,066 | $586,941 | 3 | United International Pictures | false | false |
| 7 | 6 | Brüno | $66,712 | -29.3% | 43 | - | $1,551 | $231,952 | 2 | United International Pictures | false | false |
| 8 | - | The Haunting in Connecticut | $33,126 | - | 25 | - | $1,325 | $33,126 | 1 | NuMetro Distribution | true | false |
| 9 | 7 | Night at the Museum: Battle of the Smithsonian | $25,461 | -37.5% | 36 | -24 | $707 | $1,633,849 | 9 | NuMetro Distribution | false | false |
| 10 | 8 | Obsessed | $16,124 | -30.2% | 18 | -3 | $895 | $251,096 | 5 | Ster-Kinekor Pictures | false | false |
| 11 | - | Crossing Over | $15,434 | - | 10 | - | $1,543 | $15,434 | 1 | Ster-Kinekor Pictures | true | false |
| 12 | 9 | Ghosts of Girlfriends Past | $12,547 | -38% | 21 | -14 | $597 | $1,008,293 | 10 | NuMetro Distribution | false | false |
| 13 | 10 | Kambakkht Ishq | $9,858 | -50.1% | 6 | - | $1,643 | $83,980 | 3 | NuMetro Distribution | false | false |
| 14 | 11 | Duplicity | $8,494 | -41.4% | 15 | -8 | $566 | $630,375 | 8 | United International Pictures | false | false |
| 15 | 15 | The Brothers Bloom | $5,463 | -40.1% | 9 | -1 | $607 | $40,419 | 3 | Ster-Kinekor Pictures | false | false |
| 16 | 14 | State of Play | $5,317 | -49.1% | 13 | -3 | $409 | $316,390 | 6 | United International Pictures | false | false |
| 17 | 16 | Welcome to the Sticks | $4,951 | -14.3% | 4 | - | $1,237 | $36,350 | 4 | Ster-Kinekor Pictures | false | false |
| 18 | 17 | The Song of Sparrows | $4,861 | -8.7% | 3 | - | $1,620 | $14,369 | 2 | Ster-Kinekor Pictures | false | false |
| 19 | 20 | Shortkut - The Con Is On | $3,136 | -19.2% | 5 | - | $627 | $9,897 | 2 | Ster-Kinekor Pictures | false | false |
| 20 | 21 | The Burning Plain | $2,903 | -17.2% | 8 | +2 | $362 | $82,342 | 7 | United International Pictures | false | false |
| 21 | 19 | Sunshine Cleaning | $2,798 | -30.9% | 5 | -3 | $559 | $81,764 | 6 | United International Pictures | false | false |
| 22 | 18 | Terminator Salvation | $2,006 | -60.9% | 9 | -9 | $222 | $851,398 | 7 | Ster-Kinekor Pictures | false | false |
| 23 | - | The Uninvited | $321 | - | 2 | - | $160 | $47,887 | 8 | United International Pictures | false | false |
